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13

抑制剂 & 化合物

11

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T32164	Insect repellent M 3535
	Insect repellent M 3535 is a bug repellant.
T8547	DCBA	Drug Metabolite	Metabolism
	DCBA 是驱虫剂 N-N-diethyl-meta-toluamide (DEET) 的代谢物。尿液中 DCBA 的浓度是评估 DEET 暴露程度的指标。
T25049	Allethrin	BCL; Caspase	Apoptosis; Proteases/Proteasome
	Allethrin 是拟除虫菊酯杀虫剂，是主要的驱蚊剂。它在大鼠睾丸癌细胞 (LC540) 中诱导氧化应激、细胞凋亡和钙释放。它还诱导 BCL-2、caspase-3 激活和细胞内钙的释放。
T16531	Picaridin 埃卡瑞丁,Lcaridin	Parasite	Microbiology/Virology
	Picaridin (Lcaridin) 是一种广谱节肢动物驱避剂，作用于蚊子和蜱的嗅觉感应，与其气味受体蛋白相互作用。
T0711L	Niclosamide olamine Niclosamide-olamine,Niclosamide Ethanolamine salt	Antibiotic; STAT; Parasite; Autophagy	Autophagy; JAK/STAT signaling; Microbiology/Virology; Stem Cells
	Niclosamide olamine (Niclosamide Ethanolamine salt) 是一种驱虫剂，可破坏寄生虫和动物模型中的线粒体代谢。它可逆地抑制雷帕霉素复合物的哺乳动物靶标，从而抑制STAT3(IC50为 0.25 μM) 并刺激自噬反应。
T0910	Terpin hydrate Terpin Monohydrate,cis-Terpin hydrate,萜品(水合结晶)	Others	Others
	Terpin hydrate 是一种祛痰药，可除去急慢性支气管炎病人的黏液。
T40613	Butopyronoxyl
	Butopyronoxyl is an insect repellent that can be mainly used to repel mosquitoes.
T20325	Butyl cinnamate NSC71966,NSC-71966,NSC 71966
	Butyl cinnamate is an agent of mosquito repellent.
T20807	Looplure ENT 33266,Pherocon CL,AI3-33266,Cabblemone,(Z)-7-Dodecen-1-olacetate
	Looplure is a chemosterilant, insect attractant and repellent.
T26538	AC-24,055 AC24,055,AC 24,055,AC-24055,AC24055,AC 24055
	AC-24,055 is a synthetic insect feeding repellent.
T20459	N,N-Diethyl-p-toluamide NSC 5686,NSC-5686,NSC5686
	N, N-Diethyl-p-toluamide is an agent of mosquito repellent.
T40833	ω-Hydroxy-DEET
	ω-Hydroxy-DEET, a significant metabolite of the insect repellent N-N-diethyl-meta-toluamide (DEET), exhibits anti-proliferative properties. DEET, renowned for being a spatial repellent and irritant, is frequently employed to deter mosquito contact.
T21464	Methiocarb Mercaptodimethur,Mesurol
	Methiocarb, a carbamate pesticide, is used as an insecticide, acaricide, bird repellent, and molluscicide. Methiocarb stimulates cholinergic by inhibiting reversibly acetylcholinesterase activity, making methiocarb a potent neurotoxin.

化合物

Insect repellent M 3535

Cat.No: T32164

Cat.No: T8547

Target: Drug Metabolite

Cat.No: T25049

Target: BCL, Caspase

Cat.No: T16531

Synonym: 埃卡瑞丁,Lcaridin

Target: Parasite

Niclosamide olamine

Cat.No: T0711L

Synonym: Niclosamide-olamine,Niclosamide Ethanolamine salt

Target: Antibiotic, STAT, Parasite, Autophagy

Cat.No: T0910

Synonym: Terpin Monohydrate,cis-Terpin hydrate,萜品(水合结晶)

Target: Others

Cat.No: T40613

Butyl cinnamate

Cat.No: T20325

Synonym: NSC71966,NSC-71966,NSC 71966

Cat.No: T20807

Synonym: ENT 33266,Pherocon CL,AI3-33266,Cabblemone,(Z)-7-Dodecen-1-olacetate

Cat.No: T26538

Synonym: AC24,055,AC 24,055,AC-24055,AC24055,AC 24055

N,N-Diethyl-p-toluamide

Cat.No: T20459

Synonym: NSC 5686,NSC-5686,NSC5686

ω-Hydroxy-DEET

Cat.No: T40833

Cat.No: T21464

Synonym: Mercaptodimethur,Mesurol

Cat. No.	Product Name	Target	Signaling Pathways
T3S0895	Spirostan-3-ol 剑麻皂苷元,Sarsaponin	Others	Others
	Spirostan-3-ol (Sarsaponin) 是 Sarsasapogenin 的立体异构体，是从植物材料中分离出来的类固醇糖苷，具有潜在的通过细胞凋亡的抗肿瘤活性。它可驱赶蜜蜂。
T7921	β-Cyclocitral beta-Cyclocitral,β-环柠檬醛	Others	Others
	β-Cyclocitral 是 β-胡萝卜素的挥发性氧化衍生物，是微囊藻特有的掠食性动物防御信号。它是一种强大的驱虫剂。它是主要的挥发性萜类化合物之一，可以上调防御基因的表达，从而增强过量光照 (EL) 的适应性。
T8256	piperitone 胡椒酮,3甲基-6-(1-甲基乙基)-2-环己烯-1-酮	Others	Others
	Piperitone 是强大的驱虫剂和抗食欲剂。它对 Cymbopogon schoenanthus(C. schoenanthus) 成虫、新产卵和新生幼虫有很大的毒性。
T13669	(E)-Cinnamamide trans-Cinnamamide,肉桂酰胺	Others	Others
	(E)-Cinnamamide (trans-Cinnamamide) 是 Cinnamamide 的活性较低的异构体，Cinnamamide 是一种有效的非致命化学驱虫剂，适用于减少鸟类害虫的损害。
T13449	(R)-(+)-Citronellal (+)-Citronellal,(R)-(+)-香茅醛	Others	Others
	(R)-(+)-Citronellal is a natural product isolated from citrus,used for insect repellent and antifungal properties.
TN6564	Palustrol
	Palustrol exhibits acaricidal, insecticidal, 'pesticidal' and/or arthropod repellent properties, may be useful sources of chemicals for the control of arthropods of medical, veterinary or agricultural importance.
TN5018	Sideroxylonal A	Others	Others
	Sideroxylonal A, isolated from the benzene extract of the leaves of Eucalyptus grandis, is a highly potent repellent.
TMA0478	Loliolid	Others	Others
	Loliolid is a germination inhibitor, and a repellent for ants (Atta cephalotes).It has cytostatic activity against carcnoma and leukaemia cells.
TN4026	Eucamalol	Others	Others
	Eucamolol exhibits significant repellent activity against Aedes albopictus, and inhibits its feeding as well as DEET, is effective repellent (75%) up to 3 h after exposure to mosquito.
TL0012	Shyobunone	Others	Others
	Shyobunone and isoshyobunone have insecticidal and repellant activity, they exhibit strong contact toxicity against Lasioderma serricorne (LS adults with LD50 values of 20.24 and 24.19 ug/adult, respectively; they are strongly repellent against Tribolium
T81991	Kaempferol-3-O-[2″,6″-di-O-E-p-coumaroyl]-β-D-glucopyranoside
	Kaempferol-3-O-[2″,6″-di-O-E-p-coumaroyl]-β-D-glucopyranoside为一种从O. dentata叶中提取的酰化坎氨酚葡萄糖苷，用作污染生物（蓝贻贝M. edulis）的驱虫剂。

天然产物

Cat.No: T3S0895

Synonym: 剑麻皂苷元,Sarsaponin

Target: Others

Cat.No: T7921

Synonym: beta-Cyclocitral,β-环柠檬醛

Target: Others

Cat.No: T8256

Synonym: 胡椒酮,3甲基-6-(1-甲基乙基)-2-环己烯-1-酮

Target: Others

(E)-Cinnamamide

Cat.No: T13669

Synonym: trans-Cinnamamide,肉桂酰胺

Target: Others

(R)-(+)-Citronellal

Cat.No: T13449

Synonym: (+)-Citronellal,(R)-(+)-香茅醛

Target: Others

Cat.No: TN6564

Sideroxylonal A

Cat.No: TN5018

Target: Others

Cat.No: TMA0478

Target: Others

Cat.No: TN4026

Target: Others

Cat.No: TL0012

Target: Others

Kaempferol-3-O-[2″,6″-di-O-E-p-coumaroyl]-β-D-glucopyranoside

Cat.No: T81991

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