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Search Results for " limonoid "

3

抑制剂 & 化合物

11

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T34510	Sandoricin
	Sandoricin is a limonoid from the seed of Sandoricum koetjape.
T33713	Nomilinic acid glycoside Nomilinic acid 17-O-beta-D-glucoside
	Nomilinic acid glycoside is a limonoid glucoside from the peel of Citrus tangerina.
T26709	Azadirone
	Azadirone is a limonoid tetranortriterpene. Azadirone can sensitize cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) through ROS-ERK-CHOP-mediated up-regulation of DR4 and DR5 signaling, down-regulation of cell survival prot

化合物

Cat.No: T34510

Nomilinic acid glycoside

Cat.No: T33713

Synonym: Nomilinic acid 17-O-beta-D-glucoside

Cat.No: T26709

Cat. No.	Product Name	Target	Signaling Pathways
TN6730	Epoxyazadiradione	NF-κB	NF-κB
	Epoxyazadiradione 是从印楝果实中得到的柠檬苦素。它能够可逆的、非竞争性的抑制人类、约氏疟原虫、疟原虫的互变异构酶活性。它具有抗疟原虫和人类 MIF 诱导的促炎反应的潜力。
T3672	Nomilin	MAPK	MAPK
	Nomilin 是一种柠檬苦素类化合物，从柑桔类提取物中获得，是抗肥胖症和降糖药。
TN6729	Azadiradione AZD	Others	Others
	Azadiradione (AZD) 是 HSF1的一种，是由印楝树中提取得到，具有一定生物活性的柠檬苦素。
T21883	Gedunin	HSP	Cytoskeletal Signaling; Metabolism
	Gedunin 是从印楝种子中提取的一种重要柠檬苦素，具有抗癌、抗病毒、抗炎和杀虫活性。它可阻断 SARS-CoV-2 病毒进入人宿主细胞，用于 COVID-19 研究。它是Hsp90抑制剂，诱导 Hsp90 依赖的蛋白降解，抑制卵巢癌细胞增殖。
TN6989	Isotoosendanin 异川楝素,(1S,2S,4R,5S,6R,9S,10S,11R,13R,18S,20R)-20-(acetyloxy)-6-(furan-3-yl)-11,15,18-trihydroxy-5,10,14-trimethyl-3,8-dioxo-16-oxapentacyclo[12.3.3.01,13.02,1?.0?,?]icosan-4-yl acetate	Others	Others
	Isotoosendanin ((1S,2S,4R,5S,6R,9S,10S,11R,13R,18S,20R)-20-(acetyloxy)-6-(furan-3-yl)-11,15,18-trihydroxy-5,10,14-trimethyl-3,8-dioxo-16-oxapentacyclo[12.3.3.01,13.02,1?.0?,?]icosan-4-yl acetate) 是一种从楝树 Melia toosendan 果实中分离出的柠檬苦素类天然产物，具有抗炎和镇痛作用。
TN4348	Jangomolide	Others	Others
	Jangomolide, a novel limonoid from flacourtia jangomas.
TN4135	Glaucin B	Others	Others
	Glaucin B is a new bitter limonoid.
T34488	Salannin Margosan-O,Azadriactin,Neem extract
	Salannin is a limonoid from Azadirachta indica A. Juss.
T33712	Nomilin glucoside Nomilin 17-O-beta-D-glucopyranoside
	Nomilin glucoside is a limonoid glucoside from the peel of Citrus tangerina.
T31243	Deacetylgedunin 7-Deacetylgedunin
	Deacetylgedunin is a limonoid that is the 7-deacetyl derivative of gedunin. It has been isolated from Azadirachta indica.
T14368	Azadirachtin B	Others	Others
	Azadirachtin B, a limonoid derived from the seed kernels of Azadirachta indica, exhibits a broad spectrum of biochemical activities, including insecticidal, nematocidal, anticancer, anti-inflammatory, antiviral, and osteogenic effects. It is effective against the Epstein-Barr virus early antigen (EBV-EA), enhances alkaline phosphatase (ALP) activity, and promotes osteoblast differentiation[1][2][3].

天然产物

Epoxyazadiradione

Cat.No: TN6730

Target: NF-κB

Cat.No: T3672

Target: MAPK

Cat.No: TN6729

Synonym: AZD

Target: Others

Cat.No: T21883

Target: HSP

Cat.No: TN6989

Synonym: 异川楝素,(1S,2S,4R,5S,6R,9S,10S,11R,13R,18S,20R)-20-(acetyloxy)-6-(furan-3-yl)-11,15,18-trihydroxy-5,10,14-trimethyl-3,8-dioxo-16-oxapentacyclo[12.3.3.01,13.02,1?.0?,?]icosan-4-yl acetate

Target: Others

Cat.No: TN4348

Target: Others

Cat.No: TN4135

Target: Others

Cat.No: T34488

Synonym: Margosan-O,Azadriactin,Neem extract

Nomilin glucoside

Cat.No: T33712

Synonym: Nomilin 17-O-beta-D-glucopyranoside

Deacetylgedunin

Cat.No: T31243

Synonym: 7-Deacetylgedunin

Cat.No: T14368

Target: Others

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