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12

抑制剂 & 化合物

3

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T16531	Picaridin 埃卡瑞丁,Lcaridin	Parasite	Microbiology/Virology
	Picaridin (Lcaridin) 是一种广谱节肢动物驱避剂，作用于蚊子和蜱的嗅觉感应，与其气味受体蛋白相互作用。
T13633	D-Phenothrin (-)-trans-Phenothrin,右旋苯醚菊酯	Parasite	Microbiology/Virology
	D-Phenothrin ((-)-trans-Phenothrin) 是一种口服有效的 II 型合成拟除虫菊酯，广泛用于杀死昆虫，蚊子和人类虱子。它还用于兽医，保护农作物和控制动物上的害虫。
T19803	Fenoxycarb 苯氧威,Ethyl 2-(4-phenoxyphenoxy)ethylcarbamate,Pyctyl,Insegar	Others	Others
	Fenoxycarb (Insegar) 是一种灭蚊剂。
T0997	Temephos 双硫磷,Temefos	AChR; Parasite	Microbiology/Virology; Neuroscience
	Temephos (Temefos) 是一种胆碱酯酶抑制剂，是一种有机硫代磷酸盐杀虫剂，用于治疗被携带疾病的昆虫侵染的水。
T0976	Propoxur 残杀威,Aprocarb,Propoxure,Baygon	AChR; Antifungal	Microbiology/Virology; Neuroscience
	Propoxur (Propoxure) 是一种氨基甲酸酯类杀虫剂，用于控制蟑螂、苍蝇、蚊子以及草坪和草坪昆虫。
T26051	RE 11775 RE-11775,RE11775
	RE 11775 is used as a carbamate insecticide with promising activity against organophosphorus-resistant mosquitoes.
T40613	Butopyronoxyl
	Butopyronoxyl is an insect repellent that can be mainly used to repel mosquitoes.
T30470	Bisazir AI3-61585
	Bisazir effects male sterility in Anopheles albimanus mosquitoes.
T20785	Terallethrin M-108,M 108,M108,Knockthrin
	Terallethrin, a pesticide, controls flying insects including houseflies, mosquitoes, and wasps.
T20818	Propetamphos Deadmag,Safrotin S 200
	Propetamphos, an organophosphate pesticide, can effectively control cockroaches, flies, mosquitoes, and other pests. It is also effective for cattle lice.
T73466	Pulixin
	Pulixin 阻碍了 FREP1 与恶性疟原虫感染细胞的裂解物的结合，防止传播至蚊子，其中EC50值为11 µM。同时，Pulixin 抑制无性期恶性疟原虫的增殖，EC50值达47 nM。
T36584	HNMPA-(AM)3	Tyrosine Kinases	Tyrosine Kinase/Adaptors
	HNMPA-(AM)3 抑制 ERK 磷酸化的激活以及促促胸腺激素 (PTTH) 刺激蜕皮类固醇产生。此外，HNMPA-(AM)3 对蜕皮类固醇产生 (IC50=14.2 μM) 和胰岛素受体活性 (IC50=14.2 μM 和 200 μM，在蚊子和哺乳动物中分别) 具有抑制作用。

化合物

Cat.No: T16531

Synonym: 埃卡瑞丁,Lcaridin

Target: Parasite

Cat.No: T13633

Synonym: (-)-trans-Phenothrin,右旋苯醚菊酯

Target: Parasite

Cat.No: T19803

Synonym: 苯氧威,Ethyl 2-(4-phenoxyphenoxy)ethylcarbamate,Pyctyl,Insegar

Target: Others

Cat.No: T0997

Synonym: 双硫磷,Temefos

Target: AChR, Parasite

Cat.No: T0976

Synonym: 残杀威,Aprocarb,Propoxure,Baygon

Target: AChR, Antifungal

Cat.No: T26051

Synonym: RE-11775,RE11775

Cat.No: T40613

Cat.No: T30470

Synonym: AI3-61585

Cat.No: T20785

Synonym: M-108,M 108,M108,Knockthrin

Cat.No: T20818

Synonym: Deadmag,Safrotin S 200

Cat.No: T73466

Cat.No: T36584

Target: Tyrosine Kinases

Cat. No.	Product Name	Target	Signaling Pathways
TN4694	Odoratone	Others	Others
	Odoratone shows insecticidal activities, it shows mortality on fourth instar larvae of mosquitoes (Anopheles stephensi) with LC(50) values of 154 ppm. Odoratone exhibits strong antifeedant activity against Pieris brassicae.
T75450	P-orlandin
	P-orlandin，一种真菌代谢产物，具有阻止FREP1与其配子体或[卵动细胞]结合的功能。该化合物能有效抑制蚊子体内的恶性疟原虫感染。
TN1638	Evodol	Others	Others
	Evodol may as an anti-inflammatory agent or lead compound, it shows inhibitory activity on nitric oxide (NO) production in lipopolysaccharide -activated RAW264.7 macrophages. Evodol and limonin possess larvicidal activity against the Asian tiger mosquitoe

天然产物

Cat.No: TN4694

Target: Others

Cat.No: T75450

Cat.No: TN1638

Target: Others

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