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38

抑制剂 & 化合物

4

天然产物

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Cat. No. Product Name Target Signaling Pathways
T61147 Chitin synthase inhibitor 4

Antibiotic Microbiology/Virology
Chitin synthase inhibitor 4 是一种具有抗菌活性的几丁质合成酶(CHS)抑制剂。Chitin synthase inhibitor 4 是一种基于CHS 的化合物,是一种候选的杀菌剂。
T63077 Chitin synthase inhibitor 12

Chitin synthase inhibitor 12 是一种几丁质合酶 (CHS) 抑制剂,具有优异的 CHS 抑制作用 (IC50: 0.16 mM)。Chitin synthase inhibitor 12 也是一种广谱抗真菌剂,对耐药真菌变体(如 C. albicans、C. neoformans)具有抗性。Chitin synthase inhibitor 12 能够用于研究侵袭性真菌感染 (IFIs)。
T61188 Chitin synthase inhibitor 2

Chitin synthase inhibitor 2 (compound 2b) is a highly potent inhibitor of chitin synthase, with an IC50 value of 0.09 mM and a K i value of 0.12 mM. This compound exhibits antimicrobial activities in vitro and demonstrates synergistic or additive effects when combined with fluconazole or polyoxin B [1].
T62739 Chitin synthase inhibitor 9

Chitin synthase inhibitor 9 是一种几丁质合成酶 (chitin synthase, CHS) 抑制剂,表现出广谱抗真菌效果。Chitin synthase inhibitor 9 能够用于进行真菌感染相关研究。
T78886 Chitin synthase inhibitor 14

Chitin synthase inhibitor 14 (compound 4n),一种CHS抑制剂,展现出优异的抗真菌活性和对耐药真菌变异的有效抗性。
T74956 Chitin synthase inhibitor 10

Chitin synthase inhibitor 10为一种高效的几丁质合酶(CHS)抑制剂,具有0.11 mM的IC50,表现出显著的CHS抑制活性。作为抗真菌剂,该化合物对包括C. albicans和C. neoformans在内的耐药真菌变体有效,适合用于侵袭性真菌感染(IFI)研究。
T62738 Chitin synthase inhibitor 6

Chitin synthase inhibitor 6 (compound 9b) 是一种 chitin synthase (CHS) 的有效抑制剂 (IC50: 0.21 mM)。Chitin synthase inhibitor 6 对耐药真菌表现出广谱抗真菌效果,能够用于研究真菌感染。
T62246 Chitin synthase inhibitor 8

Chitin synthase inhibitor 8 是一种 chitin synthase (CHS) 抑制剂,具有广谱抗真菌作用,能够用于真菌感染相关研究。
T63353 Chitin synthase inhibitor 11

Chitin synthase inhibitor 11 是一种高效的几丁质合酶 (CHS) 抑制剂,能够明显抑制 CHS 的活性 (IC50: 0.10 mM),具有广谱体外抑菌作用。Chitin synthase inhibitor 11 能够用于研究侵袭性真菌感染 (IFIs)。
T62068 Chitin synthase inhibitor 1

Chitin synthase inhibitor 1 是有效的、选择性的几丁质合酶 (CHS) 抑制剂,IC50值为0.12 mM。Chitin synthase inhibitor 1 强效抑制耐药真菌变体。
T63392 Chitin synthase inhibitor 5

Chitin synthase inhibitor 5 是一种几丁质合成酶的抑制剂 (IC50: 0.14 mM)。Chitin synthase inhibitor 5 表现出广谱的真菌抗活性,能够较好的抑制白色念珠菌、黄曲霉、烟毒念珠菌和新生念珠菌,能够用于研究真菌。
T62475 Chitin synthase inhibitor 7

Chitin synthase inhibitor 7 (compound 9c) 是一种 chitin synthase (CHS) 的有效抑制剂 (IC50: 0.37 nM)。Chitin synthase inhibitor 7 对耐药真菌具有广谱抗真菌作用。Chitin synthase inhibitor 7 能够用于研究真菌感染。
T79481 Chitin synthase inhibitor 13

Chitin synthase inhibitor 13 (compound 12g) 为非竞争性几丁质合酶抑制剂,其IC50为106.7 μM,展现出广谱抗真菌活性。
T61398 Chitin synthase inhibitor 3

Chitin synthase inhibitor 3 (compound 2d) 是一种高效的chitin synthase抑制剂,具有0.16 mM的IC50值,并对candida albicans显示出1 μg/mL的MIC,表现出抗真菌活性。
T5637 Triflumuron

Others Others
Triflumuron 是一种杀虫剂,属于所谓的昆虫生长调节剂。它抑制昆虫幼虫合成甲壳素,导致死亡。
T5639 lufenuron

Fluphenacur,虱螨脲

Parasite Microbiology/Virology
Lufenuron (Fluphenacur) 和几丁质合成抑制剂,可抑制节肢动物的蜕皮,控制蚤和鱼虱。
T7088 Diflubenzuron

Dimilin,氟脲杀,Difubenzuron,Larvakil,Difluron

P450 Metabolism
Diflubenzuron (Larvakil) 是杀虫剂 Dimilin 的有效成分,具有杀幼虫和杀卵作用。
T3496 Buprofezin

噻嗪酮,NNI 750,Applaud,Buprofezine

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
Buprofezin (Applaud) 是一种杀虫剂,通过抑制几丁质合成起作用,在体外还可以剂量依赖性地增加活性氧的产生。
T40656 Chlorobenzuron

Others Others
Chlorobenzuron 是一种有效的几丁质合成酶抑制剂,具有杀虫的活性,可以抑制幼虫发育和蛹化的作用。
T8814 Nikkomycin Z

尼柯霉素Z,Nikkomycin Z from Streptomyces tendae,尼柯霉素 Z

Others; Antibiotic; Antifungal Microbiology/Virology; Others
Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) 是一种选择性竞争性几丁质合成抑制剂。它是一种核苷肽,可作为几丁质合酶底物 UDP-N-乙酰氨基葡萄糖的竞争性类似物,具有抗真菌作用。
T10788 Chitinase-IN-2

Others Others
Chitinase-IN-2 is an insect chitinase and N- acetyl hexosaminidase inhibitor and pesticide.
T125643 7-Methylsudachitin

7-Methylsudachitin 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125643,CAS号为 16520-78-8。
T62122 Chitinase-IN-5

Chitinase-IN-5 (8i) 是一种几丁质酶OfChi-h 的有效抑制剂 (IC50: 0.051 μM),具有良好的杀虫作用。Chitinase-IN-5 能够用于研究绿色害虫防治和管理。
T73612 Chitinase

Chitinase 具有部分具有溶菌酶活性,广泛存在于细菌、真菌、动物和一些植物中。Chitinase 属于糖基水解酶家族大豆几丁质酶催化壳寡糖水解。
T23882 Chitinovorin B

Chitinovorin B is a beta-lactam antibiotic.
T62069 Chitinase-IN-4

Chitinase-IN-4 (compound 8f) 是一种有效的、选择性的 OfChi-h 抑制剂,其 IC50 值为 0.1 μM,具有良好的杀虫作用。
T10788L Chitinase-IN-2 hydrochloride

Chitinase-IN-2 hydrochloride (1579991-63-1 free base)

Others Others
Chitinase-IN-2 hydrochloride 是昆虫几丁质酶抑制剂和N-乙酰氨基己糖苷酶抑制剂。
T10787 Chitinase-IN-1

Others Others
Chitinase-IN-1 is an insect chitinase and N- acetyl hexosaminidase inhibitor and pesticide.
T4055 Etoxazole

Others Others
Etoxazole 是一种杀螨剂/杀虫剂,通过抑制几丁质生物合成来控制螨虫。用作农药检测的标准。
T5117 Hexaflumuron

Others Others
Hexazinone 是一种三嗪家族的非选择性除草剂。它能够同光系统 II 电子传递链的 D-1 醌蛋白结合,抑制光合作用的发生。
T19735 Flucycloxuron

氟螨脲,(E)-flucycloxuron,Andalin

Others Others
Flucycloxuron ((E)-flucycloxuron) 是一种甲壳素合成抑制剂,用作杀虫剂。在昆虫模型中,该抑制剂已被证明会影响几种生殖事件,例如产卵前的持续时间。
T35837 Flufenoxuron

Flufenoxuron, a benzoylurea insecticide, acts as a chitin synthesis inhibitor. Its usage involves inhibiting chitin synthesis, reducing molting, and impeding egg hatching, resulting in the prevention of insect development[1].
T28436 Polyoxin B

Polyoxin-B

Polyoxin B is a nucleoside antibiotics composed of heterocyclic moieties containing nitrogen. Polyoxin B inhibits the biosynthesis of chitin.
T39822 Polyoxin D

Polyoxorim

Polyoxin D (Polyoxorim), a polyoxin antibiotic fungicide, effectively inhibits chitin synthetase.
T20231 Cellufluor

Phorwite AR,Paper White BP,Kayaphor FB,Tinopal 5BMS

Cellufluor is a fluorochrome. It has an affinity for chitin and cellulose.
T37850 Chitobiose Octaacetate

Chitobiose is a dimer of β-1,4 linked glucosamine units derived from chitin, which, in turn, is a long chain polymer of N-acetylglucosamine that is a primary component of fungal cell walls and arthropod exoskeletons. Chitobiose octaacetate is a form of chitobiose containing eight acetate groups. It is formed by the acetolysis of chitin. Chitobiose octaacetate can be used for the synthesis of chitobiose oxazoline and other chitin precursors.
T21154 Chlorfluazuron

IKI 7899,AI3-29785,CCRIS 2680,CGA 112913,Atabron

Chlorfluazuron, a chitin synthesis inhibitor, is commonly used as an insect growth regulator for controlling the major insect pests in crops.
T37574 4-Nitrophenyl-N-acetyl-α-D-galactosaminide

N-acetyl-D-galactosaminidase catalyzes the cleavage of N-acetylglucosamine (GlcNAc), the monomeric unit of the polymer chitin. 4-Nitrophenyl-N-acetyl-α-D-galactosaminide can be used as a chromogenic substrate for N-acetyl-D-galactosaminidase, generating a yellow solution upon cleavage.

化合物

Chitin synthase inhibitor 4
Cat.No: T61147
Synonym:
Target: Antibiotic
Chitin synthase inhibitor 12
Cat.No: T63077
Synonym:
Target:
Chitin synthase inhibitor 2
Cat.No: T61188
Synonym:
Target:
Chitin synthase inhibitor 9
Cat.No: T62739
Synonym:
Target:
Chitin synthase inhibitor 14
Cat.No: T78886
Synonym:
Target:
Chitin synthase inhibitor 10
Cat.No: T74956
Synonym:
Target:
Chitin synthase inhibitor 6
Cat.No: T62738
Synonym:
Target:
Chitin synthase inhibitor 8
Cat.No: T62246
Synonym:
Target:
Chitin synthase inhibitor 11
Cat.No: T63353
Synonym:
Target:
Chitin synthase inhibitor 1
Cat.No: T62068
Synonym:
Target:
Chitin synthase inhibitor 5
Cat.No: T63392
Synonym:
Target:
Chitin synthase inhibitor 7
Cat.No: T62475
Synonym:
Target:
Chitin synthase inhibitor 13
Cat.No: T79481
Synonym:
Target:
Chitin synthase inhibitor 3
Cat.No: T61398
Synonym:
Target:
Triflumuron
Cat.No: T5637
Synonym:
Target: Others
lufenuron
Cat.No: T5639
Synonym: Fluphenacur,虱螨脲
Target: Parasite
Diflubenzuron
Cat.No: T7088
Synonym: Dimilin,氟脲杀,Difubenzuron,Larvakil,Difluron
Target: P450
Buprofezin
Cat.No: T3496
Synonym: 噻嗪酮,NNI 750,Applaud,Buprofezine
Target: Reactive Oxygen Species
Chlorobenzuron
Cat.No: T40656
Synonym:
Target: Others
Nikkomycin Z
Cat.No: T8814
Synonym: 尼柯霉素Z,Nikkomycin Z from Streptomyces tendae,尼柯霉素 Z
Target: Others, Antibiotic, Antifungal
Chitinase-IN-2
Cat.No: T10788
Synonym:
Target: Others
7-Methylsudachitin
Cat.No: T125643
Synonym:
Target:
Chitinase-IN-5
Cat.No: T62122
Synonym:
Target:
Chitinase
Cat.No: T73612
Synonym:
Target:
Chitinovorin B
Cat.No: T23882
Synonym:
Target:
Chitinase-IN-4
Cat.No: T62069
Synonym:
Target:
Chitinase-IN-2 hydrochloride
Cat.No: T10788L
Synonym: Chitinase-IN-2 hydrochloride (1579991-63-1 free base)
Target: Others
Chitinase-IN-1
Cat.No: T10787
Synonym:
Target: Others
Etoxazole
Cat.No: T4055
Synonym:
Target: Others
Hexaflumuron
Cat.No: T5117
Synonym:
Target: Others
Flucycloxuron
Cat.No: T19735
Synonym: 氟螨脲,(E)-flucycloxuron,Andalin
Target: Others
Flufenoxuron
Cat.No: T35837
Synonym:
Target:
Polyoxin B
Cat.No: T28436
Synonym: Polyoxin-B
Target:
Polyoxin D
Cat.No: T39822
Synonym: Polyoxorim
Target:
Cellufluor
Cat.No: T20231
Synonym: Phorwite AR,Paper White BP,Kayaphor FB,Tinopal 5BMS
Target:
Chitobiose Octaacetate
Cat.No: T37850
Synonym:
Target:
Chlorfluazuron
Cat.No: T21154
Synonym: IKI 7899,AI3-29785,CCRIS 2680,CGA 112913,Atabron
Target:
4-Nitrophenyl-N-acetyl-α-D-galactosaminide
Cat.No: T37574
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T22291 Chitin

Chitin (From shrimp and crab shells)

Others Others
Chitin 是一种大型的结构多糖,存在于真菌的细胞壁、昆虫的外骨骼以及鱼类和无脊椎动物的某些坚硬结构中。
T1715 Chitosan (MW 150000)

壳聚糖,Chitosan,Poly(D-glucosamine),Deacetylated chitin

Antibacterial; Antifungal Microbiology/Virology
Chitosan (MW 150000) (Deacetylated chitin) 是衍生自几丁质的聚阳离子线性多糖。它无毒,具有低致敏性,生物相容性和可生物降解性。它还具有抗肿瘤,抗细菌,抗真菌和抗氧化活性。
T38555 Chitotetraose tetrahydrochloride

Chitotetraose tetrahydrochloride is a short-chain chitin oligomer derived from arbuscular mycorrhizal (AM) fungi. This compound effectively activates the conserved symbiosis signaling pathway (CSSP) in actinorhizal plant species.
T40436 N,N'-Diacetylchitobiose

N,N'-Diacetylchitobiose, a dimer of β(1,4) linked N-acetyl-D glucosamine, is derived from the hydrolysis of chitin. This compound serves as an alternative carbon source for E. coli.

天然产物

Chitin
Cat.No: T22291
Synonym: Chitin (From shrimp and crab shells)
Target: Others
Chitosan (MW 150000)
Cat.No: T1715
Synonym: 壳聚糖,Chitosan,Poly(D-glucosamine),Deacetylated chitin
Target: Antibacterial, Antifungal
Chitotetraose tetrahydrochloride
Cat.No: T38555
Synonym:
Target:
N,N'-Diacetylchitobiose
Cat.No: T40436
Synonym:
Target:
TargetMol Loading
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