94
17
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T74969 |
Phospholipid PL1
|
||
Phospholipid PL1 是一种磷脂衍生的纳米颗粒,能够向 T 细胞传递共刺激受体 mRNA (CD137 或 OX40)。Phospholipid PL1 可诱导多种免疫细胞的激活,包括T 细胞和树突状细胞 (DC),以增强抗肿瘤免疫反应。 | |||
T74564 | Phospholipid-PEG-Biotin (MW 2000) | ||
Phospholipid-PEG-Biotin (MW 2000) 是一种PROTAClinker,属于 PEG 类。可用于合成PROTAC 分子。Phospholipid 是一类含有亲水“头”和疏水“尾”的脂类;PEG 是一种低毒性的亲水水溶性聚合物;生物素是一种酶辅因子,可用于标记蛋白质。 | |||
T32781 |
Lipofundin S
Phospholipid - stabilized soybean oil,Intralipid,Intralipid 20,Medialipid,Lipofundin S 10 |
||
Lipofundin S is an emulsion containing soybean oil, glycerol, and soy phosphatides. | |||
T74563 | Phospholipid-PEG-Biotin (MW 1000) | ||
Phospholipid-PEG-Biotin (MW 1000) 和 Phospholipid-PEG-Biotin (MW 3400) 均为磷脂与生物素通过线性聚乙二醇(PEG)连接桥接得到的衍生物。其中,Phospholipid-PEG-Biotin (MW 3400) 能够与亲和抗体发生相互作用,适用于脂质体和细胞表面的修饰,以及胰岛细胞移植领域。 | |||
T74568 | Phospholipid-PEG-Biotin (MW 20000) | ||
Phospholipid-PEG-Biotin (MW 20000) 与 Phospholipid-PEG-Biotin (MW 3400) 均为磷脂和生物素通过线性 PEG 连接剂桥接形成的磷脂聚乙二醇衍生物。其中,Phospholipid-PEG-Biotin (MW 3400) 能与亲和抗体进行相互作用,并可用于修饰脂质体、细胞表面及胰岛细胞移植。 | |||
T83780 |
GPX4 24
Phospholipid Hydroperoxide Glutathione Peroxidase 24,PHGPx 24,Glutathione Peroxidase 4 24 |
||
GPX4 24是(1S,3R)-RSL3的衍生物,具有抑制谷胱甘肽过氧化物酶4(GPX4)的作用。它能够在浓度依赖的方式中与4T1小鼠乳腺癌细胞中的GPX4形成共价结合。在GPX4依赖的HT-1080成纤维细胞中,GPX4 24诱导铁死亡(EC50 = 0.16 µM)。当以200 mg/kg剂量给予小鼠时,它能够增加小鼠肾脏和血浆中丙二醛(MDA)的水平。 | |||
T74566 | Phospholipid-PEG-Biotin (MW 5000) | ||
Phospholipid-PEG-Biotin (MW 5000)为含有磷脂的PEG衍生物,适用于脂质体和细胞表面的修饰,及胰岛细胞移植。Phospholipid具亲水性“头部”与疏水性“尾部”结构,PEG为亲水性低毒聚合物,生物素则作为酶辅因子,用于蛋白质标记。 | |||
T74567 | Phospholipid-PEG-Biotin (MW 10000) | ||
Phospholipid-PEG-Biotin (MW 10000)与Phospholipid-PEG-Biotin (MW 3400)均为磷脂与生物素通过线性PEG连接剂桥接形成的聚乙二醇衍生物。Phospholipid-PEG-Biotin (MW 3400) 能与亲和抗体相互作用,用于脂质体和细胞表面的修饰以及胰岛细胞的移植。 | |||
T74565 | Phospholipid-PEG-Biotin (MW 3400) | ||
Phospholipid-PEG-Biotin (MW 3400) 为一种通过线性PEG链接剂桥接磷脂和生物素的磷脂聚乙二醇衍生物。该化合物能够与亲和抗体进行相互作用,并可用于脂质体及细胞表面的修饰,也适用于胰岛细胞移植。 | |||
TP1444 |
Magainin 2
蛙皮素 2 |
Antibacterial; Antibiotic; Antifungal | Microbiology/Virology |
Magainin 2是从非洲爪蟾皮肤中分离得到的一种抗菌肽。它对许多革兰氏阴性和革兰氏阳性细菌显示出抗生素活性,对原生动物也有活性。它通过优先与细菌膜中丰富的阴离子磷脂相互作用而发挥细胞毒性作用。 | |||
T19080 |
DOPE
1,2-二油酰-SN-甘油-3-磷酰乙醇胺 |
Others | Others |
DOPE (DOPE) 是一种阳离子脂质体的中性辅助脂质 (helper lipid),能够与阳离子磷脂结合,增强裸 siRNA 的转染效率。 | |||
T3034 |
Eprazinone dihydrochloride
Resplen,Mucitux,Eftapan,NSC 317935,盐酸依普拉酮,依普拉酮二盐酸,Eprazinone 2HCl |
Others; Neurokinin receptor | GPCR/G Protein; Neuroscience; Others |
Eprazinone dihydrochloride (NSC 317935) 是一种具有镇咳和粘液溶解作用的粘液溶解剂。它是神经激肽 1 受体的配体,可改善肺功能和动脉血氧分压,可用于慢性支气管炎的研究。 | |||
T74235 |
DHAPC
|
||
DHAPC 是一种对氧化非常敏感的磷脂。 | |||
T35805 |
C16 Sphingomyelin (d18:1/16:0)
Sphingomyelin 16:0,N-Palmitoyl-D-sphingomyelin |
Endogenous Metabolite | Metabolism |
C16 Sphingomyelin (d18:1/16:0) (N-Palmitoyl-D-sphingomyelin) 是磷脂双层膜的磷脂类化合物,可用于研究生物膜的活性。 | |||
TF0112 |
DPPS
12-Dipalmitoyl-sn-glycero-3-PS sodium salt,DPPS-Na |
Others | Others |
DPPS (12-Dipalmitoyl-sn-glycero-3-PS sodium salt) 是一种阴离子二酰基磷脂,是磷脂酰丝氨酸(PS)的一种形式,是一种位于细胞膜内小叶的带负电荷的磷脂。DPPS 被用来制作阳离子囊泡和脂质体。 | |||
T21520 |
DLPC
|
Others | Others |
DLPC 是LRH-1 激动剂的配体,是一种可用于生物学研究的磷脂。 | |||
T9994 |
WAY-620521
|
Others | Others |
WAY-620521是一种用于细胞的高通量测定小分子。 | |||
T20642 |
Laurdan
6-十二酰基-N,N-二甲基-2-萘胺,6-Dodecanoyl-2-dimethylaminonaphthalene |
Others | Others |
Laurdan (6-Dodecanoyl-2-dimethylaminonaphthalene) 是膜透性荧光探针。它的广义极化 (GP) 定量可用于磷脂相的鉴定,对与之结合的细胞膜磷脂相具有光谱敏感性。 | |||
T74305 |
14:0 PEG2000 PE
DMPE-PEG2000 |
Others | Others |
14: 0 PEG2000 PE (DMPE-PEG2000) 是一种聚乙二醇 (PEG)-磷脂偶联物,可在制备囊泡制剂时阻止囊泡聚集,可用于制备纳米结构脂质载体。 | |||
T4949 |
1,2-Didecanoyl-sn-glycero-3-phosphocholi
1,2-Didecanoyl Phosphatidylcholine,1,2-Didecanoyl PC,L-A-癸酰磷脂酰胆碱 |
Others | Others |
1,2-Didecanoyl-sn-glycero-3-phosphocholi (1,2-Didecanoyl PC) 是一种合成的、疏水性较低的磷脂,已被发现可用于增强肽类药物和激素(如胰岛素)的吸收。 | |||
T29099L |
VB 201
CI-201 |
TLR | Immunology/Inflammation |
VB 201 是一种氧化磷脂小分子,具有抗炎活性,可抑制 CD14 和 Toll 样受体 2 依赖性先天细胞活化并限制动脉粥样硬化,可用于研究动脉粥样硬化。 | |||
T38404 |
MJ33 lithium salt
|
ROS | Immunology/Inflammation |
MJ33 lithium salt 是 NADPH 氧化酶 2 型介导的 ROS 生成抑制剂,是一种氟化磷脂类似物,可抑制过氧化物还蛋白 6 (Prdx6) 的磷脂酶 A2 (PLA2) 活性,可用于研究急性肺损伤。 | |||
TP1902L1 |
G-Protein antagonist peptide acetate
|
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
G-Protein antagonist peptide acetate 是一种 substance P 相关肽,可抑制 G 蛋白与其受体的结合。G-Protein antagonist peptide acetate 竞争性和可逆性地抑制毒蕈碱型乙酰胆碱受体 M2 (M2 muscarinic receptor) 对 Gi 或 Go 的激活,并通过 β-肾上腺素受体抑制 Gs 的激活。 | |||
T77277 |
DSPE-alkyne
|
||
DSPE-alkyne 是一种磷脂。 | |||
T21141 |
Decylene glycol
Decane-1,2-diol,AI3-16595,1,2-Decanediol |
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Decylene glycol is used as an antimicrobial agent in cosmetics. It also suppresses the fluidity of the hydrophobic and hydrophilic groups in the phospholipid membrane of liposomes. | |||
T27094 |
CT-2584
CT2584 |
||
CT-2584 is an angiogenesis inhibitor and lysophosphatidic acid acyltransferase inhibitor. CT-2584 inhibits phospholipid signaling. By inhibiting CTP:choline-phosphate cytidylyltransferase (CT), CT-2584 caused de novo phospholipid biosynthesis via PA to be | |||
T74316 |
12:0 EPC chloride
|
||
12:0 EPC chloride 为阳离子磷脂。12:0 EPC chloride 可用于活性分子输送。 | |||
T70298 |
CT 2576
|
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CT 2576 is an inhibitor of phospholipid signaling, suppresses constitutive and induced expression of human immunodeficiency virus | |||
T33094 | Lysylphosphatidylglycerol | ||
Lysylphosphatidylglycerol is glycerol with two fatty acids plus a lysine-glycerol-phosphate, a major membrane phospholipid of Staphylococcus and the lysine positive charge repels DEFENSINS. | |||
T68698 | VPC 23153 | ||
VPC 23153 is a sphingosine 1-phosphate 4 receptor agonist. This hygroscopic phospholipid causes contraction of pulmonary artries in rats. | |||
T77281 |
DSPE-Thiol
|
||
SPE-Thiol是具有末端硫醇基团的磷脂,其硫醇头部能够选择性与马来酰亚胺进行反应。此外,DSPE-Thiol亦可应用于磷脂二聚体的制备中。 | |||
T29809 |
AL-1
AL 1,AL1 |
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AL-1 is a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR containing ephrin found in developing tectum. It can mediate the bundling of cortical axons and repel the axonal growth of retinal ganglia axons. It exists in a variety of adult tissues of BRAIN; HEART; | |||
T36763 |
PAF C-18
|
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PAF C-18 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the remodeling" and 'de novo' pathways. It is less potent than PAF C-16 in the induction of platelet aggregation | |||
T35959 |
PGPC
1-Palmitoyl-2-glutaryl phosphatidylcholine |
Others | Others |
PGPC (1-Palmitoyl-2-glutaryl phosphatidylcholine) 是一种氧化磷脂,以浓度依赖性方式激活过氧化物酶体增殖物激活受体。 | |||
T74302 | DSPE-PEG-PDP | ||
DSPE-PEG-PDP 是一种磷脂 PEG 偶联物,可用于药物递送应用。 | |||
T37623 |
1,2-Dierucoyl-sn-glycero-3-PC
|
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1,2-Dierucoyl-sn-glycero-3-PC is a phospholipid containing erucic acid at the sn-1 and sn-2 positions. It has been used in the study of lipid membranes and to determine the effect of long-chain phospholipids on the secondary structure of human islet amyloid polypeptide (hIAPP). | |||
T37268 |
PAF C-16 Carboxylic Acid
|
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PAF C-16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the remodeling" and 'de novo' pathways. It is a potent mediator of neutrophil migration and the production of reactive oxygen species and IL-6. Pathological processes involving PAF include necrotizing enterocolitis | |||
T77286 |
DSPE-SPDP
|
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DSPE-SPDP,一种磷脂分子,能够在水中自行定向并形成脂质双层,适用于多种生化研究。 | |||
T77287 | DSPE-Rhodamine | ||
DSPE-Rhodamine,一种标记有罗丹明 B (Rhodamine B) 的磷脂DSPE,用于制备荧光标记的脂质体。 | |||
T74031 |
Cardiolipin (Heart, Bovine) (sodium)
|
||
Cardiolipin (Heart, Bovine) sodium,一种线粒体专有磷脂,展现出在神经系统疾病研究中的应用潜力。 | |||
T74228 | DSPE-mPEG-2000 | ||
DSPE-mPEG-2000 是基于 PEG 的磷脂。DSPE-mPEG-2000 可用于合成传递肿瘤活性分子的脂质体。 | |||
T74303 | DSPE-PEG-Carboxylic Acid | ||
DSPE-PEG-Carboxylic Acid,一种磷脂PEG偶联物,广泛应用于靶向活性分子和基因递送。 | |||
TP1811 |
LAH4
|
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The a-helix of the amphipathic peptide antibiotic LAH4 (KKALLALALHHLAHLALHLALALKKA-NH2) strongly interacts with phospholipid membranes, demonstrating in vitro transfection efficiencies comparable to those of commercially available reagents. | |||
T74870 | TMX-201 | ||
TMX-201,一种TLR7配体-磷脂共轭物,表现出显著的免疫刺激活性,适用于乳腺癌与黑色素瘤的研究。 | |||
T83476 |
1,2-Diheptadecanoyl-sn-glycero-3-phosphorylcholine
DHPC |
||
1,2-Diheptadecanoyl-sn-glycero-3-phosphorylcholine (DHPC) 是生物活性磷脂化合物,属于磷脂酰胆碱 (PC) 的衍生物。 | |||
T73733 |
(Rac)-1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium
|
||
(Rac)-1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (sodium) 为阴离子磷脂, 主要应用于药物递送及脂质体合成。 | |||
T38967 |
DSPE-PEG(2000)
|
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MPEG-2000-DSPE sodium is a phospholipid PEG conjugate with hydrophilicity and hydrophobicity. It is utilized in liposome synthesis to enhance the hydrophilicity of liposomes, thereby prolonging their circulation in the bloodstream. This compound is commonly employed for the investigation of anticancer and antimalarial agents. | |||
T36143 |
10-Pyrene-PC
|
||
10-Pyrene-PC is a substrate for all PLA2s with the exception of cPLA2 and PAF-AH. Upon phospholipid hydrolysis, 10-pyrenyldecanoic acid is produced from 10-pyrene-PC. The monomeric 10-pyrenyldecanoic acid exhibits fluorescence (excitation 345 nm, emission 395 nm), allowing quantitation of phospholipase activity. | |||
T37485 |
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC
|
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1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC by 15-lipoxygenase (15-LO). | |||
T74875 |
1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate
|
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1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate 是脂质化合物,主要用于提高磷脂囊泡包封蛋白质的效率。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9525 |
1,2-Dimyristoyl-sn-glycero-3-phosphocholine
DMPC,1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOL,二肉豆蔻酰磷脂酰胆碱(DMPC) |
Others | Others |
1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) 是一种用于脂质体和脂质双层的合成磷脂。它可用于脂质单层和双层的研究。 | |||
T19085 |
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC
POPC,2-油酰-1-棕榈锡甘油-3-磷酸胆碱,1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine,Palmitoyloleoylphosphatidylcholine |
Others | Others |
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (Palmitoyloleoylphosphatidylcholine) 是生物膜的主要成分,是一种磷脂。它用于脂质体的制备以及脂质双层的特性的研究。 | |||
T38141 |
Glycerophospholipids, cephalins
Phosphatidylethanolamines (egg) |
||
Glycerophospholipids, cephalins (Phosphatidylethanolamines (egg)) 是一种从鸡蛋中分离出来的磷脂酰乙醇胺的混合物,在 sn-1和 sn-2位置有各种脂肪酰基。Glycerophospholipids, cephalins 完全水解可得到1mol 的甘油、磷酸、乙醇胺和2mol 的脂肪酸。Phosphatidylethanolamines 在膜融合和细胞分裂过程中收缩环的拆卸中起作用,可调节膜的弯曲度。Phosphatidylethanolamines 能够在没有任何蛋白质或核酸的帮助下传播传染性朊病毒。Phosphatidylethanolamines 在细菌膜中的主要作用之一是分散由阴离子膜磷脂引起的负电荷。 | |||
T9503 |
PHYTOSPHINGOSINE
|
Apoptosis | Apoptosis |
Phytosphingosine 是具有抗癌作用的一种磷脂。在癌细胞中,它通过 caspase 8 的激活和 Bax 转位诱导细胞凋亡。 | |||
T8011 |
1,2-dioleoyl-sn-glycero-3-phosphocholine
二油酰磷脂酰胆碱,DOPC |
Others | Others |
1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) 是磷脂的一种,在胶束,脂质体和其他类型的人工膜的生成中通常单独使用或与其他组分一起使用。 | |||
T4881 |
Phosphorylethanolamine
O-Phosphorylethanolamine,乙醇胺磷酸酯 |
Others; Endogenous Metabolite | Metabolism; Others |
Phosphorylethanolamine (O-Phosphorylethanolamine) 是磷脂代谢的一种磷酸单酯代谢物。Phosphorylethanolamine 是磷脂合成的前体,也是磷脂分解的产物。与其他器官相比,大脑中磷酸单酯的含量要高得多。在大脑发育过程中,磷单酯通常在神经增生期间升高。这也与大脑发育过程中正常的程序性细胞死亡和突触修剪的发生相吻合。这些发现与磷酸单酯在膜生物合成中的作用是一致的。Phosphorylethanolamine 与抑制性神经递质GABA和GABAB受体部分激动剂 3-氨基丙基膦酸具有很强的结构相似性。Phosphorylethanolamine 是一种磷单酯,在阿尔茨海默病患者的大脑中减少。 | |||
TN7244 |
Egg PG
Phosphatidylglycerols(egg) |
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Egg PG(Phosphatidylglycerols(egg)) 是一种食物和生物组织的主要磷脂酰甘油之一,常存在于细菌和动物细胞的膜中,可作为 sPMCA,反应中的阴离子磷脂底物。 | |||
T21437 |
DSPS
Phosphatidylserine(36:0),磷脂酰丝氨酸,Dioctadecanoylphosphatidylserine,Distearoyl phosphatidylserine |
Others | Others |
DSPS (Dioctadecanoylphosphatidylserine) 是一种甘油磷脂,是重要的磷脂膜成分,在细胞周期信号传导中起关键作用。DSPS 可以调节细胞活性,介导细胞凋亡。DSPS 被广泛用作营养补充剂。 | |||
T5238 |
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
1,2-Dipalmitoyl-sn-glycero-3-PE,L-磷脂酰乙醇胺,1,2-Dipalmitoyl-sn-glycerol-3-Phosphoethanolamine,1,2-DPPE |
Others; Endogenous Metabolite | Metabolism; Others |
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE) 是内源性代谢产物的一种。 | |||
T4869 |
D-Allose
阿洛糖,β-D-Allopyranose,D-(+)-ALLOSE |
Others; Endogenous Metabolite | Metabolism; Others |
D-Allose (β-D-Allopyranose) 是内源性代谢产物的一种。 | |||
T4809 |
Pyrimidine
嘧啶,Metadiazine |
Others; Endogenous Metabolite | Metabolism; Others |
Pyrimidine (Metadiazine) 是内源性代谢产物的一种。 | |||
TN4406 |
Lamiide
|
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Lamiide has anti-inflammatory activity in carrageenin-induced paw edema test. It shows lipid peroxidation inhibition on rat-brain phospholipid peroxidation. | |||
T73812 |
Phosphatidylinositol 4,5-bisphosphate
|
||
Phosphatidylinositol 4,5-bisphosphate(L-alpha-Phosphatidylinositol-4,5-bisphosphate)为细胞膜磷脂成分,主要作为磷脂酶C(PLC)与磷酸肌醇3-激酶(PI3K)的底物,充当重要信使。 | |||
T73602 |
Phosphorylcholine
Phosphocholine |
Endogenous Metabolite | Metabolism |
Phosphorylcholine 广泛存在于生物界,是存在于真核生物膜中的磷脂,也存在于与真核生物相关联的共生菌或致病菌中。Phosphorylcholine 具有免疫调节特性,可用于研究动脉粥样硬化。 | |||
T37219 |
N-Palmitoyl Glycine
|
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The acyl amides are a family of endogenous lipids that act as potent modulators of pain and inflammation. The best characterized members of this family are the arachidonoyl amides, which includes N-arachidonoyl ethanolamide (AEA; anandamide). N-palmitoyl glycine (PalGly) contains an 18-carbon saturated fatty acid that is amide-linked to glycine and is structurally similar to the phospholipid-derived N-acyl ethanolamines. Endogenously produced in rat skin and spinal cord, PalGly is present in 100... | |||
T35577 |
Phosphatidylserines (bovine)
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Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on the inner leaflet of the cell membrane. It is biosynthesized from phosphatidylcholine or phosphatidylethanolamine by phosphatidyl synthase 1 (PSS1) or PSS2, respectively, in the endoplasmic reticulum and can be reversibly converted back by the same enzymes. It can also be irreversi... | |||
T37770 |
Taurohyodeoxycholic acid
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Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid .1THDCA decreases the size and weight of human gallstonesin vitro. It increases bile flow, biliary cholesterol secretion, and biliary lipid secretion in rats.2Co-administration of THDCA with taurochenodeoxycholic acid prevents TCDCA-induced hepatotoxicity, increasing bile flow as well as biliary acid and phospholipid secretion in rats.3THDCA also reduces myeloperoxidase activity, expressi... |