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Search Results for " c-erbb2 "

Targets Recommended: EGFR

4

抑制剂 & 化合物

11

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T21954	EGFR/ErbB-2/ErbB-4 inhibitor-2 EGFR/ErbB2 Inhibitor	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR/ErbB-2/ErbB-4 inhibitor-2 (EGFR/ErbB2 Inhibitor) 是EGFR 和ErbB 的抑制剂，对EGFR、ErbB2 和 ErbB4 的IC50分别为 0.017、0.08 和 1.91 μM。
T4014	CP-724714 CP724714,CP 724714	Apoptosis; EGFR	Angiogenesis; Apoptosis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	CP-724714 (CP724714) 是一种高效、选择性口服活性的 ErbB2 (HER2)酪氨酸激酶抑制剂，IC50为 10 nM。它能抑制完整细胞中 ErbB2 受体的自磷酸化，具有抗肿瘤活性。它对 EGFR 激酶有明显的选择性，IC50值为6400 nM。
T2116	AEE788 NVP-AEE 788	Apoptosis; EGFR; c-Fms; FLT; Bcr-Abl	Angiogenesis; Apoptosis; Cytoskeletal Signaling; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	AEE788 (NVP-AEE 788)是EGFR 和ErbB2的抑制剂，IC50值分别为2和6 nM。它已用于研究癌症、多形性胶质母细胞瘤以及脑和中枢神经系统肿瘤治疗的试验。
T6734	WZ8040	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	WZ8040 是一种新型突变选择性不可逆 EGFRT790M 抑制剂，可抑制EGFR 磷酸化。它对突变型EGFR 的活性是野生型EGFR 的100倍以上。

化合物

EGFR/ErbB-2/ErbB-4 inhibitor-2

Cat.No: T21954

Synonym: EGFR/ErbB2 Inhibitor

Target: EGFR

Cat.No: T4014

Synonym: CP724714,CP 724714

Target: Apoptosis, EGFR

Cat.No: T2116

Synonym: NVP-AEE 788

Target: Apoptosis, EGFR, c-Fms, FLT, Bcr-Abl

Cat.No: T6734

Target: EGFR

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02469	HER2/ERBB2 Protein, Mouse, Recombinant (hFc) EGFR2,c-erbB2,l11Jus8,	Mouse	HEK293 Cells
	HER2/ERBB2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.7 kDa and the accession number is P70424.
TMPY-02314	HER2/ERBB2 Protein, Mouse, Recombinant (His) HER2,c-erbB2,erb-b2<...	Mouse	HEK293 Cells
	HER2/ERBB2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is P70424.
TMPJ-00791	HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His) p185erbB2,Epidermal growth factor...	Rat	E. coli
	ERBB2 belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. It contains a protein kinase domain. ERBB2 is widely expressed in epithelial cells, and amplification and/or overexpression of ErbB2 has been reported associated with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate and ovarian cancers. Rat ERBB2 is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. ErbB...
TMPJ-00778	HER2/ERBB2 Protein, Human, Recombinant (His) TKR1,Metastatic lymph node gene 19 protein,ERBB...	Human	HEK293 Cells
	HER2/ERBB2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 90-120 KDa and the accession number is P04626.
TMPK-00430	HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi), Biotinylated MLN19,HERV7Q,HERVW,MLN 19,TKR1,herstatin,ENVW,EGFR2...	Human	HEK293 Cells
	HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.5 kDa and the accession number is P04626-1.
TMPJ-00777	HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc) TKR1,Proto-oncogene Neu,EGFR2,Tyrosine kin...	Human	HEK293 Cells
	HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 120-145 KDa and the accession number is P04626.
TMPK-00429	HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi) HERV7Q,HER-2,HER2,NGL,EGFR2,ENVW,...	Human	HEK293 Cells
	HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.5 kDa and the accession number is P04626-1.
TMPJ-00776	HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated Tyrosine kinase-type cell surface rec<...	Human	HEK293 Cells
	HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 120-140 KDa and the accession number is P04626.
TMPK-01450	HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated KRAS1,MHC,K-RAS4B,KRAS,CFC2	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01456	HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi) KRAS2,NS,MHC,C-K-RAS,KRAS1,K-RAS<...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01451	HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi) NS3,K-RAS4A,K-Ras 2,NS,KRAS1,RASK2,MHC...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.

重组蛋白

HER2/ERBB2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02469

Species: Mouse

Expression System: HEK293 Cells

HER2/ERBB2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02314

Species: Mouse

Expression System: HEK293 Cells

HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His)

Cat.No: TMPJ-00791

Species: Rat

Expression System: E. coli

HER2/ERBB2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00778

Species: Human

Expression System: HEK293 Cells

HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00430

Species: Human

Expression System: HEK293 Cells

HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc)

Cat.No: TMPJ-00777

Species: Human

Expression System: HEK293 Cells

HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00429

Species: Human

Expression System: HEK293 Cells

HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPJ-00776

Species: Human

Expression System: HEK293 Cells

HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01450

Species: Human

Expression System: HEK293 Cells

HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01456

Species: Human

Expression System: HEK293 Cells

HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01451

Species: Human

Expression System: HEK293 Cells

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