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Cat. No. Product Name Target Signaling Pathways
T13336 VTP50469

Apoptosis; Epigenetic Reader Domain; Histone Methyltransferase Apoptosis; Chromatin/Epigenetic
VTP50469 是一种高选择性和口服活性的Menin-MLL 相互作用抑制剂,具有有效的抗白血病活性,Ki 为 104 pM。
T13336L VTP50469 fumarate

Others Others
VTP50469 fumarate is a highly selective and orally active inhibitor of Menin-MLL interaction (Ki: 104 pM), and has potently anti-leukemia activity.
T69846 VTP50469 mesylate

VTP-50469 is a novel, potent, selective, orally-available MeninMLL1 inhibitor, being effectively against MLL-rearranged and NPM1c+ leukemia, selectively killing cell lines with MLLrearrangements and NPM1c+ mutations.
T69845 MX107

MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.

化合物

VTP50469
Cat.No: T13336
Synonym:
Target: Apoptosis, Epigenetic Reader Domain, Histone Methyltransferase
VTP50469 fumarate
Cat.No: T13336L
Synonym:
Target: Others
VTP50469 mesylate
Cat.No: T69846
Synonym:
Target:
MX107
Cat.No: T69845
Synonym:
Target:
TargetMol Loading
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