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21

抑制剂 & 化合物

1

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T0863	Idoxuridine IDU,碘苷,SKF 14287,5-Iodo-2′-deoxyuridine,NSC 39661,5-IUdR,Dendrid	Antifection; HSV	Microbiology/Virology
	Idoxuridine (Dendrid) 是一种抑制病毒 DNA 合成的脱氧尿苷类似物，用作抗病毒剂。
T1576	Iopamidol SQ-13396,Niopam,Iopamiron,Iopamiro,碘帕醇,B-15000,Isovue	Others	Others
	Iopamidol (SQ-13396) 是一种 benzenedicarboxamide 化合物。它具有放射性不透明介质、环境污染物和异种生物的作用。
T19376	Ioversol MP-328,碘佛醇	Others	Others
	Ioversol (MP-328) 是一种非离子碘化造影剂 (CM)，不损伤动物的血脑屏障 (BBB)，可用于动物实验的 CT 扫描或 x-ray。
T0960	Iopanoic acid 碘番酸,Iodopanoic acid,Acidum iopanoicum	Others	Others
	Iopanoic acid (Acidum iopanoicum) 是5'-脱碘酶的抑制剂，也是一种碘造影剂。
T1395	Diatrizoic Acid Diatrizoate,泛影酸,Amidotrizoic acid	Apoptosis; Others	Apoptosis; Others
	Diatrizoic Acid (Amidotrizoic acid) 是一种有机碘化不透射线 X 射线造影剂，用于放射诊断，具有对气道进行放射照相成像的潜力。它通过钙失调诱导线粒体更新和氧化应激，激活细胞凋亡。
T8628	2,4,6-Triiodophenol	Others	Others
	2,4,6-Triiodophenol 用作废水氯化过程中形成的碘化消毒副产物。它也被用作一种有效的甲状腺干扰化学物质和研究脱碘酶。
T0503	Meglumine Meglumin,Methylglucamin,葡甲胺,葡萄糖甲胺,Methylglucamine	Others	Others
	Meglumine (Meglumin) 是一种氨基糖，来源于山梨糖醇。其中常在药物中用作赋形剂，并与碘代化合物葡甲胺和碘帕胺葡甲胺等造影剂中的碘化化合物一起使用。
T20637	Diatrizoate meglumine Reno,Renografin,Renovist,泛影葡胺,Hypaque,Renocal,Sinografin	Others	Others
	Diatrizoate meglumine (Renocal) 是泛影酸盐的葡甲胺盐，它是一种有机的、碘化的、不透射线的 X 射线造影剂，用于放射诊断。
T1319	Sodium diatrizoate Diatrizoic acid sodium salt,Sodium amidotrizoate,Hypaque sodium,泛影酸钠,Diatrizoate sodium,amidotrizoate sodium,Triombrin	Apoptosis; Others	Apoptosis; Others
	Sodium diatrizoate (Hypaque sodium) 是一种碘化不透射线 X 射线造影剂，在血管造影、尿路造影和放射造影中用作诊断辅助工具。它可通过钙失调诱导线粒体更新和氧化应激，激活细胞凋亡。
T8963	CYM2503	Neuropeptide Y Receptor	GPCR/G Protein; Neuroscience
	CYM2503 是 GAL2 受体的正变构调节剂 (PAM)，可在体外增强甘丙肽诱导的 IP1 产生。它对受体的正构甘丙肽结合位点没有亲和力（通过其无法置换碘化甘丙肽或自行诱导 IP1 积累来衡量）。
T32178	Ioglucomide MP 8000,MP-8000
	Ioglucomide is an iodinated nonionic contrast medium directed primarily toward myelographic use.
T28979	TISCH
	TISCH is a potent and selective iodinated ligand for CNS D1 dopamine receptor.
T32182	Iopydone NSC 135284,NSC135284,NSC-135284,Hytrast,Iopydonum
	Iopydone is an iodinated contrast dye.
T40723	Bromoiodoacetamide
	Bromoiodoacetamide, an iodinated haloacetamide (I-HAcAm) compound, exhibits cytotoxic properties. Its mechanism of action involves the accumulation of reactive oxygen species (ROS) and induction of apoptosis in HepG-2 cells.
T40827	Bromoiodoacetic acid
	Bromoiodoacetic acid is a disinfection byproduct (DBP) found in finished drinking waters, belonging to the iodinated haloacids.
T29592	Acetrizoate sodium Reopak,Diaginol,MP1023,MP 1023,MP-1023
	Acetrizoate sodium 又称醋碘苯酸的钠盐，可用作高渗透压、水溶性、碘化的放射造影剂。
T37668	CAY10448 CAY10448
	Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Capsaicin signals are transduced by a heat-activated ion channel, the vanilloid receptor 1 (VR1), or transient receptor potential vanilloid 1 (TRPV1). CAY10448 is an iodinated nonivamide, a potent capsaicin receptor antagonist with an IC50 value of approximately 10 nM.
T19377	Ioxilan	Others	Others
	Ioxilan is a low-osmolar, nonionic, and tri-iodinated diagnostic contrast agent used for excretory urography and contrast-enhanced computed tomographic (CECT) imaging of the head and body. Intravascularly injected causes opacification of vessels, allowing for radiographic visualization of internal structures until significant hemodilution occurs.
T74922	ICy-OH
	ICy-OH，一种有效的碘化光敏剂化学抗癌剂。该化合物适用于深层组织成像（λex=640 nm，λem=690-740 nm），并能通过细胞焦亡(pyroptosis)途径，选择性诱导胰腺癌细胞死亡。
T61492	Idoxuridine hydrate
	Idoxuridine hydrate (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is a competitive inhibitor of phosphorylases. As an iodinated thymidine analogue, it effectively inhibits DNA polymerase and hinders viral replication, making it useful in the treatment of viral eye infections such as herpes simplex keratitis. Against feline herpesvirus, Idoxuridine has been found to have an IC50 value of 4.3 μM [1].
T32091	Hofman's Violet
	Hoffman's violet is specific stains for animal chromosomes. Iodinated alcohol after staining can be substituted with various acids, both organic as well as inorganic, all of which act as trapping agent preventing leaching of the dye that binds with the ch

化合物

Cat.No: T0863

Synonym: IDU,碘苷,SKF 14287,5-Iodo-2′-deoxyuridine,NSC 39661,5-IUdR,Dendrid

Target: Antifection, HSV

Cat.No: T1576

Synonym: SQ-13396,Niopam,Iopamiron,Iopamiro,碘帕醇,B-15000,Isovue

Target: Others

Cat.No: T19376

Synonym: MP-328,碘佛醇

Target: Others

Cat.No: T0960

Synonym: 碘番酸,Iodopanoic acid,Acidum iopanoicum

Target: Others

Diatrizoic Acid

Cat.No: T1395

Synonym: Diatrizoate,泛影酸,Amidotrizoic acid

Target: Apoptosis, Others

2,4,6-Triiodophenol

Cat.No: T8628

Target: Others

Cat.No: T0503

Synonym: Meglumin,Methylglucamin,葡甲胺,葡萄糖甲胺,Methylglucamine

Target: Others

Diatrizoate meglumine

Cat.No: T20637

Synonym: Reno,Renografin,Renovist,泛影葡胺,Hypaque,Renocal,Sinografin

Target: Others

Sodium diatrizoate

Cat.No: T1319

Synonym: Diatrizoic acid sodium salt,Sodium amidotrizoate,Hypaque sodium,泛影酸钠,Diatrizoate sodium,amidotrizoate sodium,Triombrin

Target: Apoptosis, Others

Cat.No: T8963

Target: Neuropeptide Y Receptor

Cat.No: T32178

Synonym: MP 8000,MP-8000

Cat.No: T28979

Cat.No: T32182

Synonym: NSC 135284,NSC135284,NSC-135284,Hytrast,Iopydonum

Bromoiodoacetamide

Cat.No: T40723

Bromoiodoacetic acid

Cat.No: T40827

Acetrizoate sodium

Cat.No: T29592

Synonym: Reopak,Diaginol,MP1023,MP 1023,MP-1023

Cat.No: T37668

Synonym: CAY10448

Cat.No: T19377

Target: Others

Cat.No: T74922

Idoxuridine hydrate

Cat.No: T61492

Hofman's Violet

Cat.No: T32091

Cat. No.	Product Name	Target	Signaling Pathways
T4461	3,5-Diiodo-L-thyronine 3,5-二碘-L-甲状腺素,Diiodothyronine	Thyroid hormone receptor(THR); Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	3,5-Diiodo-L-thyronine (Diiodothyronine) 是内源性代谢产物的一种。

天然产物

3,5-Diiodo-L-thyronine

Cat.No: T4461

Synonym: 3,5-二碘-L-甲状腺素,Diiodothyronine

Target: Thyroid hormone receptor(THR), Endogenous Metabolite

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