2
2
4
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T39526 |
Decanoyl-RVKR-CMK TFA
DecRVKRcmk TFA,Decanoyl-RVKR-CMK TFA |
||
Decanoyl-RVKR-CMK (DecRVKRcmk) TFA effectively hinders the processing of over-expressed gp160 and suppresses HIV-1 replication. | |||
TP2038 |
Decanoyl-RVKR-CMK
|
||
Subtilisin/Kex2p-like proprotein convertase inhibitor; blocks activity of all seven convertases (PC1, PC2, PC4, PACE4, PC5, PC7 and furin). Abolishes proET-1 processing in endothelial cells; inhibits regulated secretion of the neuronal polypeptide VGF in |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3122 |
Fangchinoline
Tetrandrine B,防己诺林碱,(+)-Limacine,Hanfangichin B,防己醇灵,(+)-Fangchinoline |
Apoptosis; FAK; HIV Protease; Autophagy | Angiogenesis; Apoptosis; Autophagy; Cytoskeletal Signaling; Microbiology/Virology; Proteases/Proteasome; Tyrosine Kinase/Adaptors |
Fangchinoline (Tetrandrine B) 是从Stephaniatetrandra 中分离出来的,一种具有广泛生物学活性的天然产物。它是新型HIV-1抑制剂,通过损害 gp160 蛋白水解过程来抑制 HIV-1 复制。它靶向Focal adhesion kinase (FAK)并抑制肿瘤细胞中 FAK 介导的的信号传导途径。 | |||
T2809 |
(R)-Fangchinoline
防己醇灵,Thaligine,(+)-Thalrugosine,Demethyl tetrandrine |
FAK; Antibacterial; Antibiotic | Angiogenesis; Cytoskeletal Signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors |
(R)-Fangchinoline ((+)-Thalrugosine) 是一种来自Stephania 属的生物碱,具有抗菌和降血压活性。它可用作中药,可用于发烧,腹泻,消化不良和泌尿疾病的研究。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00644 |
Aminopeptidase A Protein, Human, Recombinant (His)
APA,glutamyl aminopeptidase,ENPEP,gp160,CD... |
Human | Baculovirus Insect Cells |
Aminopeptidase A Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 107.2 kDa and the accession number is Q07075. | |||
TMPY-01558 |
HIV-1 (group N, strain 06CM-U14296) gp160 (gp120 subunit) Protein (His)
|
HIV | HEK293 Cells |
HIV-1 (group N, strain 06CM-U14296) gp160 (gp120 subunit) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.4 kDa. | |||
TMPY-00302 |
HIV-1 (group M, subtype A, isolate 92RW020) gp160 (gp120 subunit) Protein (His)
|
HIV | HEK293 Cells |
HIV-1 (group M, subtype A, isolate 92RW020) gp160 (gp120 subunit) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.2 kDa and the accession number is Q6BC58. | |||
TMPJ-01313 |
HIV-1 gp120 Protein (His)
Envelope glycoprotein gp120,Surface protein gp<... |
HIV | HEK293 Cells |
Envelope glycoprotein gp160 is single-pass type I membrane protein. The mature envelope protein (Env) consists of a homotrimer of non-covalently associated gp120-gp41 heterodimers. It is cleaved into the following 2 chains: glycoprotein 120 and transmembrane protein gp41. The resulting complex protrudes from the virus surface as a spike. The 17 amino acids long immunosuppressive region is present in many retroviral envelope proteins. Synthetic peptides derived from this relatively conserved sequ... |