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Search Results for " tβr-i "
Targets Recommended: TGF-beta/Smad

1

抑制剂 & 化合物

8

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T62483 CJJ300

TGF-beta/Smad Stem Cells
CJJ300 是一种转化生长因子-β(TGF-β)抑制剂(IC50 : 5.3 μM)。CJJ300 通过破坏 TGF-β-TβR-I-TβR-II 信号传导复合物的形成来抑制 TGF-β 信号传导。CJJ300 可抑制细胞迁移。

化合物

CJJ300
Cat.No: T62483
Synonym:
Target: TGF-beta/Smad
Cat. No. Product Name Species Expression System
TMPK-00305 TGFBR1 Protein, Human, Recombinant (mFc & Avi)

tbetaR-I,TGFβRI,TGFbetaRI,LDS2A,A...

Human HEK293 Cells
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1.
TMPK-00306 TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated

TGFbetaRI,TGFBR1,ALK-5,SKR4,LDS2A,TGFB1R1,LDS1A,AAT...

Human HEK293 Cells
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is...
TMPJ-01178 TGFBR1 Protein, Mouse, Recombinant (hFc)

ALK-5,ALK-5ALK5,TGFβRI,tβR-I,LDS1...

Mouse HEK293 Cells
TGF-beta RI, also called ALK-5, is an approximately 55 kDa type I transmembrane serine/threonine receptor kinase. In the presence of TGF-beta, TGF-beta RI forms a complex with, and is phosphorylated by, TGF-beta RII. Phosphorylated TGF-beta RI can then transiently bind and phosphorylate Smad2 and Smad3. TGF-beta functions as a tumor suppressor by inhibiting the cell cycle in the G1 phase. Administration of TGF-beta is able to protect against mammary tumor development in transgenic mouse models i...
TMPY-05771 ALK-5 Protein, Human, Recombinant (hFc)

AAT5,SKR4,TGFR-1,LDS1,transforming growth factor, b...

Human HEK293 Cells
ALK-5 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36.87 kDa and the accession number is P36897-1.
TMPY-01358 ALK-5 Protein, Human, Recombinant (His & hFc)

tβR-I,ALK5,AAT5,TGFR-1,LDS2A,LDS1,transfor...

Human HEK293 Cells
ALK-5 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 38.1 kDa and the accession number is P36897-1.
TMPY-04366 ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST)

LDS1,ALK-5,LDS2A,AAT5,SKR4,transforming growth fact...

Human Baculovirus Insect Cells
ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 62.6 kDa and the accession number is P36897-1.
TMPJ-00261 TGF beta 2 Protein, Mouse/Rat, Recombinant

transforming growth factor β-2,BSC-1 cell growth

Mouse,Rat HEK293 Cells
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the n...
TMPJ-00771 TGF beta 1 Protein, Mouse/Rat, Recombinant

TGFB,TGFbeta,CEDLAP,TGF-beta-1,TGF-beta 1 protein,l...

Mouse,Rat HEK293 Cells
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II)...

重组蛋白

TGFBR1 Protein, Human, Recombinant (mFc & Avi)
Cat.No: TMPK-00305
Species: Human
Expression System: HEK293 Cells
TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated
Cat.No: TMPK-00306
Species: Human
Expression System: HEK293 Cells
TGFBR1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-01178
Species: Mouse
Expression System: HEK293 Cells
ALK-5 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05771
Species: Human
Expression System: HEK293 Cells
ALK-5 Protein, Human, Recombinant (His & hFc)
Cat.No: TMPY-01358
Species: Human
Expression System: HEK293 Cells
ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST)
Cat.No: TMPY-04366
Species: Human
Expression System: Baculovirus Insect Cells
TGF beta 2 Protein, Mouse/Rat, Recombinant
Cat.No: TMPJ-00261
Species: Mouse,Rat
Expression System: HEK293 Cells
TGF beta 1 Protein, Mouse/Rat, Recombinant
Cat.No: TMPJ-00771
Species: Mouse,Rat
Expression System: HEK293 Cells
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