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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6804 |
Chetomin
Chaetomin,NSC289491,BRN0077366 |
Apoptosis; HSP; HIF | Angiogenesis; Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism |
Chetomin (BRN0077366) 是球毛壳菌的活性成分,是一种无毒的非小细胞肺癌干细胞靶向分子。它是一种热休克蛋白90/缺氧诱导因子1α 途径的抑制剂。 | |||
T78602 | Chaetoglobosin C | ||
Chaetoglobosin C (Compound 4),源自真菌Chaetomium globosum KMITL-N0802,为一种蒽醌-色酮类化合物,具备抗结核分枝杆菌的活性。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN6717 |
chaetoglobosin Vb
|
Others | Others |
chaetoglobosin Vb 是一种从内生球藻中分离出来的新型细胞松弛素生物碱。 | |||
T75477 | Epicoccone B | ||
Epicoccone B 首次报道于C.globosum,具有清除 DPPH 自由基的能力,IC50值为10.8 μM,并具有有效的 α-葡萄糖苷酶抑制作用,IC50值为 27.3 μM。具有抗HIV 活性。 | |||
T75453 | 11-epi-Chaetomugilin I | ||
11-epi-Chaetomugilin I 是一种在Chaetomium globosum 中发现的代谢物。11-epi-Chaetomugilin I 对小鼠 P388 白血病细胞系、人类 HL-60 白血病细胞系、小鼠 L1210 白血病细胞系和人类 KB 表皮样癌细胞系具有显著的细胞毒性活性。 | |||
T38086 |
Neohydroxyaspergillic Acid
|
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Neohydroxyaspergillic acid is a fungal metabolite produced by A. sclerotiorum that has antibiotic and antifungal activities. It inhibits the growth of P. aeruginosa, M. smegmatis, S. aureus, E. coli, K. pneumoniae, B. mycoides, and B. subtilis bacteria (MICs = 125-500 μg/ml). Neohydroxyaspergillic acid also inhibits the growth of G. convolute, S. consortiale, P. blakesleeanus, C. globosum, and T. mentagrophytes (MICs = 175-700 μg/ml) but not A. niger, P. notatum, M. verrucaria, or S. cerevisiae ... | |||
T35752 |
Xanthoquinodin A1
Xanthoquinodin A1 |
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Xanthoquinodin A1 is a fungal metabolite that has been found inHumicolaand has diverse biological activities.1,2It inhibitsE. tenellaschizont formation in BHK-21 cells with a minimum effective concentration (MEC) value of 0.02 μg/ml.1Xanthoquinodin A1 is active againstB. subtilis,M. luteus,S. aureus,A. laidlawii, andB. fragilisin a disc assay when used at a concentration of 1 mg/ml. It is also active againstB. cereus(MIC = 0.44 μM).2Xanthoquinodin A1 is cytotoxic to KB, MCF-7, and NCI H187 cance... |