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4

抑制剂 & 化合物

28

天然产物

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Cat. No. Product Name Target Signaling Pathways
T124356 Sativanone

Sativanone 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124356。
T81471 Phytoene desaturase-IN-2

PDS-IN-1为Oryza sativa中八氢番茄红素去饱和酶(OsPDS)的抑制剂,具备除草效能。
T35434 β-Cembrenediol

β-Cembrenediol (β-CBT) is a natural product from tobacco plants that is found in cigarette smoke condensate. β-CBT inhibits induction of the early antigen of Epstein-Barr virus (EA-EBV) by 12-O-tetradecanoylphorbol-13-acetate (TPA) in vitro (IC50 = 21.9 μM). It inhibits tumor promoting effects of TPA on 7,12-demethylbenz[a]anthracene-induced papilloma formation in vivo. β-CBT is also released into soil by flue-cured tobacco plants and exerts autotoxicity as well as phytotoxic activity against L....
T37743 N-octadecanoyl-L-Homoserine lactone

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gener...

化合物

Sativanone
Cat.No: T124356
Synonym:
Target:
Phytoene desaturase-IN-2
Cat.No: T81471
Synonym:
Target:
β-Cembrenediol
Cat.No: T35434
Synonym:
Target:
N-octadecanoyl-L-Homoserine lactone
Cat.No: T37743
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T4088 Thymoquinone

NSC 2228,Thymoquinon,百里醌

BCL Apoptosis
Thymoquinone (NSC 2228) 是一种分离自 N. sativa 中的天然产物,具有抗炎、抗氧化、抗癌、抗肿瘤活性和保肝作用。
T5667 Octyl acetate

Acetic acid octyl ester,醋酸辛酯

Others Others
Octyl acetate (Acetic acid octyl ester) 是一种野生欧洲防风草 (Pastinaca sativa) 的管子或油管中精油的主要成分,具有抗氧化作用。
TN5455 6-Hydroxyisosativan

6-Hydroxyisosativan 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5455,CAS号为 2172624-69-8。
TN5543 Isosativanone

Isosativanone 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5543,CAS号为 82829-55-8。
TN5480 (-)-Sativan

(-)-Sativan is a phytoalexin.
TN4327 Isosativan

三叶草

Others Others
Isosativan, sativan and vestitol are isoflavan phytoalexins.
TN4953 Sativan

三叶草

Antifection Microbiology/Virology
Sativan possesses a broad spectrum of antimicrobial activity against bacteria and phytopathogenic fungi, it exhibits antituberculosis activity against Mycobacterium tuberculosis H37Rv, with the MIC value of 50 ug/mL.
T3S2340 Usaramine

(15E)-Retrorsine,Mucronatine,光萼野百合碱,NISTC15503874

Others; Antibacterial Microbiology/Virology; Others
Usaramine (Mucronatine) 是从 Crolatalaria pallida 种子中分离得到的一种吡咯里嗪类生物碱。它对 Lactuca sativa var 具有植物毒性。
TN7126 N-Vanillyloctanamide

Others Others
N-Vanillyloctanamide 是一种来自 Capsicum annuum L. var. 果实的辣椒素。年鉴。 N-Vanillyloctanamide 减少 Lactuca sativa 幼苗的自由基长度,这种抑制是剂量依赖性的。
T10668 Camalexin

Reactive Oxygen Species; ROS; Antibacterial; Antifungal Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
Camalexin 是从Camelina sativa 和Arabidopsis 中分离出来的一种植物抗毒素,可诱导活性氧的产生,具有抗菌、抗真菌、抗增殖和抗癌活性。
T5607 Geranyl acetate

Apoptosis; Others Apoptosis; Others
Geranyl acetate 是一种由香叶醇衍生而来的无环单萜烯酯,可诱导细胞凋亡。它具有香味,被广泛用于化妆品行业。
T8266 (R)-Citronellol

D-Citronellol,(R)-(+)-β-Citronellol,(R)-3,7-二甲基-6-辛烯醇

Others; Endogenous Metabolite Metabolism; Others
(R)-Citronellol ((R)-(+)-β-Citronellol) 是一种存在于天竺葵精油中的醇单萜。它抑制肥大细胞的脱颗粒,并且不影响咖啡因的苦味感。它能够用于装饰性化妆品,盥洗用品以及非化妆品中。
TN7252 Olivetolic acid

2,4-Dihydroxy-6-pentylbenzoic acid

Antibiotic Microbiology/Virology
Olivetolic acid (OLA)  是一种来自大麻中大麻素的前体,在Dravet综合征的小鼠模型中显示抗惊厥活性。Olivetolic acid 具有潜在的抗菌活性。
T3368 Alpha-Hederin

α常春藤皂甙,Helixin,Tauroside E,α-Hederin,Hederoside C

Apoptosis; Others Apoptosis; Others
Alpha-Hederin (Tauroside E) 是存在于黑种草种子中的一种单桥糖三萜皂苷,具有抗肿瘤作用。它可通过激活线粒体依赖性途径抑制胃癌细胞增殖,诱导凋亡,并有活性氧生成和谷胱甘肽减少。
T19238 Tricin 7-O-glucuronide

Chrysin-7-O-β-D-glucuronide

Others Others
Tricin 7-O-glucuronide is a flavonoid from Alfalfa (Medicago sativa L.).
TN6418 7-Methoxyneochamaejasmine A

7-Methoxyneochamaejasmine A has a strong inhibitory effect on Festuca rubra L. and Medicago sativa seedlings.
TN3581 Cannabivarin

Others Others
Cannabivarin is a natural product from Cannabis sativa.
T82784 Cannflavin B

Canniflavone

Cannflavin B,一种从Cannabis sativa L. 分离得到的异戊二烯化黄酮,表现出抗炎活性。
TN2574 10-O-Ethylcannabitriol

Others Others
10-O-Ethylcannabitriol is a natural product from Cannabis sativa L.
T82783 Cannflavin C

Cannaflavin C (compound 5) 是从大麻提取的化合物,具有抗氧化活性。
TMA0379 Cannabisin D

Others Others
Cannabisin D is a natural product from Cannabis sativa L.
TN4249 Ilicol

Others Others
Pinocembrin and Ilicol inhibit root growth and show IC50 (root growth) values of 0.199, 14.68, 8.05, 7.69 mM, and 1.22, 2.90, 7.35, 8.07 mM, against P. miliaceum, A. sativa, L. sativa, and R. sativus, respectively. They reduce Allium cepa cell
T80656 Cannflavin A

Cannflavin A,源自大麻(Cannabis sativa L),具备抗癌、神经保护及抗炎活性。该化合物有效抑制Aβ1-42的聚集,并阻断犬尿氨酸-3-单加氧酶(KMO)的活性,进而通过caspase-3裂解途径激活细胞凋亡(apoptosis)。
TN3973 Epinodosin

Others Others
Epinodosin induces significant DNA damage to HepG2 cells in a time- and dose-dependent manner.Epinodosin has a biphasic, dose-dependent effect on root growth and a strong inhibitory effect on root hair development in Lactuca sativa L. seedlings.
T79980 Flaccidoside III

Glucosidase Metabolism
Flaccidoside III, 分离自黑种草(N. sativa)地上部分的一种类黄酮和三萜类化合物,具有抑制α-Glucosidase(IC50:256.7 μM)的活性,表现出潜在的抗氧化和抗糖尿病效应。
T36886 Pestalotin

Pestalotin is a fungal metabolite originally isolated from P. cryptomeriaecola with diverse biological activities. It induces reducing sugar release in embryoless rice endosperms when used at concentrations ranging from 3 to 100 mg/L and enhances growth of rice seedlings (O. sativa) when used in combination with gibberellin A3 at concentrations ranging from 30 to 500 mg/L. Pestalotin has antifungal activity, reducing the growth of C. albicans, C. neoformans, T. rubrum, and A. fumigatus (MICs = 1...
TN3979 Epiyangambin

PAFR GPCR/G Protein
Epiyangambin is a phytotoxic lignan, it shows inhibition of seed germination of Agrostis stolonifera cv. penncross (Poaceae) and inhibition of development of Lactuca sativa L. (Asteraceae) seedlings in a microassay using 24-well plates. Epiyangambin exhibits significant inhibition of the transformation of murine epidermal JB6 cells, with the IC50 value of 0.15 microg/mL. (+)-Epiyangambin also has anti-platelet aggregation activity.
T75576 Solidagonic acid

Solidagonic acid 通过促进异常单极纺锤体向双极纺锤体的转变来抑制 HSET 运动活动。Solidagonic acid 抑制裂殖酵母细胞死亡,并使有丝分裂纺锤体从单极形态逆转为双极形态。Solidagonic acid 对 Lactuca sativaL. 和 Lolium multiflorumLam 的幼苗具有生长抑制活性。

天然产物

Thymoquinone
Cat.No: T4088
Synonym: NSC 2228,Thymoquinon,百里醌
Target: BCL
Octyl acetate
Cat.No: T5667
Synonym: Acetic acid octyl ester,醋酸辛酯
Target: Others
6-Hydroxyisosativan
Cat.No: TN5455
Synonym:
Target:
Isosativanone
Cat.No: TN5543
Synonym:
Target:
(-)-Sativan
Cat.No: TN5480
Synonym:
Target:
Isosativan
Cat.No: TN4327
Synonym: 三叶草
Target: Others
Sativan
Cat.No: TN4953
Synonym: 三叶草
Target: Antifection
Usaramine
Cat.No: T3S2340
Synonym: (15E)-Retrorsine,Mucronatine,光萼野百合碱,NISTC15503874
Target: Others, Antibacterial
N-Vanillyloctanamide
Cat.No: TN7126
Synonym:
Target: Others
Camalexin
Cat.No: T10668
Synonym:
Target: Reactive Oxygen Species, ROS, Antibacterial, Antifungal
Geranyl acetate
Cat.No: T5607
Synonym:
Target: Apoptosis, Others
(R)-Citronellol
Cat.No: T8266
Synonym: D-Citronellol,(R)-(+)-β-Citronellol,(R)-3,7-二甲基-6-辛烯醇
Target: Others, Endogenous Metabolite
Olivetolic acid
Cat.No: TN7252
Synonym: 2,4-Dihydroxy-6-pentylbenzoic acid
Target: Antibiotic
Alpha-Hederin
Cat.No: T3368
Synonym: α常春藤皂甙,Helixin,Tauroside E,α-Hederin,Hederoside C
Target: Apoptosis, Others
Tricin 7-O-glucuronide
Cat.No: T19238
Synonym: Chrysin-7-O-β-D-glucuronide
Target: Others
7-Methoxyneochamaejasmine A
Cat.No: TN6418
Synonym:
Target:
Cannabivarin
Cat.No: TN3581
Synonym:
Target: Others
Cannflavin B
Cat.No: T82784
Synonym: Canniflavone
Target:
10-O-Ethylcannabitriol
Cat.No: TN2574
Synonym:
Target: Others
Cannflavin C
Cat.No: T82783
Synonym:
Target:
Cannabisin D
Cat.No: TMA0379
Synonym:
Target: Others
Ilicol
Cat.No: TN4249
Synonym:
Target: Others
Cannflavin A
Cat.No: T80656
Synonym:
Target:
Epinodosin
Cat.No: TN3973
Synonym:
Target: Others
Flaccidoside III
Cat.No: T79980
Synonym:
Target: Glucosidase
Pestalotin
Cat.No: T36886
Synonym:
Target:
Epiyangambin
Cat.No: TN3979
Synonym:
Target: PAFR
Solidagonic acid
Cat.No: T75576
Synonym:
Target:
TargetMol Loading
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