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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TQ0219 |
MK-8033
|
c-Met/HGFR | Tyrosine Kinase/Adaptors |
MK-8033 是一种新型ATP 竞争性c-Met/Ron 双重抑制剂,对野生型c-Met 的IC50=1 nM,对c-Met N1100Y 的IC50=2.0 nM。 | |||
T61189 |
E7016
GPI 21016 |
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
E7016 (GPI 21016) (GPI 21016) 是一种口服有效的 PARP 抑制剂。E7016 可以通过抑制 DNA 修复来增强肿瘤细胞在体内外的放射敏感性。 | |||
T40066 |
SENP1-IN-3
SENP1-IN-3 |
||
SENP1-IN-3 is a distinct inhibitor of the deSUMOylation protease 1 (SENP1), designed to enhance tumor radiosensitivity. | |||
T40067 |
SENP1-IN-4
SENP1-IN-4 |
||
SENP1-IN-4, a distinct inhibitor of the deSUMOylation protease 1 (SENP1), is designed to enhance tumor radiosensitivity. | |||
T40068 |
SENP1-IN-1
SENP1-IN-1 |
||
SENP1-IN-1 is a distinct inhibitor of the deSUMOylation protease 1 (SENP1), designed to enhance tumor radiosensitivity. | |||
T40069 |
SENP1-IN-2
SENP1-IN-2 |
||
SENP1-IN-2, a distinct inhibitor of the deSUMOylation protease 1 (SENP1), is designed to enhance tumor radiosensitivity. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T10021 |
1-Methylxanthine
|
Endogenous Metabolite | Metabolism |
1-Methylxanthine 是咖啡因衍生物,是咖啡因和茶碱 (1,3-二甲基黄嘌呤,TP) 在人体尿代谢产物,能够提高肿瘤细胞的放射敏感性。 |