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Cat. No. Product Name Target Signaling Pathways
TP1158 Copper tripeptide

[N2-(N-甘氨酰-L-组氨酰)-L-赖氨酸]铜,GHK-Cu

Others; Endogenous Metabolite Metabolism; Others
Copper tripeptide (GHK-Cu) 是天然存在的三肽,首先从人血浆中分离,但也能够在唾液和尿液中发现。它能够提高成纤维细胞中胶原蛋白,弹性蛋白,蛋白多糖和糖胺聚糖中信使 RNA 的产生。在伤口愈合期间,它能够通过蛋白水解从现有的细胞外蛋白质中除去,并且用作炎性和内皮细胞的化学引诱物。它是皮肤再生中多种细胞途径的天然调节剂。
T11648 INCB 3284

Others Others
INCB 3284, a potent and selective human CCR2 antagonist with an oral bioavailability, is utilized in the study of acute liver failure. It effectively inhibits the binding of monocyte chemoattractant protein-1 (MCP-1) to hCCR2, demonstrating an IC50 of 3.7 nM.
T16850 SB-265610

GSK-CXCR2

CXCR Autophagy; GPCR/G Protein; Immunology/Inflammation
SB-265610 (GSK-CXCR2) 是竞争性非肽变构CXCR2选择性拮抗剂,可阻断大鼠 CINC-1 诱导的钙动员和中性粒细胞趋化性,IC50分别为 3.7 和 70 nM。
T14565 BI-671800

AP-761,Cmpd A

GPR; Prostaglandin Receptor Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation
BI-671800 (AP-761) 是高特异性的前列腺素 D2 受体拮抗剂,对哮喘有研究潜力,对人和小鼠 CRTH2 转染细胞中 PGD2 结合 CRTH2 的 IC50值分别为 4.5 和 3.7 nM。
TP1164 N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA

For-Nle-Leu-Phe-Nle-Tyr-Lys-OH (TFA)

Others Others
N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH (TFA)) (71901-21-8 free base) 是一种甲酰肽受体 (FPR) 激动剂 。人类中性粒细胞。放射性碘化分子具有充分的生物活性。
T22789 FPR A14

Others Others
FPR A14 是甲酰肽受体 (FPR) 的激动剂,可诱导细胞分化。
T31937 Glorin

Glorin is a chemoattractant mediating cell aggregation in the slime mold Polysphondylium violaceum.
T68216 Sanguiin h 11

Sanguiin h 11 is a compound purified from the plant Sanguisorba officinalis and has proven to be a potent inhibitor of chemoattractant-dependent and independent neutrophil movement.
T80131 C5a Anaphylatoxin (human)

Complement System Immunology/Inflammation
C5a Anaphylatoxin (human)为促炎多肽及白细胞化学引诱剂,主要应用于炎症与免疫领域研究,例如过敏性哮喘。
T11647 INCB 3284 dimesylate

Others Others
INCB 3284 dimesylate is a selective and orally bioavailable human CCR2 antagonist, inhibiting monocyte chemoattractant protein-1 binding to hCCR2 (IC50: 3.7 nM). It can be used in the research of acute liver failure.
T71913 Bourgeonal

Bourgeonal is an agonist of human testicular olfactory receptor hOR17-4. It increases cytosolic calcium levels in human spermatozoa, acts as a chemoattractant, and increases swimming speed in sperm chemotaxis assays in a concentration-dependent manner.
T37798 Petromyzonol

Petromyzonol is a tetrahydroxy stearol which serves as the primary spawning pheromone in adult sea lamprey. It is produced in the bile of sea lamprey larvae from the bile acid precursor allocholic acid. While the adult sea lamprey is relatively insensitive to petromyzonol itself, the C-24 sulfate ester (petromyzonol sulfate) is a pheromone and a spawning chemoattractant which can be detected at very low concentrations by lamprey olfactory chemoreceptors. Petromyzonol, petromyzonol sulfate, and a...
T78038 H-Pro-Gly-Pro-OH

H-Pro-Gly-Pro-OH 是胶原蛋白衍生物,在生物医学领域中以其嗜中性粒细胞趋化性而被研究。该分子诱使中性粒细胞在特定部位集聚,并促进局部细胞修复过程。此外,H-Pro-Gly-Pro-OH 还能激活缺血后脑部的神经营养因子及其受体的基因表达。
T80258 WRW4-OH

WRW4-OH 是一种抑制 WKYMVm(一种 FPRL1 激动剂)与其受体结合的生物活性肽。FPRL1,作为典型的趋化受体,在外周血液和大脑的吞噬细胞中有表达,其激活过程与宿主的防御机制及神经退行性疾病相关炎症反应紧密相连。
T36130 22(S)-hydroxy Cholesterol

22(S)-hydroxy Cholesterol,22β-hydroxy Cholesterol

22(S)-hydroxy Cholesterol is a synthetic oxysterol and a modulator of the liver X receptor (LXR). [1] t prevents monocyte chemoattractant protein 1 (MCP-1) expression induced by the LXR agonist GW 3965 in primary hepatocytes and downregulates mRNA expression of the LXR target genes CD36, ACSL1, and SCD-1 in human myotubes. It decreases triacylglycerol and diacylglycerol synthesis from labeled palmitate and acetate, respectively, in human myoblasts by 50% when used at a concentration of 10 uM. 22...
T38309 LL-37 amide (trifluoroacetate salt)

LL-37 is a cationic and α-helical antimicrobial peptide expressed in human bone marrow, testis, granulocytes, and gingival epithelium and is upregulated in psoriatic lesions. It inhibits growth of Gram-positive E. coli D21 and Gram-negative B. megatarium in a concentration-dependent manner and LL-37 expression is induced in A549 epithelial cells, alveolar macrophages, neutrophils, and monocyte-derived macrophages following M. tuberculosis infection. LL-37 binds sheep erythrocytes coated with S. ...

化合物

Copper tripeptide
Cat.No: TP1158
Synonym: [N2-(N-甘氨酰-L-组氨酰)-L-赖氨酸]铜,GHK-Cu
Target: Others, Endogenous Metabolite
INCB 3284
Cat.No: T11648
Synonym:
Target: Others
SB-265610
Cat.No: T16850
Synonym: GSK-CXCR2
Target: CXCR
BI-671800
Cat.No: T14565
Synonym: AP-761,Cmpd A
Target: GPR, Prostaglandin Receptor
N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA
Cat.No: TP1164
Synonym: For-Nle-Leu-Phe-Nle-Tyr-Lys-OH (TFA)
Target: Others
FPR A14
Cat.No: T22789
Synonym:
Target: Others
Glorin
Cat.No: T31937
Synonym:
Target:
Sanguiin h 11
Cat.No: T68216
Synonym:
Target:
C5a Anaphylatoxin (human)
Cat.No: T80131
Synonym:
Target: Complement System
INCB 3284 dimesylate
Cat.No: T11647
Synonym:
Target: Others
Bourgeonal
Cat.No: T71913
Synonym:
Target:
Petromyzonol
Cat.No: T37798
Synonym:
Target:
H-Pro-Gly-Pro-OH
Cat.No: T78038
Synonym:
Target:
WRW4-OH
Cat.No: T80258
Synonym:
Target:
22(S)-hydroxy Cholesterol
Cat.No: T36130
Synonym: 22(S)-hydroxy Cholesterol,22β-hydroxy Cholesterol
Target:
LL-37 amide (trifluoroacetate salt)
Cat.No: T38309
Synonym:
Target:
TargetMol Loading
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