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6

抑制剂 & 化合物

2

天然产物

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Cat. No. Product Name Target Signaling Pathways
T6798 Tretazicar

5-Aziridino-2,4-dinitrobenzamide,CB1954,NSC 115829

DNA Alkylator/Crosslinker; DNA Alkylation DNA Damage/DNA Repair
Tretazicar (NSC-115829) 是一种抗肿瘤前药,由 NAD(P)H 醌氧化还原酶 2 激活。它在酶促活化后生成细胞毒性双功能烷基剂,可以形成 DNA-DNA 链间交联。
T7466 5-Bromocytosine

Others Others
5-Bromocytosine 可用于在厌氧和需氧条件下合成交联产物。
T29819 Alagebrium bromide

ALT-711,ALT 711,ALT711

Alagebrium is a advanced glycation endproducts (AGE) cross-link breaker.
T73932 Fructosyl-lysine dihydrochloride

Fructosyl-lysine (Fructoselysine) dihydrochloride 为通过美拉德反应由葡萄糖与赖氨酸反应生成的amadori glycation产物。该化合物是葡萄糖烷的前体,其中葡萄糖烷为一种赖氨酸-精氨酸蛋白交联物,常用作糖尿病检测的生物标志物。
T36894 5-Bromouridine

5-Bromouridine is a brominated analog of the nucleoside uridine .1It can be incorporated into RNA and subsequently detected by antibodies against bromodeoxyuridine .25-Bromouridine decreases the viability of HL-60 and MOLT-4 cells (LC50s = 10 and 20 μM, respectively). It induces apoptosis and halts the cell cycle at the S phase in HL-60 cells. It is photoreactive, and UV irradiation has been used to cross-link RNA containing 5-bromouridine to proteins in the study of of RNA-protein interactions....
T76142 Laccase

Laccase(Denilite IIS) 是一种多铜氧化酶(MCOs),广泛存在于微生物、植物和真菌中,能催化多种酚类化合物的一个电子的氧化。Laccase 可以促进单木质素的氧化偶联在木质素的形成中及生物降解中起着重要作用,也具有交联食品聚合物的潜力。

化合物

Tretazicar
Cat.No: T6798
Synonym: 5-Aziridino-2,4-dinitrobenzamide,CB1954,NSC 115829
Target: DNA Alkylator/Crosslinker, DNA Alkylation
5-Bromocytosine
Cat.No: T7466
Synonym:
Target: Others
Alagebrium bromide
Cat.No: T29819
Synonym: ALT-711,ALT 711,ALT711
Target:
Fructosyl-lysine dihydrochloride
Cat.No: T73932
Synonym:
Target:
5-Bromouridine
Cat.No: T36894
Synonym:
Target:
Laccase
Cat.No: T76142
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T4918 DL-Glyceraldehyde

Glyceric aldehyde,DL-甘油醛晶体

Reductase Endocrinology/Hormones; Metabolism
DL-Glyceraldehyde (Glyceric aldehyde) 是由酶甘油醛脱氢酶的作用产生的,该酶使用 NADP 作为辅因子将甘油转化为甘油醛。它是一种高活性化合物,可以修饰和交联蛋白质。
T15350 Fructosyl-lysine

Fructoselysine,果糖-赖氨酸

Others Others
Fructosyl-lysine is the precursor to glucosepane. Fructosyl-lysine is a lysine–arginine protein cross-link that can be an indicator in diabetes detection. Fructosyl-lysine is an amadori glycation product from the reaction of glucose and lysine by the Maillard reaction.

天然产物

DL-Glyceraldehyde
Cat.No: T4918
Synonym: Glyceric aldehyde,DL-甘油醛晶体
Target: Reductase
Fructosyl-lysine
Cat.No: T15350
Synonym: Fructoselysine,果糖-赖氨酸
Target: Others
TargetMol Loading
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