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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T5189	Omadacycline PTK 0796,Amadacycline	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Omadacycline (Amadacycline) 是一种具有口服活性的氨基甲基环素抗菌剂，是四环素类抗生素。它与 30S 核糖体亚基结合，抑制细菌蛋白质合成。它可用于研究急性细菌性皮肤和皮肤结构感染，感染性肺炎和尿路感染。
T0331	Moxifloxacin hydrochloride 盐酸莫西沙星,莫西沙星盐酸盐,BAY-128039,Moxifloxacin HCl,BAY12-8039 HCl	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Moxifloxacin hydrochloride (BAY12-8039 HCl) 是一种口服有效的 8-甲氧基喹诺酮类抗菌药物，可研究感染性肺炎，急性细菌性鼻窦炎和慢性支气管炎的急性细菌性加重。
T10987	Decarboxy Moxifloxacin	Others	Others
	Decarboxy Moxifloxacin 是一种莫西沙星的脱羧化合物。Moxifloxacin 是一种能够口服的 8-甲氧基喹诺酮类抗菌药物，可用于急性细菌性鼻窦炎，慢性支气管炎的急性细菌性加重和感染性肺炎。
T11836	Lefamulin acetate BC-3781 acetate,醋酸来法莫林	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Lefamulin acetate (BC-3781 acetate) 是具有口服活性的抗生素。它是用于人体细菌感染的全身研究的半合成截短侧耳素。它与 50S 细菌核糖体的肽基转移酶peptidyl transferase 中心结合抑制蛋白质合成，并阻止了转移RNA 与肽转移的结合。
T38586	Grepafloxacin dl-Grepafloxacin,OPC-17116
	Grepafloxacin (OPC-17116) is a fluoroquinolone antibiotic that is administered orally. It possesses strong efficacy against community-acquired respiratory pathogens, notably Streptococcus pneumonia. Grepafloxacin exhibits excellent tissue penetration and demonstrates a promising pharmacodynamic profile.
T28997	TP-271 TP271
	TP-271, a tetracyclines antibiotic, is used potentially for the treatment of community-acquired bacterial pneumonia (CABP).
T75274	Cefetamet
	Cefetamet 是一种头孢类抗生素。Cefetamet 具有研究上、下社区获得性呼吸道感染的潜力。
T23622	Acorafloxacin HCl JNJ-32729463,JNJ-Q2 hydrochloride,Acorafloxacin hydrochloride,JNJ 32729463,JNJ-Q2 HCl
	Acorafloxacin is a broad-spectrum fluoroquinolone antibacterial drug being developed for the treatment of acute bacterial skin and skin structure infections and community-acquired pneumonia.
T10420	Avarofloxacin JNJ-Q2	Others	Others
	Avarofloxacin (JNJ-Q2) is a broad-spectrum fluoroquinolone antibacterial drug being developed for the treatment of acute bacterial skin and community-acquired pneumonia and skin structure infections.
T70642	Lanopepden camsylate
	Lanopepden, also known as GSK-1322322 or GSK-322, is a potent and selective peptide deformylase inhibitor with good in vitro activity against bacteria associated with community-acquired pneumonia and skin infections. GSK1322322 had bactericidal activity against S. pneumoniae, H. influenzae, S. pyogenes, and S. aureus, demonstrating a ≥ 3-log(10) decrease in the number of CFU/ml at 4× MIC within 24 h in 29 of the 33 strains tested. GSK1322322 represents a valuable alternative therapy for the trea...
T71266	Omadacycline HCl
	Omadacycline, also known as PTK 0796 and Amadacyclin, is a novel first-in-class aminomethylcycline with potent activity against important skin and pneumonia pathogens, including community-acquired methicillin-resistant Staphylococcus aureus (MRSA), β-hemolytic streptococci, penicillin-resistant Streptococcus pneumoniae, Haemophilus influenzae, and Legionella. Omadacycline is active against strains expressing the two main forms of tetracycline resistance (efflux and ribosomal protection). The pri...
T74821	Nemonoxacin
	Nemonoxacin (TG-873870) 是一种口服有效的广谱抗生素，对多种葡萄球菌、链球菌、肠球菌、淋病奈瑟菌和流感嗜血杆菌显示出强效的抑制活性。适用于研究细菌感染和社区获得性肺炎。
T4543	Telithromycin HMR3647,泰利霉素,Ketek,RU66647	Antibacterial; Antibiotic	Microbiology/Virology
	Telithromycin (HMR3647) 是一种社区获得性肺炎抗生素。
T74144	Zifanocycline
	Zifanocycline (KBP-7072) 为半合成第三代氨甲基环素类抗生素，通过抑制细菌核糖体功能而发挥作用。它对革兰氏阳性菌和革兰氏阴性菌[包括多重耐药病原体]显示出广泛的体外抗菌活性。适用于口服和注射形式，Zifanocycline 主要用于研究治疗急性细菌性皮肤及其结构感染、社区获得性细菌性肺炎以及复杂腹腔感染。
T74591	Ceftaroline fosamil (hydrate)(acetate)
	Ceftaroline fosamil hydrate acetate 是一种高效的头孢菌素类抗生素(antibiotic)，对多种病原体有广谱活性，特别是针对革兰氏阳性病原体，如耐甲氧西林金黄色葡萄球菌(MRSA)和耐多药肺炎链球菌，以及常见的革兰氏阴性微生物。此外，Ceftaroline fosamil hydrate acetate 在治疗复杂皮肤及皮肤结构感染(cSSSIs)和社区获得性肺炎(CABP)方面表现出显著的抗感染活性。
T80731	Zifanocycline TFA KBP-7072 TFA
	Zifanocycline TFA (KBP-7072) 是一种半合成的氨基糖苷类抗生素，具有口服活性并能抑制细菌核糖体功能。它对广泛的革兰氏阳性菌和阴性菌示出了体外抗菌活性，包括多种耐药病原体。Zifanocycline TFA 适用于急性细菌性皮肤及皮肤结构感染、社区获得性细菌性肺炎和复杂的腹腔感染的研究。

化合物

Cat.No: T5189

Synonym: PTK 0796,Amadacycline

Target: ribosome, Antibacterial, Antibiotic

Moxifloxacin hydrochloride

Cat.No: T0331

Synonym: 盐酸莫西沙星,莫西沙星盐酸盐,BAY-128039,Moxifloxacin HCl,BAY12-8039 HCl

Target: Topoisomerase, Antibacterial, Antibiotic

Decarboxy Moxifloxacin

Cat.No: T10987

Target: Others

Lefamulin acetate

Cat.No: T11836

Synonym: BC-3781 acetate,醋酸来法莫林

Target: ribosome, Antibacterial, Antibiotic

Cat.No: T38586

Synonym: dl-Grepafloxacin,OPC-17116

Cat.No: T28997

Synonym: TP271

Cat.No: T75274

Acorafloxacin HCl

Cat.No: T23622

Synonym: JNJ-32729463,JNJ-Q2 hydrochloride,Acorafloxacin hydrochloride,JNJ 32729463,JNJ-Q2 HCl

Cat.No: T10420

Synonym: JNJ-Q2

Target: Others

Lanopepden camsylate

Cat.No: T70642

Omadacycline HCl

Cat.No: T71266

Cat.No: T74821

Cat.No: T4543

Synonym: HMR3647,泰利霉素,Ketek,RU66647

Target: Antibacterial, Antibiotic

Cat.No: T74144

Ceftaroline fosamil (hydrate)(acetate)

Cat.No: T74591

Zifanocycline TFA

Cat.No: T80731

Synonym: KBP-7072 TFA

Cat. No.	Product Name	Target	Signaling Pathways
T5041	Faropenem sodium 法罗培南,法罗培南钠	Antibacterial; Antibiotic	Microbiology/Virology
	Faropenem sodium 是一种口服生物可利用的青霉烯类抗生素，能有效杀灭结核分枝杆菌，治疗结核病和社区获得性肺炎。

天然产物

Faropenem sodium

Cat.No: T5041

Synonym: 法罗培南,法罗培南钠

Target: Antibacterial, Antibiotic

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