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Search Results for " nitroimidazole "

33

抑制剂 & 化合物

3

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T0638	2-Methyl-4-nitroimidazole	Others	Others
	2-Methyl-4-nitroimidazole（2-MNI）是一种杂环化合物，具有抗菌、抗炎和抗肿瘤活性。2-MNI 已被用于多种领域，包括生物化学、药理学和生物技术。
T15202	EF-5 2-Nitroimidazole,EF5	Others	Others
	EF-5 (2-Nitroimidazole) 是一种能够用于鉴定细胞缺氧的缺氧标记试剂。
T0874	Dimetridazole 1, 2-Dimethyl-5-nitroimidazole,1,2-Dimethyl-5-nitroimidazole,二甲硝咪唑	Antibiotic; Parasite	Microbiology/Virology
	Dimetridazole (1, 2-Dimethyl-5-nitroimidazole) 是一种对抗原生动物感染的硝基咪唑类药物。
T65596	1-Methyl-4-nitroimidazole
	1-Methyl-4-nitroimidazole 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65596，CAS号为 3034-41-1。
T37514	Hydroxy Dimetridazole	Drug Metabolite	Metabolism
	Hydroxy Dimetridazole 是Dimetridazol 的羟基化代谢产物。Dimetridazol 是一种硝基咪唑类药物，可用于对抗原生动物感染。
T67500	5-Chloro-1-methyl-4-nitroimidazole
	5-Chloro-1-methyl-4-nitroimidazole 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67500，CAS号为 4897-25-0。
T1647	Ronidazole 洛硝哒唑,Ronidazol,罗硝唑,Ridzol	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Ronidazole (Ronidazol) 是一种口服有效的抗原虫和抗菌试剂。它在猫模型中对胎儿三毛滴虫有效，还可研究组织口癣和猪痢疾。
T2112	Fexinidazole 非昔硝唑,HOE 239	Others; Parasite	Microbiology/Virology; Others
	Fexinidazole (HOE 239) 是具有口服活性的硝基咪唑抗锥虫药物。它显示出对布鲁氏杆菌亚种和菌株的杀锥虫活性，IC50值为 0.7-3.3 μM (0.2-0.9 μg/ml)。它具有用于因感染布鲁氏菌引起的人类昏睡病的潜力。
T68110	Moxnidazole
	Moxnidazole 是一种5-硝基咪唑，在微生物试验和果蝇中具有诱变性，诱导小鼠体细胞的遗传改变。
T3615	Evofosfamide 艾伏磷酰胺,TH-302	Apoptosis; Others	Apoptosis; Others
	Evofosfamide (TH-302) 是一种缺氧激活前药，在缺氧 (N2) 和常氧 (21% O2) 环境下，IC50分别为 10 μM 和 1000 μM。
T2046	Nimorazole Nimorazol,Nitrimidazine,尼莫唑,K-1900,Naxogin,尼莫拉唑	Others; Antibiotic; Parasite	Microbiology/Virology; Others
	Nimorazole (Nimorazol) 是一种 2-硝基咪唑，是一种低氧细胞辐射敏化剂。它具有抗感染，抗滴虫等原生动物的作用。它有头颈癌的研究潜力。
T34705	SR4554 SR 4554
	SR4554 is a fluorine-containing 2-nitroimidazole, designed as a hypoxia marker detectable with 19F magnetic resonance spectroscopy (MRS). SR-4554 has plasma pharmacokinetic and toxicity profiles suitable for use as a hypoxia probe. It can be detected in t
T6096	Pretomanid (S)-PA 824,PA-824	Antibacterial; Antibiotic	Microbiology/Virology
	Pretomanid ((S)-PA 824) 是一种抗生素，可研究肺部多重耐药性结核病。它对结核病(MTB) 具有亚微摩尔作用活性。它对 MTB 泛敏感和抗 Rifampin 的临床分离株的 MIC 值为 0.015 至 0.25 μg/mL。
T0195	Secnidazole RP-14539,PM-185184,塞克硝唑	Antibiotic; Parasite	Microbiology/Virology
	Secnidazole (PM-185184) 是一种具有口服活性唑类抗生素，半衰期比甲硝唑更长。它有潜力研究细菌性阴道病。
T0893	Tinidazole 替硝唑,CP12574	Antibacterial; Antibiotic	Microbiology/Virology
	Tinidazole (CP12574) 是一种对厌氧菌和原生动物具有选择性抗菌活性的 5-硝基咪唑，是一种具有口服活性的抗菌剂。
T26532	Abunidazole
	Abunidazole is a nitroimidazole antifungal drug.
T37524	Ternidazole hydrochloride
	Ternidazole hydrochloride, a hydroxymetabolite derived from nitroimidazole, exhibits antiprotozoic properties [1][2].
T34422	RSU 1131 RSU1131,RSU-1131
	RSU 1131 is a nitroimidazole-aziridine.
T26990	CGI-17341 CGI17341
	CGI-17341 is an orally active representative of the 5-nitroimidazole series of antimicrobial agents. CGI 17341 inhibits the drug-susceptible and multi-drug-resistant strains of Mycobacterium tuberculosis at concentrations ranging from 0.1 to 0.3 microgram
T40573	Hydroxymetronidazole Hydroxymetronidazole,Metronidazole-OH
	Hydroxymetronidazole (Metronidazole-OH) is a nitroimidazole compound that functions as a metabolite of Metronidazole. It is commonly employed in poultry research to investigate bacterial and protozoal diseases, as well as in the study of swine dysentery and genital trichomoniasis in cattle.
T60363	Nitrefazole
	Nitrefazole 是一种4-nitroimidazole 衍生物，对醛脱氢酶(ALDH)具有强烈而持久的抑制作用，醛脱氢酶是一种参与酒精代谢的酶。
T26130	RS 029 RS029,RS-029
	RS 029 is a nitroimidazole that has been exhibited to significantly inhibit (Na+K+) ATP-ase activity.
T34350	Ro 15-0216 Ro-15-0216,Ro15-0216
	RO 15-0216, a nitroimidazole compound, is active against human and animal pathogenic trypanosoma africanum in vitro.
T28011	Megazol CL 64855,CL-64855,CL64855
	Megazol is a nitroimidazole based drug that cures some protozoan infections. A study of nitroimidazoles found the drug extremely effective against T. cruzi and T. brucei which cause Chagas disease and African sleeping sickness, respectively.
T11013	Dextrorotation nimorazole phosphate ester	Others	Others
	Dextrorotation nimorazole phosphate ester is an anti-anaerobic and anti-parasitic agent. D-morpholine ornidazole organic phosphate is a newly developed, highly efficient, well-tolerated fourth-generation nitroimidazole derivative. Objective: Antibacterial
T24277	Hydroxy ipronidazole L-12407,Ipronidazole-OH,L12407,L 12407
	L 12407 is an antiprotozoal drug of the nitroimidazole class. It is used for the treatment of histomoniasis in turkeys and for swine dysentery.
T33698	NLA 1 NLA1,NLA-1
	NLA 1是一种生物还原性化合物，一种嵌入靶向DNA 的2-硝基咪唑放射增敏剂。NLA-1以类似于9-aminoacridine 的亲和力可逆地结合DNA，并且作为细胞毒素的效力大约是MISO 的1000倍。
T69714	Etanidazole
	Etanidazole (SR-2508) is a 2-nitroimidazole drug with radiosensitizing properties. Etanidazole depletes glutathione and inhibits glutathione transferase, thereby enhancing the cytotoxicity of ionizing radiation. This agent may also be useful as an imaging agent for identifying hypoxic, drug-resistant regions of primary tumors or metastases. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
T70813	DTP348
	DTP348 is an oral dual CAIX inhibitor/ radiosensitizer. DTP 348 is an oral dual drug with two mechanisms of action: (1). carbonic anhydrase IX inhibitor which acidifies the intracellular pH through the sulfamide components; (2). radio sensitizer of hypoxic cells through its 5-nitroimidazole moiety.
T9233	Metronidazole acetic acid	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Metronidazole acetic acid 是 Metronidazole 的代谢产物，在细菌中具有诱变活性。Metronidazole 是硝基咪唑类抗生素，杀螨剂和抗原生动物剂。
T26049	RB 6145 RB6145,RB-6145
	RB 6145是一种双功能硝基咪唑，低氧细胞放射增敏剂RSU 1069的前药，它的毒性较RSU 1069降低。它具有缺氧细胞优先细胞毒性和抗肿瘤治疗活性。
T75285	Metronidazole hydrochloride
	Metronidazole hydrochloride (SC 326421) 是一种有口服活性的硝基咪唑抗生素，适用于厌氧微生物感染的研究。该化合物能穿越血脑屏障，长期服用可能引发炎症和骨骼肌收缩问题。
T40605	N-(2-Hydroxyethyl)oxamic acid
	N-(2-hydroxyethyl)-oxamic acid, a compound derived from the reduction of Metronidazole, can result from either chemical processes or through interaction with intestinal bacteria. Metronidazole itself is a nitroimidazole antibiotic with a broad range of efficacy against protozoans, as well as both Gram-negative and Gram-positive anaerobic bacteria.

化合物

2-Methyl-4-nitroimidazole

Cat.No: T0638

Target: Others

Cat.No: T15202

Synonym: 2-Nitroimidazole,EF5

Target: Others

Cat.No: T0874

Synonym: 1, 2-Dimethyl-5-nitroimidazole,1,2-Dimethyl-5-nitroimidazole,二甲硝咪唑

Target: Antibiotic, Parasite

1-Methyl-4-nitroimidazole

Cat.No: T65596

Hydroxy Dimetridazole

Cat.No: T37514

Target: Drug Metabolite

5-Chloro-1-methyl-4-nitroimidazole

Cat.No: T67500

Cat.No: T1647

Synonym: 洛硝哒唑,Ronidazol,罗硝唑,Ridzol

Target: Antibacterial, Antibiotic, Parasite

Cat.No: T2112

Synonym: 非昔硝唑,HOE 239

Target: Others, Parasite

Cat.No: T68110

Cat.No: T3615

Synonym: 艾伏磷酰胺,TH-302

Target: Apoptosis, Others

Cat.No: T2046

Synonym: Nimorazol,Nitrimidazine,尼莫唑,K-1900,Naxogin,尼莫拉唑

Target: Others, Antibiotic, Parasite

Cat.No: T34705

Synonym: SR 4554

Cat.No: T6096

Synonym: (S)-PA 824,PA-824

Target: Antibacterial, Antibiotic

Cat.No: T0195

Synonym: RP-14539,PM-185184,塞克硝唑

Target: Antibiotic, Parasite

Cat.No: T0893

Synonym: 替硝唑,CP12574

Target: Antibacterial, Antibiotic

Cat.No: T26532

Ternidazole hydrochloride

Cat.No: T37524

Cat.No: T34422

Synonym: RSU1131,RSU-1131

Cat.No: T26990

Synonym: CGI17341

Hydroxymetronidazole

Cat.No: T40573

Synonym: Hydroxymetronidazole,Metronidazole-OH

Cat.No: T60363

Cat.No: T26130

Synonym: RS029,RS-029

Cat.No: T34350

Synonym: Ro-15-0216,Ro15-0216

Cat.No: T28011

Synonym: CL 64855,CL-64855,CL64855

Dextrorotation nimorazole phosphate ester

Cat.No: T11013

Target: Others

Hydroxy ipronidazole

Cat.No: T24277

Synonym: L-12407,Ipronidazole-OH,L12407,L 12407

Cat.No: T33698

Synonym: NLA1,NLA-1

Cat.No: T69714

Cat.No: T70813

Metronidazole acetic acid

Cat.No: T9233

Target: Antibacterial, Antibiotic, Parasite

Cat.No: T26049

Synonym: RB6145,RB-6145

Metronidazole hydrochloride

Cat.No: T75285

N-(2-Hydroxyethyl)oxamic acid

Cat.No: T40605

Cat. No.	Product Name	Target	Signaling Pathways
T6402	Azomycin 2-Nitroimidazole,2-硝基咪唑,Ro 05-9129,Amicin	Antibacterial; Antibiotic	Microbiology/Virology
	Azomycin (Ro 05-9129) 是一种可抑制有氧革兰氏阳性菌和革兰氏阴性菌的生长的抗生素。
T1079	Metronidazole Flagyl,Metronidazol,甲硝唑,Anagiardil	Apoptosis; NADPH; Hydrogenase; Antibacterial; Antibiotic; Parasite; Antifection	Apoptosis; Metabolism; Microbiology/Virology
	Metronidazole (Metronidazol) 是一种合成的硝基咪唑衍生物，具有抗原生动物和抗菌活性。
T1556	Ornidazole Tiberal,Ornidazolum,NSC 95075,Ro 7-0207,奥硝唑	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Ornidazole (Tiberal) 是一种5-硝基咪唑衍生物，能抗原生动物和厌氧菌。

天然产物

Cat.No: T6402

Synonym: 2-Nitroimidazole,2-硝基咪唑,Ro 05-9129,Amicin

Target: Antibacterial, Antibiotic

Cat.No: T1079

Synonym: Flagyl,Metronidazol,甲硝唑,Anagiardil

Target: Apoptosis, NADPH, Hydrogenase, Antibacterial, Antibiotic, Parasite, Antifection

Cat.No: T1556

Synonym: Tiberal,Ornidazolum,NSC 95075,Ro 7-0207,奥硝唑

Target: Antibacterial, Antibiotic, Parasite

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