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2

抑制剂 & 化合物

2

天然产物

4

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T39526 Decanoyl-RVKR-CMK TFA

DecRVKRcmk TFA,Decanoyl-RVKR-CMK TFA

Decanoyl-RVKR-CMK (DecRVKRcmk) TFA effectively hinders the processing of over-expressed gp160 and suppresses HIV-1 replication.
TP2038 Decanoyl-RVKR-CMK

Subtilisin/Kex2p-like proprotein convertase inhibitor; blocks activity of all seven convertases (PC1, PC2, PC4, PACE4, PC5, PC7 and furin). Abolishes proET-1 processing in endothelial cells; inhibits regulated secretion of the neuronal polypeptide VGF in

化合物

Decanoyl-RVKR-CMK TFA
Cat.No: T39526
Synonym: DecRVKRcmk TFA,Decanoyl-RVKR-CMK TFA
Target:
Decanoyl-RVKR-CMK
Cat.No: TP2038
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T3122 Fangchinoline

Tetrandrine B,防己诺林碱,(+)-Limacine,Hanfangichin B,防己醇灵,(+)-Fangchinoline

Apoptosis; FAK; HIV Protease; Autophagy Angiogenesis; Apoptosis; Autophagy; Cytoskeletal Signaling; Microbiology/Virology; Proteases/Proteasome; Tyrosine Kinase/Adaptors
Fangchinoline (Tetrandrine B) 是从Stephaniatetrandra 中分离出来的,一种具有广泛生物学活性的天然产物。它是新型HIV-1抑制剂,通过损害 gp160 蛋白水解过程来抑制 HIV-1 复制。它靶向Focal adhesion kinase (FAK)并抑制肿瘤细胞中 FAK 介导的的信号传导途径。
T2809 (R)-Fangchinoline

防己醇灵,Thaligine,(+)-Thalrugosine,Demethyl tetrandrine

FAK; Antibacterial; Antibiotic Angiogenesis; Cytoskeletal Signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors
(R)-Fangchinoline ((+)-Thalrugosine) 是一种来自Stephania 属的生物碱,具有抗菌和降血压活性。它可用作中药,可用于发烧,腹泻,消化不良和泌尿疾病的研究。

天然产物

Fangchinoline
Cat.No: T3122
Synonym: Tetrandrine B,防己诺林碱,(+)-Limacine,Hanfangichin B,防己醇灵,(+)-Fangchinoline
Target: Apoptosis, FAK, HIV Protease, Autophagy
(R)-Fangchinoline
Cat.No: T2809
Synonym: 防己醇灵,Thaligine,(+)-Thalrugosine,Demethyl tetrandrine
Target: FAK, Antibacterial, Antibiotic
Cat. No. Product Name Species Expression System
TMPY-00644 Aminopeptidase A Protein, Human, Recombinant (His)

APA,glutamyl aminopeptidase,ENPEP,gp160,CD...

Human Baculovirus Insect Cells
Aminopeptidase A Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 107.2 kDa and the accession number is Q07075.
TMPY-01558 HIV-1 (group N, strain 06CM-U14296) gp160 (gp120 subunit) Protein (His)

HIV HEK293 Cells
HIV-1 (group N, strain 06CM-U14296) gp160 (gp120 subunit) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.4 kDa.
TMPY-00302 HIV-1 (group M, subtype A, isolate 92RW020) gp160 (gp120 subunit) Protein (His)

HIV HEK293 Cells
HIV-1 (group M, subtype A, isolate 92RW020) gp160 (gp120 subunit) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.2 kDa and the accession number is Q6BC58.
TMPJ-01313 HIV-1 gp120 Protein (His)

Envelope glycoprotein gp120,Surface protein gp<...

HIV HEK293 Cells
Envelope glycoprotein gp160 is single-pass type I membrane protein. The mature envelope protein (Env) consists of a homotrimer of non-covalently associated gp120-gp41 heterodimers. It is cleaved into the following 2 chains: glycoprotein 120 and transmembrane protein gp41. The resulting complex protrudes from the virus surface as a spike. The 17 amino acids long immunosuppressive region is present in many retroviral envelope proteins. Synthetic peptides derived from this relatively conserved sequ...

重组蛋白

Aminopeptidase A Protein, Human, Recombinant (His)
Cat.No: TMPY-00644
Species: Human
Expression System: Baculovirus Insect Cells
HIV-1 (group N, strain 06CM-U14296) gp160 (gp120 subunit) Protein (His)
Cat.No: TMPY-01558
Species: HIV
Expression System: HEK293 Cells
HIV-1 (group M, subtype A, isolate 92RW020) gp160 (gp120 subunit) Protein (His)
Cat.No: TMPY-00302
Species: HIV
Expression System: HEK293 Cells
HIV-1 gp120 Protein (His)
Cat.No: TMPJ-01313
Species: HIV
Expression System: HEK293 Cells
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