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抑制剂 & 化合物

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
TQ0105	CAY10650	Phospholipase	Metabolism
	CAY10650 是高效的胞浆磷脂酶A2α抑制剂，IC50=12 nM，能够抑制脂滴形成和 PGE2 分泌。
T19033	Nile Red Phenoxazone 9,尼罗红,Nile Blue A oxazone	Others	Others
	Nile Red (Nile Blue A oxazone) 是一种选择性疏水性荧光染料，针对细胞内脂质小滴和中性脂质。它在所有有机溶剂中均具有强烈的荧光性，其荧光颜色范围从金黄色到深红色。
T36959	BODIPY 558/568 C12 Red C12
	BODIPY 558/568 C12 is a fatty acid-conjugated fluorescent probe for lipid droplets. [1] [2] It displays excitation/emission maxima of 558/568 nm, respectively, and has been used to monitor the localization and dynamics of lipid droplets in live cells.
T33674	NIM-7 NIM7
	NIM-7 is a fluorescent probe, allowing lipid droplets and lysosomes to be labelled simultaneously and with high specificity, being visualized readily through yellow and red fluorescence, using different excitation and detection channels.
T82894	BETA-1
	BETA-1作为首个分子内电荷转移聚集诱导发射集成分子(TICT-AIE integration molecule)，在脂滴(LD)内呈现青色荧光，在线粒体中显现红色荧光。该分子适用于脂滴与线粒体的体内外同步双色成像。
T62029	ML261
	ML261 是肝脂滴形成的抑制剂，IC50值为 69.7 nM。ML261 在非酒精性脂肪性肝病 (NAFLD) 和炎症中具有研究价值。
T81348	PTZ-LD
	PTZ-LD是一种phenothiazine衍生的荧光探针，专门用于检测脂滴(LDs)。在LDs中，PTZ-LD展示出显著的高特异性发射(Ex/Em=488/570-620 nm)。此探针还可以应用于糖尿病性白内障(DC)的研究工作。
T35800	MD001
	MD001 is a dual agonist of peroxisome proliferator-activated receptor α (PPARα) and PPARγ.1 It binds to PPARα and PPARγ (Kds = 9.55 and 0.14 μM, respectively) but does not bind to PPARβ/δ at concentrations up to 500 μM. It increases transcriptional activity of PPARα and PPARγ in a cell-based luciferase reporter assay when used at a concentration of 10 μM. MD001 (10 μM) increases expression of PPARα, PPARγ, and retinoid X receptor (RXR), as well as PPARα and PPARγ target genes, in HepG2 cells. It...

化合物

CAY10650

Cat.No: TQ0105

Synonym:

Target: Phospholipase

Nile Red

Cat.No: T19033

Synonym: Phenoxazone 9,尼罗红,Nile Blue A oxazone

Cat. No.	Product Name	Target	Signaling Pathways
TN3882	Dodoviscin A	cAMP; Tyrosinase; transporter	GPCR/G Protein; Metabolism; Proteases/Proteasome
	Dodoviscin A may be a new promising pigmentation-altering agent for cosmetic and therapeutic applications, it can inhibit melanin biosynthesis induced by 3-isobutyl-1-methylxanthine and PD98059.Dodoviscin A can promote adipocyte differentiation as charact