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Cat. No.	Product Name	Target	Signaling Pathways
T2684	JNJ-1661010 JNJ1661010,Takeda-25,JNJ 1661010	FAAH	Metabolism; Neuroscience
	JNJ-1661010 (Takeda-25) 是一种有效的、选择性的、可以穿透血脑屏障的脂肪酸酰胺水解酶 (FAAH) 抑制剂，对大鼠和人 FAAH 的 IC50分别为 34 和 33 nM，可用于缓解疼痛的研究。
T5424	Etosalamide 依托柳胺,Ethosalamide	Others	Others
	Etosalamide (Ethosalamide) 是一种解热缓解疼痛的试剂。它具有抗炎作用，可用于研究过敏性疾病。
T0778	Phenacetin 非那西丁,Acetophenetidin	COX	Immunology/Inflammation; Neuroscience
	Phenacetin (Acetophenetidin) 是一种非阿片类解热化合物，可用于缓解疼痛的研究。它是一种选择性的COX-3抑制剂，能作为人肝微粒体和大鼠体内 CYP1A2 的探针。
T8634	8-Bromotheophylline Bromotheophylline,8-溴茶碱	Others	Others
	8-Bromotheophylline (Bromotheophylline) 是 Pamabrom 的活性部分，用于 Oxazolo[2,3-f]purinediones 的合成。Oxazolo[2,3-f]purinediones 可用于腺苷 A1和 A2A 受体上的亲和力评估。
T71995	Decanoyl chloride
	Decanoyl Chloride is used in the synthesis of an effective metalloproteinase inhibitor. Also acts as a reagent in the synthesis of reversible α-ketoheterocycle inhibitors of fatty acid amide hydrolase as potnetial analgesics.
T69422	Flupirtine HCl
	Flupirtine HCl is the salt form of Flupirtine, also known as W-2964, an aminopyridine that functions as a centrally acting non-opioid analgesic. It first became available in Europe in 1984, and is sold mainly under the names Katadolon, Trancolong, Awegal, Efiret, Trancopal Dolo, and Metanor. Like nefopam, it is unique among analgesics in that it is a non-opioid, non-NSAID, non-steroidal centrally acting analgesic. Flupirtine is a selective neuronal potassium channel opener that also has NMDA re...
T71955	C3001a
	C3001a is a selective activator for TREK, against other two-pore domain K+(K2P) channels. C3001a binds to the cryptic binding site formed by P1 and TM4 in TREK-1. C3001a targets TREK channels in the peripheral nervous system to reduce the excitability of nociceptive neurons. In neuropathic pain, C3001a alleviated spontaneous pain and cold hyperalgesia. In a mouse model of acute pancreatitis, C3001a alleviated mechanical allodynia and inflammation. C3001a represents a lead compound which could a...
T80446	ω-Conotoxin FVIA	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	ω-Conotoxin FVIA为N型钙离子通道(Cav2.2)的抑制剂，具有减轻尾神经损伤大鼠模型所诱导的机械性和热性异常疼痛的作用。该化合物在开发高效且低副作用止痛药物的研究中具有潜在应用价值。
T37199	Bilaid C
	Bilaid C is a tetrapeptide μ-opioid receptor agonist (Ki= 210 nM in HEK293 cell membranes expressing the human receptor) that has been found inPenicillium.1It inhibits forskolin-induced cAMP accumulation by 77% in HEK293 cells expressing the human μ-opioid receptor when used at a concentration of 10 μM. Bilaid C induces inward rectifying potassium channel (Kir) currents in rat locus coeruleus slices that endogenously express high levels of the μ-opioid receptor (EC50= 4.2 μM). 1.Dekan, Z., Siana...