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Targets Recommended: P450 Adrenergic Receptor PPAR

3

抑制剂 & 化合物

9

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T1415 Gemfibrozil

吉非罗齐,CI-719,Jezil,Decrelip,Lopid

P450; Adrenergic Receptor; PPAR DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
Gemfibrozil (CI-719) 是一种PPAR-α激活剂,可作为降脂药。它也是P450非选择性抑制剂,对 CYP2C9、2C19、2C8 和 1A2 的Ki 值分别为 5.8、24、69 和 82 μM。
T1406 Amantadine hydrochloride

盐酸金刚烷胺,1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride

Dopamine Receptor; Influenza Virus GPCR/G Protein; Microbiology/Virology; Neuroscience
Amantadine hydrochloride (CI-719) 是一种抗病毒药物,用于预防或对症治疗甲型流感和帕金森病。它阻断质子流通过 M2 离子通道,从而阻止病毒 RNA 释放到感染细胞的细胞质中。
T71306 Gemfibrozil-d6

Gemfibrozil-d6 is intended for use as an internal standard for the quantification of gemfibrozil by GC- or LC-MS. Gemfibrozil is a peroxisome proliferator-activated reporter α and PPARγ agonist. In vivo, gemfibrozil reduces serum total cholesterol, triglyceride, and LDL levels in a rat model of high-cholesterol diet-induced hyperlipidemia. Gemfibrozil reduces atherosclerotic plaque area, superoxide production, and expression of the genes encoding the NF-κB subunit p65 and chemokine (C-C) motif l...

化合物

Gemfibrozil
Cat.No: T1415
Synonym: 吉非罗齐,CI-719,Jezil,Decrelip,Lopid
Target: P450, Adrenergic Receptor, PPAR
Amantadine hydrochloride
Cat.No: T1406
Synonym: 盐酸金刚烷胺,1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride
Target: Dopamine Receptor, Influenza Virus
Gemfibrozil-d6
Cat.No: T71306
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-02899 Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (His)

Apoa-1,2-Sep,42248,1-Sep,apolipoprotei...

Mouse HEK293 Cells
Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.2 kDa and the accession number is Q00623.
TMPJ-00158 Apolipoprotein A-I/APOA1 Protein, Human, Recombinant

Apolipoprotein A-I,APOA1...

Human E. coli
Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various biological processes, such as Cholesterol metabolism, Lipid metabolism and transport, Steroid metabolism. APOA1 promotes cholesterol efflux from tissues to the liver and thus helps to clear cholesterol from arteries. Defects in this gene resulted in HDL deficiencies, including T...
TMPY-02553 Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (aa 1-264, hFc)

apolipoprotein A-I,1-Sep,Apoa...

Mouse HEK293 Cells
Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (aa 1-264, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 55.8 kDa and the accession number is Q00623.
TMPY-06955 Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (hFc)

Alp-1,1-Sep,Ltw-1,Lvtw-1,Apoa-1,42248,apoli

Mouse HEK293 Cells
Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.68 kDa and the accession number is Q00623.
TMPH-00224 APOA1 Protein, Bovine, Recombinant (E. coli, His)

APOA1,Apolipoprotein A-I...

Bovine E. coli
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. APOA1 Protein, Bovine, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.6 kDa and the accession number is P15497.
TMPH-00225 APOA1 Protein, Bovine, Recombinant (His)

Apolipoprotein A-I,APOA1...

Bovine P. pastoris (Yeast)
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. APOA1 Protein, Bovine, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 29.5 kDa and the accession number is P15497.
TMPK-00768 ANXA1 Protein, Human, Recombinant (His)

Annexin A1,Calpactin II,...

Human E. coli
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activities in an apoA-I- or ANXA1-dependent manner. The latter activity occurs by mediating the efflux of ANXA1, which plays a critical role in anti-inflammatory effects, cholesterol transport, exosome and microparticle secretion, and apoptotic cell clearance. ANXA1 Protein, Human, Re...
TMPK-01291 ANXA1 Protein, Cynomolgus, Recombinant (His)

Lipocortin I,Calpactin-2...

Cynomolgus E. coli
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activities in an apoA-I- or ANXA1-dependent manner. The latter activity occurs by mediating the efflux of ANXA1, which plays a critical role in anti-inflammatory effects, cholesterol transport, exosome and microparticle secretion, and apoptotic cell clearance. ANXA1 Protein, Cynomolgu...
TMPK-00799 ANXA1 Protein, Mouse, Recombinant (His)

Calpactin-2,LPC1,Annexin-1,Annexi...

Mouse E. coli
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activities in an apoA-I- or ANXA1-dependent manner. The latter activity occurs by mediating the efflux of ANXA1, which plays a critical role in anti-inflammatory effects, cholesterol transport, exosome and microparticle secretion, and apoptotic cell clearance. ANXA1 Protein, Mouse, Re...

重组蛋白

Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02899
Species: Mouse
Expression System: HEK293 Cells
Apolipoprotein A-I/APOA1 Protein, Human, Recombinant
Cat.No: TMPJ-00158
Species: Human
Expression System: E. coli
Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (aa 1-264, hFc)
Cat.No: TMPY-02553
Species: Mouse
Expression System: HEK293 Cells
Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-06955
Species: Mouse
Expression System: HEK293 Cells
APOA1 Protein, Bovine, Recombinant (E. coli, His)
Cat.No: TMPH-00224
Species: Bovine
Expression System: E. coli
APOA1 Protein, Bovine, Recombinant (His)
Cat.No: TMPH-00225
Species: Bovine
Expression System: P. pastoris (Yeast)
ANXA1 Protein, Human, Recombinant (His)
Cat.No: TMPK-00768
Species: Human
Expression System: E. coli
ANXA1 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01291
Species: Cynomolgus
Expression System: E. coli
ANXA1 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00799
Species: Mouse
Expression System: E. coli
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