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Search Results for " histone h3 phosphorylation "

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Cat. No.	Product Name	Target	Signaling Pathways
TQ0059	Ilorasertib ABT-348	VEGFR; FLT; c-RET; PDGFR; Aurora Kinase	Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
	Ilorasertib (ABT-348) 是一种 ATP 竞争性多靶点激酶抑制剂，可抑制 Aurora A、Aurora B 和Aurora C，IC50值为120 nM、7 nM 和1 nM。它还抑制 RET 酪氨酸激酶、PDGFRβ 和 Flt1，IC50为7 nM、3 nM 和 32 nM。
T36576	Histone H3 (21-44)-GK-biotin (trifluoroacetate salt) Histone H3 (21-44)-GK-biotin (trifluoroacetate salt)
	Histone H3 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and 3.2 sequences and is biotinylated via a C-terminal GK linker. Histone H3 (21-44) contains a lysine residue at position 23 that is subject to acetylation, an arginine at position 26 subject to methylation, and a serine at position 28 subject to phosphorylation, as well as lysine residues at positions 27 and 36 that are subject to methylation and acetylation....
T36979	Histone H3 (21-44)-GK-biotin amide (trifluoroacetate salt) Histone H3 (21-44)-GK-biotin amide (trifluoroacetate salt)
	Histone H3 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.3 sequence and is biotinylated via a C-terminal GK linker. Unlike histone H3.1 and H3.2, the histone H3.3 variant contains a serine residue at position 31 that is phosphorylated during late prometaphase and metaphase of mitosis. Histone H3 (21-44) also contains lysine residues at positions 23, 27, and 36 that are subject to methylation and acetylation, all of whi...
T68458	Fostriecin (free base)
	Fostriecin (free base) is an inhibitor of the serine/threonine protein phosphatases 2A (PP2A) and 4 (PP4) (IC50s = 3.2 and 3 nM, respectively). It less effectively inhibits topoisomerase II and PP1 (IC50s = 40 and 131 μM, respectively) and does not inhibit PP2B. Through its effects on protein phosphatases, fostriecin increases the level of histone H3 phosphorylation and may alter epigenetic regulation of cell proliferation. On a related note, fostriecin was first identified as an antitumor antib...

化合物

Cat.No: TQ0059

Synonym: ABT-348

Target: VEGFR, FLT, c-RET, PDGFR, Aurora Kinase

Histone H3 (21-44)-GK-biotin (trifluoroacetate salt)

Cat.No: T36576

Synonym: Histone H3 (21-44)-GK-biotin (trifluoroacetate salt)

Histone H3 (21-44)-GK-biotin amide (trifluoroacetate salt)

Cat.No: T36979

Synonym: Histone H3 (21-44)-GK-biotin amide (trifluoroacetate salt)

Fostriecin (free base)

Cat.No: T68458

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