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Search Results for " staphylococci "

24

抑制剂 & 化合物

6

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T40475	Ceftobiprole medocaril BAL5788,头孢比普酯	Antibacterial	Microbiology/Virology
	Ceftobiprole medocaril (BAL5788) 是 Ceftobiprole 的前药。Ceftobiprole 是一种广谱的头孢菌素，对耐甲氧西林金黄色葡萄球菌具有活性。
TQ0077	Ceftobiprole Ro 63-9141,BAL 9141,头孢吡普	Antibacterial	Microbiology/Virology
	Ceftobiprole (Ro 63-9141) 是一种广谱头孢菌素，对甲氧西林耐受的金黄色葡萄球菌的MIC90值为 2 μg/mL。
T15237	Eperezolid PNU-100592	Antibacterial; Antibiotic	Microbiology/Virology
	Eperezolid (PNU-100592) 是一种在体外表现出良好抑制活性的恶唑烷酮类抗生素。
T0985	Oxacillin sodium salt 苯唑西林,Oxacillin sodium,Oxabel	Antibacterial; Antibiotic	Microbiology/Virology
	Oxacillin sodium salt (Oxabel) 是一种青霉素类的窄谱β-内酰胺抗生素，用于耐药葡萄球菌感染。
T11427	Antibacterial compound 2	Antifungal	Microbiology/Virology
	Antibacterial compound 2 是一种有效的抗菌剂，对许多人类兽医病原体有效，对多重耐药葡萄球菌、肠球菌和链球菌，以及厌氧菌有抑制作用。
T1312	Nafcillin sodium monohydrate CL 8491,萘夫西林钠,nafcillin sodium	Antibacterial; Antibiotic	Microbiology/Virology
	Nafcillin sodium monohydrate (CL 8491) 是一种抗生素，是可逆的β-lactamase 抑制剂。它用于治疗由耐青霉素的葡萄球菌菌株引起的感染。
T14134	Afabicin AFN-1720,Debio 1450	Antibacterial	Microbiology/Virology
	Afabicin is the prodrug of Debio1452. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci.
T27818	Levonadifloxacin Arginine Salt WCK 771,WCK-771A,WCK 771A,WCK-771,WCK771A,WCK771
	Levonadifloxacin, a broad-spectrum fluoroquinolone antibiotic, is used potentially for the treatment of staphylococci.
T63718	Afabicin disodium
	Afabicin (Debio 1450) 是一种 Debio1452 的前体药物，能够抵抗葡萄球菌 staphylococci，对其他的革兰氏阳性菌和阴性菌无明显作用。其中 Debio1452 是一种 FabI 抑制剂，对葡萄球菌中的脂肪合成具有抑制作用。
T10579	BO3482	Others	Others
	BO3482 is an antimicrobial compound and can inhibit the growth of methicillin-resistant Staphylococci (MIC90: 6.25 mg/mL).
T21440	Nafcillin Unipen,Nallpen
	Nafcillin sodium, a narrow-spectrum beta-lactam antibiotic of the penicillin class, is used to treat infections caused by Gram-positive bacteria, in particular, species of staphylococci that are resistant to other penicillins.
T61951	Oxacillin
	Oxacillin 是口服有效的合成青霉素。Oxacillin 对葡萄球菌和其他革兰氏阳性病原体具有良好的杀菌 (bactericidal) 活性。
T26162	Rubradirin
	Rubradirin is an antibiotic with a complex chemical structure that is active vs. methicillin resistant staphylococci. It is a selective enzymatic peptide initiation inhibitor.
T38913	Furaltadone L-tartrate Furaltadone L-tartrate,Altafur L-tartrate
	Furaltadone L-tartrate (Altafur L-tartrate), a nitrofuran antimicrobial agent, is potentially useful for researching Salmonella enteritidis infections in chickens. It demonstrates both inhibitory and bactericidal properties against Staphylococci in vitro.
T26984	Cetocycline hydrochloride Chelocardin Hydrochloride,Cetotetrine Hydrochloride,Cetocycline HCl
	Cetocycline hydrochloride is an antibacterial biochemical. It is active against many clinical isolates of aerobic gram-negative bacilli, but is less active against staphylococci, and has no activity against Pseudomonas.
T40662	Isepamicin Sch 21420
	Isepamicin (Sch 21420) is a potent aminoglycoside antibacterial compound with enhanced efficacy against strains harboring type I 6'-acetyltransferase. Its antibacterial spectrum encompasses Enterobacteriaceae and staphylococci, while exhibiting resistance against anaerobes, Neisseriaceae, and streptococci. Moreover, Isepamicin displays a robust concentration-dependent bactericidal effect, a prolonged post-antibiotic effect lasting several hours, and is capable of inducing adaptive resistance.
T21163	Cloxacillin Sodium BRL-1621 sodium salt,Ankerbin,Cloxapen,Austrastaph,BRL 1621 sodium salt
	Cloxacillin Sodium, a chlorinated derivative of Oxacillin, is a semi-synthetic antibiotic. Cloxacillin is used for the treatment of infections caused by species of staphylococci which produce beta-lactamase.
T74657	Balhimycin
	Balhimycin为一种源自Amycolatopsis sp.发酵产物的糖肽类抗生素，其展现出针对葡萄球菌和厌氧菌的显著抗菌效果。
T38972	Cefalonium hydrate
	Cefalonium hydrate is a first-generation β-lactam cephalosporin antibiotic commonly employed in the study of bovine mastitis induced by Gram-positive bacteria, particularly staphylococci. It demonstrates significant effectiveness in this research area.
T60883	Furaltadone
	Furaltadone 是一种硝基呋喃类药物，具有用于鸡感染肠炎沙门氏菌的潜力。Furaltadone 在体外对葡萄球菌具有抑制和杀菌作用。
T74821	Nemonoxacin
	Nemonoxacin (TG-873870) 是一种口服有效的广谱抗生素，对多种葡萄球菌、链球菌、肠球菌、淋病奈瑟菌和流感嗜血杆菌显示出强效的抑制活性。适用于研究细菌感染和社区获得性肺炎。
T28314	PD 117588 PD117588,PD-117588
	PD 117588 is a quinolone against bacterial isolates from cancer patients. PD 117558 has a broad antimicrobial spectrum with excellent activity against all Gram-positive isolates (including methicillin-resistant Staphylococcus aureus, coagulase-negative st
T72141	Ceftobiprole medocaril sodium 头孢比普酯钠盐,BAL5788 sodium
	Ceftobiprole medocaril (BAL5788) sodium 是 Ceftobiprole 的胃肠外前药。Ceftobiprole 是一种非肠道吡咯烷酮头孢菌素。Ceftobiprole 是一种广谱头孢菌素，对甲氧西林 (MRSA) 和耐万古霉素葡萄球菌 (VRSA) 和耐青霉素链球菌具有高水平的体外活性。Ceftobiprole 也抑制革兰氏阳性和革兰氏阴性病原体。
T14359	AVX 13616	Others	Others
	AVX 13616 shows the potent in vivo antibacterial activity of Avexa’s lead antibacterial candidate; particularly against drug-resistant Staphylococcus pathogens. IC50 value: 2-4 ug/ml (MICs) Target: antibacterial agent AVX13616 was as active as mupirocin i

化合物

Ceftobiprole medocaril

Cat.No: T40475

Synonym: BAL5788,头孢比普酯

Target: Antibacterial

Cat.No: TQ0077

Synonym: Ro 63-9141,BAL 9141,头孢吡普

Target: Antibacterial

Cat.No: T15237

Synonym: PNU-100592

Target: Antibacterial, Antibiotic

Oxacillin sodium salt

Cat.No: T0985

Synonym: 苯唑西林,Oxacillin sodium,Oxabel

Target: Antibacterial, Antibiotic

Antibacterial compound 2

Cat.No: T11427

Target: Antifungal

Nafcillin sodium monohydrate

Cat.No: T1312

Synonym: CL 8491,萘夫西林钠,nafcillin sodium

Target: Antibacterial, Antibiotic

Cat.No: T14134

Synonym: AFN-1720,Debio 1450

Target: Antibacterial

Levonadifloxacin Arginine Salt

Cat.No: T27818

Synonym: WCK 771,WCK-771A,WCK 771A,WCK-771,WCK771A,WCK771

Afabicin disodium

Cat.No: T63718

Cat.No: T10579

Target: Others

Cat.No: T21440

Synonym: Unipen,Nallpen

Cat.No: T61951

Cat.No: T26162

Furaltadone L-tartrate

Cat.No: T38913

Synonym: Furaltadone L-tartrate,Altafur L-tartrate

Cetocycline hydrochloride

Cat.No: T26984

Synonym: Chelocardin Hydrochloride,Cetotetrine Hydrochloride,Cetocycline HCl

Cat.No: T40662

Synonym: Sch 21420

Cloxacillin Sodium

Cat.No: T21163

Synonym: BRL-1621 sodium salt,Ankerbin,Cloxapen,Austrastaph,BRL 1621 sodium salt

Cat.No: T74657

Cefalonium hydrate

Cat.No: T38972

Cat.No: T60883

Cat.No: T74821

Cat.No: T28314

Synonym: PD117588,PD-117588

Ceftobiprole medocaril sodium

Cat.No: T72141

Synonym: 头孢比普酯钠盐,BAL5788 sodium

Cat.No: T14359

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T3982	Vulpinic Acid 狐衣酸,Vulpic acid,Pulvinic acid methyl ester	Others	Others
	Vulpinic Acid (Pulvinic acid methyl ester) 是地衣代谢物，可降低人脐静脉内皮细胞 (HUVEC) 中 H2O2诱导的ROS，氧化应激和氧化应激相关损伤，可作用于厌氧菌、葡萄球菌及肠球菌。它对脉粥样硬化的研究具有潜在的价值。
T16542	Piromidic acid 吡咯酸,吡乙酸三氮萘	Antibacterial; Antibiotic	Microbiology/Virology
	Piromidic acid 是一种抗菌剂。它对革兰氏阴性菌和葡萄球菌具有活性，可研究肠道，泌尿和胆道感染。
T8148	Mupirocin calcium hydrate 莫匹罗星钙,Mupirocin calcium	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Mupirocin calcium hydrate 是从Pseudomonas fluorescens 中分离得到的，一种有口服活性的抗生素。它可逆地抑制异亮氨酸转移RNA，并抑制细菌蛋白和RNA 的合成起到抗菌作用。
T1465	Mupirocin Pseudomonic acid,莫匹罗星,BRL-4910A	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Mupirocin (BRL-4910A) 是从Pseudomonas fluorescens 中分离得到的一种有口服活性的抗生素。它可逆地抑制异亮氨酸转移RNA，并抑制细菌蛋白和RNA 的合成起抗菌作用。
T0819	Spiramycin Espiramicin,螺旋霉素,Sequamycin,Rovamycin,Provamycin,Formacidine	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Spiramycin (Rovamycin) 是一种由安博链霉菌产生的大环内酯类抗生素，具有抗细菌和弓形虫活性，并具有抗寄生虫作用。它由 16 个内酯环组成，其上附着 mycaminose，forosamine 和 mycarose 三种糖。
T20675	Sisomicin Rickamicin,Siseptin
	Sisomicin is a broad-spectrum aminoglycoside antibiotic isolated from Micromonospora inyoensis. It is highly active against staphylococci.

天然产物

Cat.No: T3982

Synonym: 狐衣酸,Vulpic acid,Pulvinic acid methyl ester

Target: Others

Cat.No: T16542

Synonym: 吡咯酸,吡乙酸三氮萘

Target: Antibacterial, Antibiotic

Mupirocin calcium hydrate

Cat.No: T8148

Synonym: 莫匹罗星钙,Mupirocin calcium

Target: Others, Antibacterial, Antibiotic

Cat.No: T1465

Synonym: Pseudomonic acid,莫匹罗星,BRL-4910A

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T0819

Synonym: Espiramicin,螺旋霉素,Sequamycin,Rovamycin,Provamycin,Formacidine

Target: Antibacterial, Antibiotic, Parasite

Cat.No: T20675

Synonym: Rickamicin,Siseptin

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