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Search Results for " ssp "

Targets Recommended: Kisspeptin

25

抑制剂 & 化合物

3

天然产物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T31717	Etiguanfacine SSP-1871,SSP 1871 Etiguanfacine,SSP1871
	Etiguanfacine(SSP-1871) is a agonist of α2-adrenoreceptor.
T31363	Deferitazole magnesium FBS0701,FBS-0701,SSP-004184,SHP-602,SHP602,Deferitazole free base
	Deferitazole magnesium is a potential chelator for iron overload treatment.
TP1666L	Kisspeptin-10, rat acetate(478507-53-8 free base)	GPR; Kisspeptin	Endocrinology/Hormones; GPCR/G Protein
	Kisspeptin-10, rat acetate(478507-53-8 free base) 是啮齿动物 Kisspeptin 受体 (KISS1, GPR54) 的内源性配体。
T21559	OTSSP167 hydrochloride OTSSP 167 盐酸盐	MELK	PI3K/Akt/mTOR signaling
	OTSSP167 hydrochloride 是一种高效的，ATP 竞争性的MELK 抑制剂，其 IC50=0.41 nM。
T15179	DTSSP Crosslinker	Others	Others
	DTSSP Crosslinker 是一种可降解的 ADC linker，可用于合成抗体-药物偶联物 (ADCs)。
TP1896L1	Kisspeptin 234 acetate(1145998-81-7 free base)	GPR; Kisspeptin	Endocrinology/Hormones; GPCR/G Protein
	Kisspeptin 234 acetate(1145998-81-7 free base) 是Kisspeptin 受体 (KISS1, GPR54) 拮抗剂；是Kisspeptin-10 类似物。它抑制 Kisspeptin-10 对磷酸肌醇 (IP) (IC50 = 7 nM) 的刺激和促性腺激素释放激素 (GnRH) 的释放。
T1759	OTSSP167 MELK inhibitor,OTS167	MELK	PI3K/Akt/mTOR signaling
	OTSSP167 (OTS167) 是一种高效的，ATP 竞争性的 MELK 抑制剂，其 IC50=0.41 nM。
TP1345	Kisspeptin-10, human (TFA)(374675-21-5,FREE)	GPR; Kisspeptin	Endocrinology/Hormones; GPCR/G Protein
	Kisspeptin-10, human (TFA)(374675-21-5,FREE) 是一种有效的血管收缩剂和血管生成抑制剂。 Kisspeptin-10，人类 TFA 通过其受体 GPR54 充当肿瘤转移抑制因子。 Kisspeptin-10-GPR54系统在胚胎肾发育中发挥重要作用。 Kisspeptin-10/GPR54 信号通过 NFATc4 介导的 BMP2 表达诱导成骨细胞分化
T17506	Azido-PEG3-SSPy	Others	Others
	Azido-PEG3-SSPy is a three-unit cleavable polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
T40162	Acid-C3-SSPy Acid-C3-SSPy
	Acid-C3-SSPy is a cleavable DBA-DM4 linker used in the synthesis of DBA-DM4 , a drug-linker conjugate for ADC.
TP2010	Kisspeptin 10 (dog)
	Endogenous ligand for the canine KISS1 receptor (Kisspeptin receptor or GPR54). Stimulates section of luteinizing hormone, follicle stimulating hormone and estradiol in vivo.
T75774	Kisspeptin-54(human) TFA
	Kisspeptin-54(human) TFA (Metastin(human) TFA) 是一种 Kisspeptin 受体 (KISS1，GPR54) 的内源性配体，以高亲和力结合大鼠和人类 GPR54受体，其Ki 值分别为 1.81 nM 和 1.45 nM。Kisspeptin-54(human) TFA 可抑制肿瘤转移并刺激促性腺激素分泌。
T76339	Kisspeptin 13
	Kisspeptin 13 是一种 GPR54和 GnRH 受体激活剂，是一种内源性的活性异构体。Kisspeptin 13 能增强记忆，可用于阿尔茨海默病的研究。
T17640	Boc-amino-PEG3-SSPy	Others	Others
	Boc-amino-PEG3-SSPy is a cleavable 3-unit polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker employed for synthesizing ADCs[1].
T77859	bisSP1
	BisSP1为一种ADCs linker，具备抗体活性分子偶联功能。
T75745	Kisspeptin-10, human TFA
	Kisspeptin-10, human TFA为一种有效的血管收缩剂及血管生成抑制剂，通过其受体GPR54抑制肿瘤转移。Kisspeptin-10-GPR54系统对胚胎肾脏发展具有关键影响，而Kisspeptin-10/GPR54信号则通过NFATc4介导的BMP2表达促进成骨细胞分化。
TP2005	Kisspeptin-54(human) Metastin (human)
	Potent endogenous ligand of the kisspeptin receptor (KISS1, GPR54). Binds with high affinity to rat and human KISS1 receptors with Ki values of 1.80 and 1.45 nM respectively. Inhibits chemotaxis, invasion and metastasis of human melanomas and breast carci
T39500	Acid-PEG3-SSPy Acid-PEG3-SSPy
	Acid-PEG3-SSPy is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T78106	Kisspeptin 234 TFA
	Kisspeptin 234 TFA，作为一种十肽，是kisspeptin受体（KISS1, GPR54）的拮抗剂，并且是Kisspeptin 10的类似物。
TP1896	Kisspeptin 234
	Kisspeptin 234 is a kisspeptin receptor (KISS1, GPR54) antagonist; kisspeptin-10 analog. Inhibits kisspeptin-10 stimulation of inositol phosphate (IP) (IC50 = 7 nM) and release of gonadotrophin-releasing hormone (GnRH).
TP1666	Kisspeptin-10, rat
	Kisspeptin-10, rat is an Endogenous ligand for the rodent kisspeptin receptor (KISS1, GPR54).
TP1396	Kisspeptin-10, human
	Kisspeptin-10, human is an effective vasoconstrictor and inhibitor of angiogenesis.
T35794	Kisspeptin-54 (human) (trifluoroacetate salt)
	Kisspeptin-54 is a peptide ligand of the orphan G protein-coupled receptor GPR54 (Kis = 1.81 and 1.45 nM for rat and human receptors, respectively).1 It is a 54 amino acid peptide encoded by the metastasis suppressor gene KISS-1. Kisspeptin-54 induces calcium mobilization in CHO-K1 cells expressing rat and human receptors (EC50s = 1.39 and 5.47 nM, respectively). It also induces arachidonic acid release in CHO cells expressing rat and human GPR54 in a concentration-dependent manner. Kisspeptin-5...
T83666	Kisspeptin-10 (zebrafish) TFA Tyr-Asn-Leu-Asn-Ser-Phe-Gly-Leu-Arg-Tyr-NH2,Kp-10
	Kisspeptin-10是一种在斑马鱼的大脑、卵巢和睾丸中表达的神经肽，参与性腺发育和类固醇表达。在10 ng/ml的浓度下使用时，能提高孤立的斑马鱼卵巢滤泡中编码黄体生成素(luteinizing hormone, Lh)受体，以及孕酮受体a (Progestin receptor a, Pra)和Prb的mRNA水平。在0.1和1 µg/g的剂量下给予时，Kisspeptin-10能在雌性金鱼中增加黄体生成素的血清水平，但在雄性金鱼中则不会。
T75839	Kisspeptin-10, rat TFA
	Kisspeptin-10, rat TFA 作为有效的血管收缩剂及血管生成抑制剂，为GPR54 (亦称KISS1) 亲吻蛋白受体的配体。此外，Kisspeptin-10, rat TFA 能降低Methotrexate引起的生殖毒性并显示出抗氧化潜力。

化合物

Cat.No: T31717

Synonym: SSP-1871,SSP 1871 Etiguanfacine,SSP1871

Deferitazole magnesium

Cat.No: T31363

Synonym: FBS0701,FBS-0701,SSP-004184,SHP-602,SHP602,Deferitazole free base

Kisspeptin-10, rat acetate(478507-53-8 free base)

Cat.No: TP1666L

Target: GPR, Kisspeptin

OTSSP167 hydrochloride

Cat.No: T21559

Synonym: OTSSP 167 盐酸盐

Target: MELK

DTSSP Crosslinker

Cat.No: T15179

Target: Others

Kisspeptin 234 acetate(1145998-81-7 free base)

Cat.No: TP1896L1

Target: GPR, Kisspeptin

Cat.No: T1759

Synonym: MELK inhibitor,OTS167

Target: MELK

Kisspeptin-10, human (TFA)(374675-21-5,FREE)

Cat.No: TP1345

Target: GPR, Kisspeptin

Azido-PEG3-SSPy

Cat.No: T17506

Target: Others

Cat.No: T40162

Synonym: Acid-C3-SSPy

Kisspeptin 10 (dog)

Cat.No: TP2010

Kisspeptin-54(human) TFA

Cat.No: T75774

Cat.No: T76339

Boc-amino-PEG3-SSPy

Cat.No: T17640

Target: Others

Cat.No: T77859

Kisspeptin-10, human TFA

Cat.No: T75745

Kisspeptin-54(human)

Cat.No: TP2005

Synonym: Metastin (human)

Acid-PEG3-SSPy

Cat.No: T39500

Synonym: Acid-PEG3-SSPy

Kisspeptin 234 TFA

Cat.No: T78106

Cat.No: TP1896

Kisspeptin-10, rat

Cat.No: TP1666

Kisspeptin-10, human

Cat.No: TP1396

Kisspeptin-54 (human) (trifluoroacetate salt)

Cat.No: T35794

Kisspeptin-10 (zebrafish) TFA

Cat.No: T83666

Synonym: Tyr-Asn-Leu-Asn-Ser-Phe-Gly-Leu-Arg-Tyr-NH2,Kp-10

Kisspeptin-10, rat TFA

Cat.No: T75839

Cat. No.	Product Name	Target	Signaling Pathways
TN5959	30-Oxopseudotaraxasterol 3β-Hydroxytaraxaster-20-en-30-al
	30-Oxopseudotaraxasterol is a natural product from Pulicaria canariensis ssp. lanata.
TN2679	2,2-Dimethyl-6-phenylpyrano[3,4-b]pyran-8-one	Others	Others
	2,2-Dimethyl-6-phenylpyrano[3,4-b]pyran-8-one is a natural product from the metabolites of Hypericum revolutum ssp.
T83555	(3ξ,4ξ,5ξ,6ξ,7ξ,11ξ)-3,6-Dihydroxy-8-oxo-9-eremophilene-12-oic acid
	(3ξ,4ξ,5ξ,6ξ,7ξ,11ξ)-3,6-Dihydroxy-8-oxo-9-eremophilene-12-oic acid 是与苹果果斑病相关的Alternaria alternata ssp. tenuissima 新分离的植物毒素。

天然产物

30-Oxopseudotaraxasterol

Cat.No: TN5959

Synonym: 3β-Hydroxytaraxaster-20-en-30-al

2,2-Dimethyl-6-phenylpyrano[3,4-b]pyran-8-one

Cat.No: TN2679

Target: Others

(3ξ,4ξ,5ξ,6ξ,7ξ,11ξ)-3,6-Dihydroxy-8-oxo-9-eremophilene-12-oic acid

Cat.No: T83555

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02390	SSPA Protein, E. coli, Recombinant (His) ssp,pog	E. coli	E. coli
	Stringent starvation protein A (ssPA), a member of the GST superfamily, is an RNA polymerase-associated transcriptional activator for the lytic development of phage P1 and is essential for stationary phase-induced acid tolerance of E. coli. It indicates that the flexible regions are not critical for SspA function, whereas the surface pocket is important for both transcriptional activation of the phage P1 late promoter and acid resistance of E. coli. SspA is known to be implicated in survival dur...
TMPJ-01295	SENP7 Protein, Human, Recombinant SSP2,KIAA1707,Sentrin-Specific Protease 7,SUSP2,SUM...	Human	E. coli
	Sentrin-Specific Protease 7 (SENP7) acts as a SUMO-2/3-specific protease. SENP7 is likely to regulate the metabolism of poly-SUMO-2/3 rather than SUMO-1 conjugation in vivo. SENP7 has a restricted substrate specificity, and displaying paralogue-specific isopeptidase activity. The C-terminal catalytic domain of SENP7 depolymerized poly-SUMO-2 chains but does not have activity against poly-SUMO-1 chains. SENP7 also had isopeptidase activity against di-SUMO-2- and SUMO-2-modified RanGAP1 (Ran GTPas...
TMPH-00681	ssPB Protein, E. coli O157:H7, Recombinant (His)	E. coli	E. coli
	Seems to act in concert with SspA in the regulation of several proteins during exponential and stationary-phase growth. The exact function of SspB is not yet known.
TMPH-02553	BSSP-4 Protein, Mouse, Recombinant (His) Serine protease 26,Brain-specific serine protease 4,BSSP...	Mouse	E. coli
	N/A. BSSP-4 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.9 kDa and the accession number is Q9ER10.
TMPJ-01320	BSSP-4 Protein, Human, Recombinant (His) BSSP4,Tryptase ε,Serine Protease 26,BSSP-4...	Human	HEK293 Cells
	Brain-Specific Serine Protease 4 (BSSP-4) is a serine protease that preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. BSSP-4 is expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal lung, but scarce in adult lung and expressed at low levels in placenta, pancreas, prostate and thyroid gland. BSSP-4 belongs to the peptidase S1 family and related to trypsin, referentially hydrolyzing substrates after a...
TMPH-02395	Lassa virus (strain GA391) GPC Protein (His)	LASV	E. coli
	class I viral fusion protein that directs fusion of viral and host endosomal membranes, leading to delivery of the nucleocapsid into the cytoplasm. Membrane fusion is mediated by irreversible conformational changes induced upon acidification in the endosome.; Stable signal peptide (SSP): cleaved and functions as a signal peptide. In addition, it is also retained as the third component of the GP complex. The SSP is required for efficient glycoprotein expression, post-translational maturation clea...
TMPH-02396	Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) Z Protein (His)	LASV	E. coli
	Plays a crucial role in virion assembly and budding. Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L. Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP. Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins in...

重组蛋白

SSPA Protein, E. coli, Recombinant (His)

Cat.No: TMPY-02390

Species: E. coli

Expression System: E. coli

SENP7 Protein, Human, Recombinant

Cat.No: TMPJ-01295

Species: Human

Expression System: E. coli

ssPB Protein, E. coli O157:H7, Recombinant (His)

Cat.No: TMPH-00681

Species: E. coli

Expression System: E. coli

BSSP-4 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02553

Species: Mouse

Expression System: E. coli

BSSP-4 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01320

Species: Human

Expression System: HEK293 Cells

Lassa virus (strain GA391) GPC Protein (His)

Cat.No: TMPH-02395

Species: LASV

Expression System: E. coli

Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) Z Protein (His)

Cat.No: TMPH-02396

Species: LASV

Expression System: E. coli

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