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23

抑制剂 & 化合物

4

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T31833	FMC 23509 FMC-23509,FMC23509,Juvenile hormone analog fmc 23509,Crd 9499
	FMC 23509 is a bioactive chemical.
T16044	Methoprene 烯虫酯,ZR-515	Others	Others
	Methoprene (ZR-515) 是一种保幼激素模拟物和一种生物杀虫剂。Methoprene 作为昆虫生长调节剂，干扰昆虫的生命周期并阻止其成熟或繁殖。
TP1571L	Allatostatin II acetate(123374-34-5 free base)	Others	Others
	Allatostatin II acetate(123374-34-5 free base) 用于昆虫保幼激素合成抑制剂。
T16696	Pyriproxyfen S-31183,吡丙醚	Others	Others
	Pyriproxyfen (S-31183) 是昆虫生长调节剂，具有杀虫的作用，属保幼激素类似物。
TP1605L1	Allatostatin IV TFA(123338-13-6 free base)	Others	Others
	Allatostatin IV TFA(123338-13-6 free base) 是一种八肽胺，是在昆虫中发现的抑制（allatostatins）或刺激（allatotropins）保幼激素（JH）合成的调节肽家族的成员。
TP1658L	Type A Allatostatin I acetate Type A Allatostatin I acetate(123209-95-0 free base)	Others	Others
	Type A Allatostatin I acetate(123209-95-0 free base) 是一种十三肽。 Allatostatin 是多效性神经肽，用于抑制昆虫保幼激素的合成。
T19752	S-Methoprene ZR2458,ZR 2458,ZR-2458,(+)-Methoprene,Preco
	S-Methoprene (ZR2458) 是保幼激素的类似物，可用作杀虫剂。 S-Methoprene 改变细胞色素氧化酶的氧化还原活性并诱导雄性分化。
T37445	Etanercept	TNF	Apoptosis
	Etanercept is a dimeric fusion protein that serves as a competitive TNF inhibitor by binding to TNF. It effectively inhibits the binding of both TNF-α and TNF-β to the TNF receptors on cell surfaces, thereby rendering TNF biologically inactive. Etanercept has demonstrated efficacy in treating rheumatoid arthritis, juvenile idiopathic arthritis, and plaque psoriasis.
T32327	Juvocimene I Juvocimene 1
	Juvocimene I and II isolated from the essential oil of sweet basil,Ocimum basilicum L are potent juvenile hormone mimics.
T31138	Cyclopren JH-149,JH149,JH 149
	Cyclopren can be used as a juvenile hormone.
T29769	AI 3-34137 AI3-34137,AI-3-34137
	AI 3-34137 is a juvenile hormone analog.
TP1571	Allatostatin II
	Allatostatin II is an Inhibitors of juvenile hormone synthesis in insects.
T32328	Juvocimene II
	Juvocimene I and II are isolated from the essential oil of sweet basil,Ocimum basilicum L are effective juvenile hormone mimics.
TP1658	Type A Allatostatin I
	Type A Allatostatin I is a tridecapeptide that falls under the category of pleiotropic neuropeptides. These neuropeptides are known for their ability to inhibit the synthesis of juvenile hormone in insects.
TP1030	Thymus factor X TFX-Jelfa,胸腺因子X
	Thymic factor X (TFX-Jelfa) is an aqueous extract from the thymus of a juvenile calf and is a natural stimulator of lymphocyte function.
TP1605	Allatostatin IV
	Allatostatin IV, an octapeptide amine, is a member of the allatoregulatory peptide family found in insects which either inhibit (allatostatins) or stimulate (allatotropins) juvenile hormone (JH) synthesis.
T35873	C19 Ceramide (d18:1/19:0) C19 Ceramide (d18:1/19:0)
	C19 Ceramide is a naturally occurring ceramide that has been found in J. juncea extracts as well as rat brain and mouse heart.[1],[2],[3] It is elevated in adult and decreased in juvenile whole rat brain extracts by 114 and 37%, respectively, following chronic ethanol exposure.[2] C19 Ceramide is also increased in mouse hearts following administration of angiotensin II.[3]
T80916	Type A Allatostatin III
	Type A Allatostatin III (allatostatin 3) 是抑制幼年雌性蟑螂激素合成的具血脑屏障透过性和可逆性神经肽，可应用于杀虫剂研究。
T70358	Gepotidacin mesylate dihydrate
	Gepotidacin mesylate dihydrate, also known as GSK-2140944 mesylate dihydrate, is a potent Type II DNA topoisomerase inhibitor. Gepotidacin mesylate dihydrate is a novel antibacterial drug candidate. Gepotidacin mesylate dihydrate Demonstrates Absence of Fluoroquinolone-Like Arthropathy in Juvenile Rats. Gepotidacin mesylate dihydrate is efficacious in a nonhuman primate model of pneumonic plague. When tested against Gram-negative (n = 333) and Gram-positive (n = 225) anaerobes by agar dilution, ...
T76751	Lenzilumab
	Lenzilumab (KB 003) 是一种靶向CSF2/GM-CSF 的人源化单克隆抗体，可用于 COVID-19、慢性粒单核细胞白血病 (CMML) 和幼年粒单核细胞白血病 (JMML) 研究。
T71490	Gepotidacin hydrochloride
	Gepotidacin hydrochloride, also known as GSK-2140944 hydrochloride, is a potent Type II DNA topoisomerase inhibitor. Gepotidacin hydrochloride is a novel antibacterial drug candidate. Gepotidacin hydrochloride Demonstrates Absence of Fluoroquinolone-Like Arthropathy in Juvenile Rats. Gepotidacin hydrochloride is efficacious in a nonhuman primate model of pneumonic plague. When tested against Gram-negative (n = 333) and Gram-positive (n = 225) anaerobes by agar dilution, Gepotidacin hydrochloride...
T78241	Asfotase alfa ENB-0040
	Asfotase alfa (ENB-0040) 是一款针对骨骼的基因重组糖蛋白。该药物提升了Akp2−/−基因敲除小鼠的存活率、骨矿化及骨骼生长，并且缓解了脚部、胸部、下肢及颌骨矿化缺损。它主要用于对围产期、婴幼儿及青少年型低磷酸酶血症(HPP)进行研究。
T37632	TFM
	TFM is a piscicide.1It is toxic to sea lamprey (P. marinus) with LC50values ranging from 1.97 to 2.11 and 2.05 to 2.21 mg/L for sac and swim-up fry, respectively, 1.6 to 2.45 mg/L for juveniles, and 1.6 to 1.63 mg/L for adults. It is also toxic to juvenile lake sturgeon (A. fulvescens) less than 100 mm in size but not to a variety of other fish species. TFM (50 μM) uncouples oxidative phosphorylation by 22 and 28% in isolated sea lamprey and rainbow trout (O. mykiss) liver, respectively.2Formula...

化合物

Cat.No: T31833

Synonym: FMC-23509,FMC23509,Juvenile hormone analog fmc 23509,Crd 9499

Cat.No: T16044

Synonym: 烯虫酯,ZR-515

Target: Others

Allatostatin II acetate(123374-34-5 free base)

Cat.No: TP1571L

Target: Others

Cat.No: T16696

Synonym: S-31183,吡丙醚

Target: Others

Allatostatin IV TFA(123338-13-6 free base)

Cat.No: TP1605L1

Target: Others

Type A Allatostatin I acetate

Cat.No: TP1658L

Synonym: Type A Allatostatin I acetate(123209-95-0 free base)

Target: Others

Cat.No: T19752

Synonym: ZR2458,ZR 2458,ZR-2458,(+)-Methoprene,Preco

Cat.No: T37445

Target: TNF

Cat.No: T32327

Synonym: Juvocimene 1

Cat.No: T31138

Synonym: JH-149,JH149,JH 149

Cat.No: T29769

Synonym: AI3-34137,AI-3-34137

Allatostatin II

Cat.No: TP1571

Cat.No: T32328

Type A Allatostatin I

Cat.No: TP1658

Thymus factor X

Cat.No: TP1030

Synonym: TFX-Jelfa,胸腺因子X

Allatostatin IV

Cat.No: TP1605

C19 Ceramide (d18:1/19:0)

Cat.No: T35873

Synonym: C19 Ceramide (d18:1/19:0)

Type A Allatostatin III

Cat.No: T80916

Gepotidacin mesylate dihydrate

Cat.No: T70358

Cat.No: T76751

Gepotidacin hydrochloride

Cat.No: T71490

Cat.No: T78241

Synonym: ENB-0040

Cat.No: T37632

Cat. No.	Product Name	Target	Signaling Pathways
T83531	(Rac)-Juvenile hormone III
	(Rac)-Juvenile hormone III，一种自法脂酸分离的天然产物，作为幼体激素的同源物具有最广泛分布。
T21130	Precocene II 早熟素Ⅱ,AI3-36847,Ageratochromene,BRN 0160683	Others	Others
	Precocene II (Ageratochromene) 是一种抗异体激素化合物，可抑制保幼激素的生物合成。 Precocene II 具有杀虫、抗真菌、抗菌和抗氧化活性。
T4776	Glycerol Glycerin,甘油	Endogenous Metabolite	Metabolism
	Glycerol 是甘油三酯（即脂肪和油）和磷脂的重要成分。它在食品工业中被广泛用作甜味剂和保湿剂以及药物制剂。
T32326	Juvabione
	Juvabione is the methyl ester of todomatuic acid, both of which are sesquiterpenes (C15) found in the wood of true firs of the genus Abies. They exist as part of a mixture of sesquiterpenes based on the bisabolane scaffold. Sesquiterpenes of this family,

天然产物

(Rac)-Juvenile hormone III

Cat.No: T83531

Cat.No: T21130

Synonym: 早熟素Ⅱ,AI3-36847,Ageratochromene,BRN 0160683

Target: Others

Cat.No: T4776

Synonym: Glycerin,甘油

Target: Endogenous Metabolite

Cat.No: T32326

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