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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T25049 Allethrin

BCL; Caspase Apoptosis; Proteases/Proteasome
Allethrin 是拟除虫菊酯杀虫剂,是主要的驱蚊剂。它在大鼠睾丸癌细胞 (LC540) 中诱导氧化应激、细胞凋亡和钙释放。它还诱导 BCL-2、caspase-3 激活和细胞内钙的释放。
T37688 Cyfluthrin

Reactive Oxygen Species; Sodium Channel Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; NF-κB
Cyfluthrin 属于 II 型拟除虫菊酯,对多种昆虫都有杀灭效果。Cyfluthrin 是Nav1.8钠通道调节剂。它可应用于农业、兽医、杀虫剂、拟除虫菊酯和贮存产品等领域。
T13633 D-Phenothrin

(-)-trans-Phenothrin,右旋苯醚菊酯

Parasite Microbiology/Virology
D-Phenothrin ((-)-trans-Phenothrin) 是一种口服有效的 II 型合成拟除虫菊酯,广泛用于杀死昆虫,蚊子和人类虱子。它还用于兽医,保护农作物和控制动物上的害虫。
T27794 λ-Cyhalothrin

lambda-Cyhalothrin,Karate,λ-氯氟氰菊酯,Icon

Sodium Channel; Parasite Membrane transporter/Ion channel; Microbiology/Virology
λ-Cyhalothrin (Icon) 是广谱的 II 型合成除虫菊酯杀虫剂,含有 α-氰基,用于防治多种害虫。它是一种钠通道神经毒素,靶向中枢神经系统中神经元膜。
T9751 Transfluthrin

Others Others
Transfluthrin 是一种挥发性拟除虫菊酯类杀虫剂,针对昆虫电压门控钠通道 (VGSC)。
T9434 3-Phenoxybenzaldehyde cyanohydrin

三苯氧基苯甲醛,2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile

Others Others
3-Phenoxybenzaldehyde cyanohydrin (2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile) 是拟除虫菊酯类杀虫剂如氯菊酯的中间体。
T1332 Permethrin

氯菊酯,Transpermethrin,NRDC-143,Pounce,Ambush

Sodium Channel; Parasite Membrane transporter/Ion channel; Microbiology/Virology
Permethrin (NRDC-143) 是一种拟除虫菊酯类杀虫剂,常用于治疗虱子感染和疥疮。
T13683 Epsilon-momfluorothrin

Momfluorothrin, (Z,1R,3R)-

Others Others
Epsilon-momfluorothrin (Momfluorothrin, (Z,1R,3R)-) 是一种I型合成拟除虫菊酯杀虫剂,通过激活构成型雄烷酮受体(CAR)发挥杀虫特性。在大鼠中,Epsilon-momfluorothrin的给药已观察到可诱导肝细胞肿瘤的发展。
T40623 Chlorempenthrin

Chlorempenthrin is a synthetic pyrethroid insecticide.
T32908 l-trans-Phenothrin

l-trans-Phenothrin, as a synthetic pyrethroid, can kill adult fleas and ticks.
T1200 Phenothrin

苯醚菊酯,Sumithrin

Parasite Microbiology/Virology
Phenothrin (Sumithrin) 是一种合成拟除虫菊酯, 可杀死成虫、蜱和人类的头虱。
T23890 Cismethrin

AI 3-27987,AI-3-27987,AI3-27987

Cismethrin is a pyrethroid insecticide.
T20219 Bioresmethrin

Penick-1390,Bioresmetrina,Penick 1390,Penick1390

Bioresmethrin is a pesticide of synthetic pyrethroid.
T24244 (1R)-cis-Bifenthrin

kappa-Bifenthrine,(R)-Bifenthrin

kappa-Bifenthrin is a pyrethroid insecticide.
T29000 Tralomethrin

EPA Pesticide Chemical Code 121501,SAGA,HAG-107,HAG 107,Scout

Tralomethrin is used as a pyrethroid insecticide. It modifies the gating kinetics of the sodium channels in neurons, increases the length of time the channel remains open after a stimulus, thereby depolarizing the neuron for a longer period of time. This leads to uncontrolled spasms, paralysis, and eventual death.
T24241 Kadethrin

Caswell No. 516AA,ENT 29117,BRN 1605066,AI3-29117,EINECS 261-433-0

Kadethrin is a synthetic pyrethroid. It was used as a pesticide.
T20813 Resmethrin

Resmetrina,Benzofuroline,Isathrine

Resmethrin, a synthetic pyrethroid insecticide, is used against a variety of insects.
T20658 Etofenprox

Etofenprox, a synthetic pyrethroid, has insecticidal efficacy against mosquito larvae & on non-target organisms.
T20787 Cyphenothrin

S-2703,Gokilaht,S2703,S 2703

Cyphenothrin, a synthetic pyrethroid insecticide, is effective against cockroaches that have developed resistance to carbamate and organophosphorous insecticides.
T36836 (4′-Hydroxy)phenoxybenzoic Acid

(4′-Hydroxy)phenoxybenzoic acid is a pyrethroid insecticide metabolite.1,2 1.Akhtar, M.H., Mahadevan, S., and Russell, F.Cleavage of 3-phenoxybenzoic acid by chicken microsomal preparationsJ. Environ. Sci. Health B.28(5)527-543(1993) 2.Maloney, S.E., Maule, A., and Smith, A.R.Microbial transformation of the pyrethroid insecticides: Permethrin, deltamethrin, fastac, fenvalerate, and fluvalinateAppl. Environ. Microbiol.54(11)2874-2876(1988)
T20788 Empenthrin

MA-108,S2852,S 2852,MA108,S-2852,MA 108

Empenthrin, a synthetic pyrethroid used in insecticides, is active against broad spectrum of flying insects including moths and other pests damaging textile.
T25002 Acrinathrin

RU38702,Rufast,RU 38702,RU-38702

Acrinathrin is a pyrethroid used as an insecticide and an acaricide. Although resistance is developing, Acrinathrin is used to control the mite Varroa jacobsoni in beekeeping.
T2214 Flumethrin

Others Others
Flumethrin 是一种拟除虫菊酯类杀虫剂。外用在兽药中,用于防治牛、绵羊、山羊、马和狗身上的寄生虫和蜱,以及治疗蜜蜂群中的寄生虫。
T39255 β-Cyfluthrin

beta-Cyfluthrin,β-Cyfluthrin

β-Cyfluthrin is a type II synthetic pyrethroid compound commonly utilized as an active ingredient in agricultural insecticide products. It exerts its insecticidal properties by acting as a neurotoxicant, primarily impacting the calcium concentration within nervous tissue. This effect is achieved through the inhibition of Ca 2+ ATPase, a crucial component involved in calcium transport.
T35419 τ-Fluvalinate

τ-Fluvalinate is a pyrethroid acaricide.1It induces tail currents in Western honeybee (A. mellifera) voltage-gated sodium channels (AmNav1) expressed inXenopusoocytes (EC50= 60 nM). It also induces tail currents in honeybee parasitic Varroa mite (V. destructor) Nav1 channels (VdNav1) expressed inXenopusoocytes (EC50= 160 nM) with a faster tail current decay than that of AmNav1 channels. Topical application of τ-fluvalinate (2 μl) in combination with coumaphos , atrazine , 2,4-DMPF, chlorpyrifos ...

化合物

Allethrin
Cat.No: T25049
Synonym:
Target: BCL, Caspase
Cyfluthrin
Cat.No: T37688
Synonym:
Target: Reactive Oxygen Species, Sodium Channel
D-Phenothrin
Cat.No: T13633
Synonym: (-)-trans-Phenothrin,右旋苯醚菊酯
Target: Parasite
λ-Cyhalothrin
Cat.No: T27794
Synonym: lambda-Cyhalothrin,Karate,λ-氯氟氰菊酯,Icon
Target: Sodium Channel, Parasite
Transfluthrin
Cat.No: T9751
Synonym:
Target: Others
3-Phenoxybenzaldehyde cyanohydrin
Cat.No: T9434
Synonym: 三苯氧基苯甲醛,2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile
Target: Others
Permethrin
Cat.No: T1332
Synonym: 氯菊酯,Transpermethrin,NRDC-143,Pounce,Ambush
Target: Sodium Channel, Parasite
Epsilon-momfluorothrin
Cat.No: T13683
Synonym: Momfluorothrin, (Z,1R,3R)-
Target: Others
Chlorempenthrin
Cat.No: T40623
Synonym:
Target:
l-trans-Phenothrin
Cat.No: T32908
Synonym:
Target:
Phenothrin
Cat.No: T1200
Synonym: 苯醚菊酯,Sumithrin
Target: Parasite
Cismethrin
Cat.No: T23890
Synonym: AI 3-27987,AI-3-27987,AI3-27987
Target:
Bioresmethrin
Cat.No: T20219
Synonym: Penick-1390,Bioresmetrina,Penick 1390,Penick1390
Target:
(1R)-cis-Bifenthrin
Cat.No: T24244
Synonym: kappa-Bifenthrine,(R)-Bifenthrin
Target:
Tralomethrin
Cat.No: T29000
Synonym: EPA Pesticide Chemical Code 121501,SAGA,HAG-107,HAG 107,Scout
Target:
Kadethrin
Cat.No: T24241
Synonym: Caswell No. 516AA,ENT 29117,BRN 1605066,AI3-29117,EINECS 261-433-0
Target:
Resmethrin
Cat.No: T20813
Synonym: Resmetrina,Benzofuroline,Isathrine
Target:
Etofenprox
Cat.No: T20658
Synonym:
Target:
Cyphenothrin
Cat.No: T20787
Synonym: S-2703,Gokilaht,S2703,S 2703
Target:
(4′-Hydroxy)phenoxybenzoic Acid
Cat.No: T36836
Synonym:
Target:
Empenthrin
Cat.No: T20788
Synonym: MA-108,S2852,S 2852,MA108,S-2852,MA 108
Target:
Acrinathrin
Cat.No: T25002
Synonym: RU38702,Rufast,RU 38702,RU-38702
Target:
Flumethrin
Cat.No: T2214
Synonym:
Target: Others
β-Cyfluthrin
Cat.No: T39255
Synonym: beta-Cyfluthrin,β-Cyfluthrin
Target:
τ-Fluvalinate
Cat.No: T35419
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T20754 Deltamethrin

Butoss,RU-22974,Esbecythrin,溴氰菊酯,K-Othrin,Decamethrin,RU 22974

Others Others
Deltamethrin (RU 22974) 是一种具有神经毒性的拟除虫菊酯杀虫剂,在大鼠中能够产生一系列可逆的运动症状(如包括后肢僵硬、舞蹈性关节炎)。

天然产物

Deltamethrin
Cat.No: T20754
Synonym: Butoss,RU-22974,Esbecythrin,溴氰菊酯,K-Othrin,Decamethrin,RU 22974
Target: Others
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