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Search Results for " glycopeptide "

20

抑制剂 & 化合物

5

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T2692	A40926 Dalbavancin Impurity,达巴霉素杂质	Antibacterial	Microbiology/Virology
	A40926 (Dalbavancin Impurity) 是Dalbavancin 的前体，是一种糖肽抗生素。它抑制革兰氏阳性细菌，对淋病奈瑟氏球菌非常有效。
T64549	Sialylglycopeptide
	Sialylglycopeptide 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64549，CAS号为 189035-43-6。
T0967	Teicoplanin Antibiotic MDL-507,MDL-507,替考拉宁,Teichomycin	Antibacterial; Antibiotic	Microbiology/Virology
	Teicoplanin (MDL-507) 是一种半合成的糖肽抗生素, 可用于由革兰氏阳性菌引起的严重感染的相关研究。
T2691	Oritavancin diphosphate 奥利万星二磷酸盐,LY333328 diphosphate	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Oritavancin diphosphate (LY333328 diphosphate) 是一种新型半合成的糖肽抗生素, 可研究革兰氏阳性菌感染。
T8507	MAC-545496	Antibacterial	Microbiology/Virology
	MAC-545496 是一种抗毒剂，可逆转耐甲氧西林的菌株中的 β-内酰胺耐药性。它是糖肽抗性相关蛋白 R 的纳摩尔抑制剂，对全长 GraR 蛋白具有很强的结合亲和力。
TP1166	ZINC77292789 Fmoc-Thr[GalNAc(Ac)3-α-D]-OH,Fmoc-Thr(Ac₃AcNH-α-Gal)-OH	Others	Others
	ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) 是制备基于三聚体 MUC1 免疫显性基序抗原的候选抗癌疫苗的起始材料，可制备含有 βGalNAc-Thr 作为 Tn 抗原异构体的合成 MUC1 糖肽，可诱导针对肿瘤细胞的抗体产生。
T71445	Bleomycin Free Base
	Bleomycin Free Base is a complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2. It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors.
T27008	Chloroorienticin A A-82846B,A82846B,A 82846B
	Chloroorienticin A is an antibiotic in the class of glycopeptide.
T25812	Mideplanin Mdl62873,Mdl 62873,Mdl-62873
	Mideplanin is a glycopeptide antibiotic.
T70020	Vancomycin monohydrochloride
	Vancomycin monohydrochloride is an amphoteric glycopeptide antibiotic that inhibits bacterial cell wall synthesis by binding to peptidoglycan.
T41038	Sephadex G 50
	Sephadex G 50 is a gel filtration medium commonly utilized in gel permeation chromatography for effective fractionation of glycopeptide mixtures.
T26256	Teicoplanin aglycone TD-A3
	Teicoplanin aglycone is an antibacterial glycopeptide antibiotic used in the prophylaxis and treatment of serious infections caused by Gram-positive bacteria, including Enterococcus faecalis and methicillin-resistant Staphylococcus aureus.
T32777	Lipid II binder 5107930 Compound 5107930
	Lipid II binder 5107930 is a lipid II binder which causes specific upregulation of the vancomycin-resistance associated gene vraX, which is implicated in the cell wall stress stimulon that confers glycopeptide resistance.
T73721	Phleomycin D1
	Phleomycin D1 (PLM D1)为Bleomycin/Phleomycin家族内的一种糖肽类抗生素，作用机制是通过结合DNA并切割之，从而引发细胞死亡。
T37740	N-Demethylvancomycin (hydrochloride)
	N-Demethylvancomycin is a glycopeptide antibiotic that has been found inNocardia orientalis.1It is active against several strains ofS. aureusandS. epidermidisin vitroandin vivo.2Formulations containing N-demethylvancomycin have been used in the treatment of bacterial infections. 1.Boeck, L.D., Mertz, F.P., Wolter, R.K., et al.N-demethylvancomycin, a novel antibiotic produced by a strain of Nocardia orientalis. Taxonomy and fermentationJ. Antibiot. (Tokyo)37(5)446-453(1984) 2.Hunt, A.H., Marconi,...
T74657	Balhimycin
	Balhimycin为一种源自Amycolatopsis sp.发酵产物的糖肽类抗生素，其展现出针对葡萄球菌和厌氧菌的显著抗菌效果。
T38178	Ristocetin A (sulfate) Ristomycin III
	Ristocetin A, a glycopeptide related to vancomycin, is an antibiotic produced by the microorganism Nocardia lurida[1]. Ristocetin A is currently in clinical use to treat bacterial infections [1]. Ristocetin A is an antibiotic which can be used to treat staphylococcal infections. The side effects of ristocetin A include thrombocytopenia and platelet agglutination. Ristocetin A has been used in two assays: the ristocetin cofactor assay and the ristocetin-induced platelet aggregation assay. These t...
T37881	Oritavancin(LY-333328)
	Oritavancin is a novel semisynthetic glycopeptide antibiotics. On August 6, 2014, the FDA approved oritavancin for treatment of skin infections. Oritavancin possesses potent and rapid bactericidal activity in vitro against a broad spectrum of both resistant and susceptible Gram-positive bacteria, including Staphylococcus aureus, MRSA, enterococci, and streptococci.
T75256	Cefilavancin
	Cefilavancin (TD-1792) 为有效的多价糖肽-头孢类异二聚体 antibiotic，针对革兰氏阳性 bacteria 显示良好抗性。该化合物在皮肤感染的研究中得到应用。
T38314	Parvodicin Complex
	Parvodicin complex is a mixture of closely related lipophilic glycopeptides originally isolated from A. parvosata. The parvodicin complex has activity against Gram-positive bacteria (MICs = 0.8-12.5 μg/ml) including methicillin-resistant strains of S. aureus (MRSA), S. hemolyticus, and E. faecalis (MICs = 0.1-25 μg/ml). Glycopeptide antibiotics act by preventing cell wall synthesis by binding and sequestering a cell wall precursor with a D-alanine-containing peptide.

化合物

Cat.No: T2692

Synonym: Dalbavancin Impurity,达巴霉素杂质

Target: Antibacterial

Sialylglycopeptide

Cat.No: T64549

Cat.No: T0967

Synonym: Antibiotic MDL-507,MDL-507,替考拉宁,Teichomycin

Target: Antibacterial, Antibiotic

Oritavancin diphosphate

Cat.No: T2691

Synonym: 奥利万星二磷酸盐,LY333328 diphosphate

Target: Others, Antibacterial, Antibiotic

Cat.No: T8507

Target: Antibacterial

Cat.No: TP1166

Synonym: Fmoc-Thr[GalNAc(Ac)3-α-D]-OH,Fmoc-Thr(Ac₃AcNH-α-Gal)-OH

Target: Others

Bleomycin Free Base

Cat.No: T71445

Chloroorienticin A

Cat.No: T27008

Synonym: A-82846B,A82846B,A 82846B

Cat.No: T25812

Synonym: Mdl62873,Mdl 62873,Mdl-62873

Vancomycin monohydrochloride

Cat.No: T70020

Cat.No: T41038

Teicoplanin aglycone

Cat.No: T26256

Synonym: TD-A3

Lipid II binder 5107930

Cat.No: T32777

Synonym: Compound 5107930

Cat.No: T73721

N-Demethylvancomycin (hydrochloride)

Cat.No: T37740

Cat.No: T74657

Ristocetin A (sulfate)

Cat.No: T38178

Synonym: Ristomycin III

Oritavancin(LY-333328)

Cat.No: T37881

Cat.No: T75256

Parvodicin Complex

Cat.No: T38314

Cat. No.	Product Name	Target	Signaling Pathways
T21498	Phleomycin	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Phleomycin 是在链霉菌中发现的，引起 DNA 切割的抗癌糖肽抗生素之一。它类似于博来霉素，它结合并插入 DNA 以破坏双螺旋的完整性。
T6116	Bleomycin Sulfate Blenoxane,硫酸博来霉素,硫酸博莱霉素,NSC125066	DNA/RNA Synthesis; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Bleomycin Sulfate (Blenoxane) 是一种糖肽抗生素，一种 DNA 合成抑制剂。Bleomycin Sulfate 可以引起 DNA 链断裂而不引起 RNA 链断裂。Bleomycin Sulfate 具有抗肿瘤活性。
T0971	Dirithromycin Dirithromycinum,地红霉素,ASE 136,LY237216,Diritromicina,Dirithromycine	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Dirithromycin (LY237216) 是一种红霉素衍生物，是一种具有口服活性的半合成大环内酯类抗生素。它用于治疗许多不同类型的细菌感染。
T8641	Vancomycin	Antibacterial; Antibiotic; Autophagy	Autophagy; Microbiology/Virology
	Vancomycin 是一种糖肽类抗生素，可以通过改变细胞膜的渗透性并选择性地抑制核糖核酸的合成以发挥抗菌活性。Vancomycin 可以用于治疗所有抗生素均无效的严重感染。
T75508	Bleomycin A5
	Bleomycin A5 (Pingyangmycin)，一种具有口服活性的糖肽类抗生素，既是抗肿瘤剂、细胞凋亡诱导剂，又是细菌代谢产物。

天然产物

Cat.No: T21498

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Bleomycin Sulfate

Cat.No: T6116

Synonym: Blenoxane,硫酸博来霉素,硫酸博莱霉素,NSC125066

Target: DNA/RNA Synthesis, Antibiotic

Cat.No: T0971

Synonym: Dirithromycinum,地红霉素,ASE 136,LY237216,Diritromicina,Dirithromycine

Target: ribosome, Antibacterial, Antibiotic

Cat.No: T8641

Target: Antibacterial, Antibiotic, Autophagy

Cat.No: T75508

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