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Search Results for " microsomal triglyceride transfer protein "

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Cat. No.	Product Name	Target	Signaling Pathways
T27719	KD-026 SLx 4090,SLx4090,KD026,SLx-4090	CETP	Metabolism
	KD-026 (SLx 4090) 是具有口服活性的、肠细胞特异性的微粒体甘油三酯转移蛋白 (MTP)抑制剂，IC50为 8.0 nM。KD-026 (SLx 4090) 在糖尿病2型中有研究的价值。
T2545	Lomitapide Mesylate 甲磺酸洛美他派,BMS-201038 mesylate,AEGR-733 mesylate	CETP	Metabolism
	Lomitapide Mesylate (BMS-201038 mesylate) 是一种高效MTP 蛋白抑制剂，其体外IC50值为8 nM。
T30506	BMS-212122 UNII-0Z473OO6GB,BMS212122,BMS 212122	CETP	Metabolism
	BMS-212122 (UNII-0Z473OO6GB) 是一种有效的微粒体甘油三酯转移蛋白(MTP )抑制剂，在动物实验中显示出降血脂作用。BMS-212122 显著减少动脉粥样硬化斑块中的脂质含量和单核细胞衍生(CD68+)细胞。
T15006	Dirlotapide CP742033,Slentrol	Others; CETP	Metabolism; Others
	Dirlotapide (CP742033) 是一种肠道选择性微粒体甘油三酯转移蛋白(MTP)抑制剂。它可以减轻糖尿病狗的体重。Dirlotapide 以剂量依赖性方式减少食物摄入量，可能是通过增加肽YY 释放到循环中。
T31992	Granotapide	CETP	Metabolism
	Granotapide 是一种微粒体甘油三酯转移蛋白（MTP）抑制剂，治疗和而预防动脉硬化，冠状动脉疾病，代谢综合征，肥胖，糖尿病，糖尿病前期和高血压。
T6267	Lomitapide AEGR-733,洛美他派,BMS-201038	CETP	Metabolism
	Lomitapide (AEGR-733) 是一种高效的微粒体甘油三酯转移蛋白(MTP)抑制剂，体内试验的IC50值为8 nM。
T10504	Implitapide Racemate	Others	Others
	Implitapide Racemate is the racemate of Implitapide. Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).
T24223	JTT 130 JTT-130,JTT130
	JTT 130 is an agent of hypolipidemic. It inhibits microsomal triglyceride transfer protein.
T13418	CP-319340(free base)	Others	Others
	CP-319340 free base is a inhibitor of microsomal triglyceride transfer protein (MTP) .
T15570	Implitapide 英普他派,AEGR 427	CETP	Metabolism
	Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).
T16158	PF-02575799	Adenosine Receptor	GPCR/G Protein; Neuroscience
	PF-02575799 is an inhibitor of microsomal triglyceride transfer protein (MTP) (IC50: 0.77±0.29 nM).
T35005	Usistapide R-256918,JNJ-16269110,JNJ16269110,R256918,JNJ 16269110,R 256918
	UsISpide(JNJ-16269110 R256918) is an inhibitor of microsomal triglyceride transfer protein (MTTP) under development for the treatment of obesity and type 2 diabetes.
T38666	CP-346086 dihydrate
	CP-346086 dihydrate is a potent and orally active inhibitor of microsomal triglyceride transfer protein (MTP), exhibiting an IC50 value of 2.0 nM for both human and rodent MTP. This compound effectively lowers plasma cholesterol and triglyceride levels in vivo.
T68375	KD026-metabolite
	KD026-metabolite, is a metabolite of KD-026. KD026, also known as SLx-4090, is a microsomal triglyceride transfer protein (MTTP) inhibitor potentially for the treatment of type 2 diabetes.
T39303	CP-346086
	CP-346086 is a highly potent and orally bioavailable inhibitor of microsomal triglyceride transfer protein (MTP), exhibiting an IC50 value of 2.0 nM against both human and rodent MTP. This compound effectively reduces plasma levels of cholesterol and triglycerides when administered in vivo.

化合物

Cat.No: T27719

Synonym: SLx 4090,SLx4090,KD026,SLx-4090

Target: CETP

Lomitapide Mesylate

Cat.No: T2545

Synonym: 甲磺酸洛美他派,BMS-201038 mesylate,AEGR-733 mesylate

Target: CETP

Cat.No: T30506

Synonym: UNII-0Z473OO6GB,BMS212122,BMS 212122

Target: CETP

Cat.No: T15006

Synonym: CP742033,Slentrol

Target: Others, CETP

Cat.No: T31992

Target: CETP

Cat.No: T6267

Synonym: AEGR-733,洛美他派,BMS-201038

Target: CETP

Implitapide Racemate

Cat.No: T10504

Target: Others

Cat.No: T24223

Synonym: JTT-130,JTT130

CP-319340(free base)

Cat.No: T13418

Target: Others

Cat.No: T15570

Synonym: 英普他派,AEGR 427

Target: CETP

Cat.No: T16158

Target: Adenosine Receptor

Cat.No: T35005

Synonym: R-256918,JNJ-16269110,JNJ16269110,R256918,JNJ 16269110,R 256918

CP-346086 dihydrate

Cat.No: T38666

KD026-metabolite

Cat.No: T68375

Cat.No: T39303

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