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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T3477	E4CPG	GluR	Neuroscience
	E4CPG 是一种 I/II 组代谢型谷氨酸受体的拮抗剂，可抑制单突触后机制中突触后电流 (IPSC) 增强的成对脉冲比。
T41301	L-Cysteinesulfinic acid monohydrate	GluR	Neuroscience
	L-Cysteinesulfinic acid monohydrate 是代谢型谷氨酸受体 (mGluRs) 的有效激动剂，可以作用于 mGluR1，mGluR2，mGluR5，mGluR4，mGluR6 和 mGluR8，pEC50分别为 3.92，3.9，4.6，2.7，4.0，和 3.94。
T9011	VU0155094 ML 397,ML-397,VU 0155094,VU-0155094	GluR	Neuroscience
	VU0155094 (ML 397) 是一种正变构调节剂，对各种 III 组 mGluR 具有不同的活性
T23291	(S)-3-Hydroxyphenylglycine	GluR	Neuroscience
	(S)-3-Hydroxyphenylglycine 是 I 组代谢型谷氨酸受体 (mGluRs) 的激动剂。
T22711	DCB 3,3'-dichlorobenzaldazine	Others; GluR	Neuroscience; Others
	DCB (3,3'-dichlorobenzaldazine) 是 mGluR5 的变构配体，显示出 3,3'-二甲氧基苯扎嗪 (DMeOB) 的负调节作用。 DCB 在 3,3'-二氟苯扎嗪 (DFB) 的帮助下阻断 mGluR 的正变构调节。
T11032	DHPG (RS)-3,5-DHPG,DL-Α-(3,5-二羟基苯基)甘氨酸	GluR	Neuroscience
	DHPG ((RS)-3,5-DHPG) 是一种氨基酸，是选择性代谢型谷氨酸受体 mGluR 的激动剂，也是与磷脂酶 D 耦合的 mGluR 的有效拮抗剂。
T12772	(RS)-PPG	Others	Others
	(RS)-PPG is a potent and selective group III mGluRs agonist(EC50s of 5.2 μM, 4.7 μM, 185 μM, and 0.2 μM for hmGluR4a, hmGluR6, hmGluR7b, and hmGluR8a, respectively),with neuroprotective and anticonvulsive activity.
T10095	(2R,4R)-APDC	Others	Others
	(2R,4R)-APDC is a selective group II metabotropic glutamate receptors (mGluRs) agonist. It has anticonvulsant and neuroprotective effects.
T15692	L-AP4 L-APB,L-AP 4	GluR	Neuroscience
	L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).
T37127	L-AP4 monohydrate L-AP4 monohydrate
	L-AP4 (L-APB) monohydrate is a potent and specific agonist for the group III mGluRs, with EC50s of 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6 and mGlu7 receptors, respectively[1][2]. L-AP4 (5-30 μg, intrathecal inhection 4-5 days) significantly increases the paw withdrawal threshold in response to application of von Frey filaments in eight nerve-ligated rats in a dose-dependent manner. Intrathecal administration of different doses of L-AP4 is not associated with any evident motor dysfunctio...

化合物

L-Cysteinesulfinic acid monohydrate

Synonym: ML 397,ML-397,VU 0155094,VU-0155094

Target: GluR

(S)-3-Hydroxyphenylglycine

Synonym: 3,3'-dichlorobenzaldazine

Target: Others, GluR

DHPG

Cat.No: T11032

Synonym: (RS)-3,5-DHPG,DL-Α-(3,5-二羟基苯基)甘氨酸

Synonym: L-APB,L-AP 4

Target: GluR

L-AP4 monohydrate

Cat.No: T37127

Synonym: L-AP4 monohydrate

Target:

Cat. No.	Product Name	Target	Signaling Pathways
T5083	L-Cysteic acid monohydrate L-磺基丙氨酸一水合物,3-Sulfo-L-alanine Monohydrate	Endogenous Metabolite; GluR	Metabolism; Neuroscience
	L-Cysteic acid monohydrate (3-Sulfo-L-alanine Monohydrate) 是内源性代谢产物的一种。
T11803	L-Cysteinesulfinic acid	Others	Others
	L-Cysteinesulfinic acid is a potent agonist at several rat metabotropic glutamate receptors (mGluRs, pEC50s of 3.92±0.03, 4.6±0.2, 3.9±0.2, 2.7±0.2, 4.0±0.2, and 3.94±0.08 for mGluR1, mGluR5, mGluR2, mGluR4, mGluR6, and mGluR8, respectively).

天然产物

L-Cysteic acid monohydrate

Cat.No: T5083

Synonym: L-磺基丙氨酸一水合物,3-Sulfo-L-alanine Monohydrate

Target: Endogenous Metabolite, GluR

L-Cysteinesulfinic acid

Cat.No: T11803

Synonym:

Target: Others

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