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抑制剂 & 化合物

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T21529	(S)-Mephenytoin	Others	Others
	(S)-Mephenytoin 是一种抗惊厥剂。(S)-Mephenytoin 作为细胞色素 P450 (CYP) 同种型 CYP2C19 的底物，可用于分析细胞色素 P450 代谢。
TP1188L	Cortistatin 14, human, rat acetate	Somatostatin	GPCR/G Protein
	Cortistatin 14, human, rat acetate 是一种与 somatostatin-14 结构相似的神经肽，具有抗惊厥、神经保护作用和显着的抗炎特性。 Cortistatin 14, human, rat acetate 通过与生长抑素受体结合并发挥其功能。
TP1570L	Cortistatin-14 acetate Cortistatin-14 acetate(186901-48-4 Free base)	Somatostatin	GPCR/G Protein
	Cortistatin-14 acetate 是一种与生长抑素-14结构相似的神经肽，通过生长抑素受体 (sst1-sst5) 结合并发挥作用。Cortistatin-14 acetate 具有抗惊厥、神经保护作用和显著的抗炎作用。
T25764	LY 81067 Lilly-81067,LY81067,Lilly81067,Lilly 81067,LY-81067
	LY 81067是一种新型抗惊厥化合物，可有效预防戊四唑和苦防己毒素诱导的小鼠惊厥。它通过结合到苦防己素结合位点或其附近来发挥其抗惊厥作用。
T12772	(RS)-PPG	Others	Others
	(RS)-PPG is a potent and selective group III mGluRs agonist(EC50s of 5.2 μM, 4.7 μM, 185 μM, and 0.2 μM for hmGluR4a, hmGluR6, hmGluR7b, and hmGluR8a, respectively),with neuroprotective and anticonvulsive activity.
T38601	GYKI-47261 dihydrochloride
	GYKI-47261 dihydrochloride is a selective AMPA receptor antagonist, administered orally, and exhibits competitive activity with an IC 50 of 2.5 μM. It displays a wide range of anticonvulsive effects and demonstrates neuroprotective properties. Additionally, GYKI-47261 dihydrochloride is a potent inducer of CYP2E1.
T76034	Cortistatin-14 TFA
	Cortistatin-14 (TFA) 是一种神经肽，其结构与生长抑素-14相似，通过与生长抑素受体(sst1-sst5)结合来发挥效果。它具备抗惊厥、神经保护和显著抗炎作用。
T8775	Lisuride maleate R-(+)-LISURIDE HYDROGEN MALEATE
	Lisuride maleate is an agonist of Dopamine receptor and anti-Parkinson's agent. Displays high affinity for D2, D3 and D4 receptors along with 5-HT1A. Exhibits some 5-HT2B receptor antagonist properties. Decreases prolactin release; reduces inflammatory me

化合物

Cortistatin 14, human, rat acetate

Cat.No: TP1188L

Synonym:

Target: Somatostatin

Cortistatin-14 acetate

Cat.No: TP1570L

Synonym: Cortistatin-14 acetate(186901-48-4 Free base)

Target: Somatostatin

LY 81067

Cat.No: T25764

Synonym: Lilly-81067,LY81067,Lilly81067,Lilly 81067,LY-81067

GYKI-47261 dihydrochloride

Synonym: R-(+)-LISURIDE HYDROGEN MALEATE

Target:

Cat. No.	Product Name	Target	Signaling Pathways
T2S1814	p-Hydroxybenzaldehyde 4-Formylphenol,4-羟基苯甲醛;对羟基苯甲醛,4-hydroxybenzaldehyde,对羟基苯甲醛,p-Oxybenzaldehyde	Transaminase; GABA Receptor; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism; Neuroscience
	p-Hydroxybenzaldehyde (p-Oxybenzaldehyde) 是从天麻中提取的一种天然产物，对 GABA 转氨酶有抑制作用，有助于抗癫痫和抗惊厥活性。
T2860	Vanillyl Alcohol 4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,香兰醇,Vanillin alcohol,Vanillic alcohol	Apoptosis; Others	Apoptosis; Others
	Vanillyl Alcohol (3-Methoxy-4-hydroxybenzyl alcohol) 是一种酚类醇，具有抗血管生成、抗惊厥、抗炎、抗氧化、神经保护和抗伤害活性。它由香兰素衍生而来，在食品和饮料中用作调味剂。
T80777	Withaphysalin R
	Withaphysalin R (化合物 5)，一种可从茄科植物中提取的睡茄内酯 (Withanolide)，具有麦角固醇框架的甾体内酯。其活性包括细胞毒性、免疫抑制、抗肿瘤、抗炎、抗惊厥及抗氧化等显著生物活性。