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Search Results for " thymic "

16

抑制剂 & 化合物

4

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T34867	Thymoctonan Thymic humoral factor gamma 2
	Thymoctonan, as a synthetic octapeptide thymic hormone, can repair immunodeficiency of mice cured of plasmacytoma by melphalan.
T16832	S18-000003	ROR	Metabolism
	S18-000003 是口服有活性的维甲酸相关孤儿受体 (RORγt) 选择性抑制剂，在竞争性结合试验中，对 hRORγt 的 IC50值小于 30 nM。它对 RORγt 的选择性比其他 ROR 家族成员 (IC50>10 μM)更高。它可用于银屑病的研究，胸腺畸变风险较低。
T21459	Splenopentin diacetate Thymopoietin III pentapeptide (32-36),SP5,Splenopentin Acetate,醋酸脾脏五肽,Splenin pentapeptide (32-36),Arg-lys-glu-val-tyr	Others	Others
	Splenopentin diacetate (Splenin pentapeptide (32-36)) 是一种合成的免疫调节肽，可以再现脾和胸腺激素胸腺生成素的生物活性。
TP1735L	Influenza HA 126-138 acetate Influenza HA 126-138 acetate(207349-63-1 free base)	Others	Others
	Influenza HA 126-138 acetate 是一种流感病毒血凝素 (HA) 肽乙酸盐，包含氨基酸 126-138。它诱导胸腺和外周 T 细胞凋亡。
TP2324	Thymulin	Immunology/Inflammation related	Immunology/Inflammation
	Thymulin 是一种肽类激素，主要由胸腺上皮细胞产生，具有免疫调节和抗炎作用。
T34866	Thymocartin Thymocartinum,TP 4,Thymopoietin II (32-35),RGH 0206
	Thymocartin (RGH 0206) 是天然存在胸腺因子 (胸腺生成素) 的 32-35 片段。Thymocartin 可用于研究免疫缺陷病。
TP2319	Thymosin β4 acetate(75591-33-4 free base)	Autophagy	Autophagy
	Thymosin β4 acetate(75591-33-4 free base) 是一种胸腺激素，具有多种不同的细胞内和细胞外活性，影响伤口愈合、炎症、纤维化和组织再生。
T11449L	Golotimod Gamma-D-glutamyl-L-tryptophan,SCV 07	Antibiotic	Microbiology/Virology
	Golotimod (SCV 07) 是一种具有抗菌活性的二肽，具有免疫调节活性，能显著提高抗结核治疗的疗效，诱导胸腺和脾脏细胞增殖，调节巨噬细胞功能，抑制 STAT3 信号传导。Golotimod 可用于研究复发性生殖器单纯疱疹病毒 2 （HSV-2）感染和口腔黏膜炎。
TP1030	Thymus factor X TFX-Jelfa,胸腺因子X
	Thymic factor X (TFX-Jelfa) is an aqueous extract from the thymus of a juvenile calf and is a natural stimulator of lymphocyte function.
TP1735	Influenza HA (126-138) Influenza HA 126-138
	Influenza HA (126-138) is a peptide derived from the hemagglutinin (HA) protein of the influenza virus. It consists of amino acids 126-138 and has the ability to induce apoptosis in both thymic and peripheral T-cells.
T34866L	Thymocartin Acetate Thymocartin Acetate(85466-18-8 Free base)
	Thymocartin Acetate 是天然存在的胸腺因子（胸腺生成素）的32-35片段，对酶降解具有抑制作用。Thymocartin Acetate 具有治疗免疫缺陷病的潜力。
TP1855	Moth Cytochrome C (MCC) (88-103) Moth Cytochrome C (MCC) 88-103
	Moth Cytochrome C (MCC) (88-103), derived from the carboxyl terminus of moth cytochrome c, induces positive selection of TCR transgenic thymocytes.This peptide is derived from the carboxyl terminus of moth cytochrome c. Thymic positive and negative select
T82507	Ecleralimab CSJ-117,NVP-CSJ117
	Ecleralimab (CSJ-117; NVP-CSJ117) 是一种 Fab-IgG1-λ2 类型的单克隆抗体，专一性靶向胸腺基质淋巴生成素（TSLP）。该抗体主要采用 CHO（Chinese Hamster Ovary）细胞表达系统生产。
T35513	13C15-Nivalenol 13C15-Nivalenol
	13C15-Nivalenol is intended for use as an internal standard for the quantification of nivalenol by GC- or LC-MS. Nivalenol is a trichothecene mycotoxin that has been found inFusarium.1It is lethal to mice (LD50= 6.9 mg/kg).2Nivalenol (5, 10, and 15 mg/kg) also induces thymic, splenic, and Peyer's patch cell apoptosis in mice.3 1.Yang, Z., Concannon, J., Ng, K.S., et al.Tetrandrine identified in a small molecule screen to activate mesenchymal stem cells for enhanced immunomodulationSci. Rep.63026...
T11449	Golotimod hydrochloride (229305-39-9 free base) Golotimod hydrochloride,Gamma-D-glutamyl-L-tryptophan hydrochloride,SCV 07 hydrochloride	STAT	JAK/STAT signaling; Stem Cells
	Golotimod (SCV 07) hydrochloride 是一种免疫调节肽，具抗菌活性，能显著提升抗结核疾病研究效果。该化合物通过刺激胸腺和脾细胞增殖、改善巨噬细胞功能，展现其生物调节能力。此外，Golotimod hydrochloride 通过抑制STAT3信号传导，有效调节接受放疗或与顺铂联用治疗动物模型中的口腔粘膜炎持续时间和严重程度。还显示出对研究复发性生殖器单纯疱疹病毒 2 型 (HSV-2) 具有潜在应用价值。
T36383	L-Thyroxine-13C9,15N L-Thyroxine-13C9,15N
	L-Thyroxine-13C9,15N is intended for use as an internal standard for the quantification of L-thyroxine by GC- or LC-MS. L-Thyroxine is a synthetic form of the thyroid hormone thyroxine. In vivo, L-thyroxine (0.9 and 2.7 μg) inhibits synthesis and release of thyrotropin induced by thyrotropin-releasing hormone from the anterior pituitary in mice. It also reverses decreases in levels of circulating thymic serum factor (FTS) and the number of T rosette-forming cells in an old age-induced mouse mode...

化合物

Cat.No: T34867

Synonym: Thymic humoral factor gamma 2

Cat.No: T16832

Target: ROR

Splenopentin diacetate

Cat.No: T21459

Synonym: Thymopoietin III pentapeptide (32-36),SP5,Splenopentin Acetate,醋酸脾脏五肽,Splenin pentapeptide (32-36),Arg-lys-glu-val-tyr

Target: Others

Influenza HA 126-138 acetate

Cat.No: TP1735L

Synonym: Influenza HA 126-138 acetate(207349-63-1 free base)

Target: Others

Cat.No: TP2324

Target: Immunology/Inflammation related

Cat.No: T34866

Synonym: Thymocartinum,TP 4,Thymopoietin II (32-35),RGH 0206

Thymosin β4 acetate(75591-33-4 free base)

Cat.No: TP2319

Target: Autophagy

Cat.No: T11449L

Synonym: Gamma-D-glutamyl-L-tryptophan,SCV 07

Target: Antibiotic

Thymus factor X

Cat.No: TP1030

Synonym: TFX-Jelfa,胸腺因子X

Influenza HA (126-138)

Cat.No: TP1735

Synonym: Influenza HA 126-138

Thymocartin Acetate

Cat.No: T34866L

Synonym: Thymocartin Acetate(85466-18-8 Free base)

Moth Cytochrome C (MCC) (88-103)

Cat.No: TP1855

Synonym: Moth Cytochrome C (MCC) 88-103

Cat.No: T82507

Synonym: CSJ-117,NVP-CSJ117

13C15-Nivalenol

Cat.No: T35513

Synonym: 13C15-Nivalenol

Golotimod hydrochloride (229305-39-9 free base)

Cat.No: T11449

Synonym: Golotimod hydrochloride,Gamma-D-glutamyl-L-tryptophan hydrochloride,SCV 07 hydrochloride

Target: STAT

L-Thyroxine-13C9,15N

Cat.No: T36383

Synonym: L-Thyroxine-13C9,15N

Cat. No.	Product Name	Target	Signaling Pathways
T3S0717	Thymol 2-isopropyl-5-methylphenol,Pseudoaspidin,Thymic Acid,Thyme Camphor,百里酚	Antibacterial	Microbiology/Virology
	Thymol (Pseudoaspidin) 是从唇形科植物以及如马鞭草科、玄参科、毛茛科等其他植物中分离出来的精油中的主要单萜酚。它具有抗炎、抗菌、抗氧化和抗真菌作用。
T7203	Oglufanide 奥谷法奈,L-Glutamyl-L-tryptophan,H-Glu-Trp-OH	VEGFR; HCV Protease; Endogenous Metabolite	Angiogenesis; Metabolism; Microbiology/Virology; Proteases/Proteasome; Tyrosine Kinase/Adaptors
	Oglufanide (H-Glu-Trp-OH) 是一种从小牛胸腺中分离出来的二肽免疫调节剂，可抑制血管内皮生长因子，可刺激细胞内细菌感染和对丙型肝炎病毒的免疫反应。
T37705	1,2,4-Trihydroxybenzene Benzene-1,2,4-triol	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	1,2,4-Trihydroxybenzene (Benzene-1,2,4-triol) 是咖啡豆烘焙的副产品，是在小鼠、阿拉伯咖啡中发现的。1,2,4-Trihydroxybenzene 是一种苯三醇，它能增加大鼠胸腺淋巴细胞内的Ca2+浓度。
T75661	Thymopentin acetate
	Thymopentin acetate为胸腺皮质及髓质上皮细胞主要分泌的生物活性肽，是一有效免疫调节剂，具有极短的血浆半衰期(30秒)，能促进自人类胚胎干细胞生成T细胞群。

天然产物

Cat.No: T3S0717

Synonym: 2-isopropyl-5-methylphenol,Pseudoaspidin,Thymic Acid,Thyme Camphor,百里酚

Target: Antibacterial

Cat.No: T7203

Synonym: 奥谷法奈,L-Glutamyl-L-tryptophan,H-Glu-Trp-OH

Target: VEGFR, HCV Protease, Endogenous Metabolite

1,2,4-Trihydroxybenzene

Cat.No: T37705

Synonym: Benzene-1,2,4-triol

Target: Calcium Channel

Thymopentin acetate

Cat.No: T75661

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