10
4
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1497 |
Liranaftate
Piritetrate,利拉萘酯,M-732 |
Antifungal | Microbiology/Virology |
Liranaftate (Piritetrate) 是一种具有抗真菌活性的硫代氨基甲酸酯和角鲨烯环氧酶抑制剂,可研究皮肤癣菌。 | |||
T1543 |
Naftifine hydrochloride
Naftifungin,盐酸萘替芬,Naftifine HCl,Naftin,Exoderil |
Hedgehog/Smoothened; Antibiotic; Antifungal | GPCR/G Protein; Microbiology/Virology; Stem Cells |
Naftifine hydrochloride (Naftifine HCl) 是一种抗生素。它具有抗真菌活性,对皮肤真菌、曲霉、Sporothrix schenckii、假丝酵母属的酵母有抑制作用。 | |||
T16033 |
ME1111
|
Others; Antifungal | Microbiology/Virology; Others |
ME1111 是毛癣菌琥珀酸脱氢酶的抑制剂,也是一种抗真菌剂,对皮癣菌具有活性。ME1111 能很好地穿透人体指甲,可用于甲癣研究。 | |||
T25982 |
Pramiconazole
R-126638,R126638,R 126638,Azoline |
Antifungal | Microbiology/Virology |
Pramiconazole (R126638) 是一种可口服的抗真菌化合物。Pramiconazole 是治疗皮肤癣菌和皮肤酵母菌感染的候选化合物,可用于治疗脂溢性皮炎。 | |||
T7026L |
Kukoamine B mesylate
|
Antioxidant | oxidation-reduction |
Kukoamine B mesylate 是从地骨皮中提取得到的新型阳离子生物碱,具有抗氧化活性,抑制 Kupffer 和 RAW 264。7 细胞中的 LPS 内化,可用于研究急性炎症和糖尿病。 | |||
T1438 |
Butoconazole nitrate
RS 35887,硝酸布康唑 |
Estrogen/progestogen Receptor; Antifungal | Endocrinology/Hormones; Microbiology/Virology |
Butoconazole nitrate (RS 35887) 是一种咪唑类抗真菌药物,可治疗由白色念珠菌引起的阴道感染。它可通过抑制类固醇合成起到抗菌作用。 | |||
T28476 |
Pyrroxamycin
LL-F42248-alpha,Dioxapyrrolomycin,AL-R2081 |
||
Pyrroxamycin is a new antibiotic. Pyrroxamycin was isolated from the culture broth of Streptomyces sp. S46506. Pyrroxamycin is active against Gram-positive bacteria and dermatophytes. | |||
T68998 |
Parconazole Free Base
|
||
Parconazole Free Base is used in veterinary as an oral fungicide with a broad-spectrum activity against dermatophytes, yeasts, and others fungi. This compound does not have any antibacterial effect. The mechanism of action involves inhibition of the fungal cytochrome P450 dependent 14alpha-dimethylation of lanosterol to ergosterol. | |||
T35857 |
Actinopyrone A
|
||
Actinopyrone A is a pyrone isolated from S. pactum with diverse biological activities. It has selective and potent antimicrobial activity against H. pylori (MIC = 0.1 ng/mL) with no activity against other Gram-negative bacteria including E. coli, K. pneumoniae, P. aeruginosa, and B. fragilis. Actinopyrone A also mildly inhibits growth of Gram-positive bacteria and dermatophytes with MIC values ranging from <6.25 to 25 μg/mL. Intravenous administration of actinopyrone A (30 μg/kg) increases coron... | |||
T27300 |
Olorofim
Olorofim,F901318,F-901318 |
||
Olorofim 是一种新型的选择性抗真菌化合物,对烟曲霉DHODH 具有抑制作用(IC50:44 nM),对人类DHODH 几乎没有抑制作用(>100 uM)。Olorofim 对青霉菌属、皮炎杆菌属、镰刀菌属等各种致病性丝状和二形真菌有很好的疗效。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8167 |
medicagenic acid
Castanogenin,苜蓿酸 |
Antibacterial | Microbiology/Virology |
Medicagenic acid (Castanogenin) 是从Herniaria glabra L 的根中分离出来的药源酸,对几种植物病原体和人类皮肤癣菌有抑菌作用。 | |||
T1411 |
Terbinafine hydrochloride
KWD 2019,盐酸特比萘芬,Terbinafine HCl,TDT 067 hydrochloride |
Antibacterial; Antibiotic; Antifungal | Microbiology/Virology |
Terbinafine hydrochloride (KWD 2019) 具有抗真菌感染活性。它是念珠菌属的角鲨烯环氧化酶的非竞争性抑制剂,Ki 值为 30 nM。它还对某些革兰氏阳性和革兰氏阴性细菌具有抗菌活性。 | |||
TN4811 |
Plumieride
|
||
Plumieride has plant growth inhibiting properties, it shows strong fungitoxicity against some dermatophytes causing dermatomycosis to animals and human beings. Plumieride also has antioxidant , and immunomodulatory activities. | |||
T69369 |
Cladosporin
|
||
Cladosporin 是一种真菌代谢物,在 Cladosporium cladosporioid 的菌丝体中产生。含浓度 75 μg/mL Cladosporin 的琼脂培养基可完全抑制多种皮肤癣菌的生长。 |