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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T82502 Efaprinermin alfa

OMP-336B11

Efaprinermin alfa (OMP-336B11),一种人源化单克隆抗体,靶向TNFRSF18。该化合物为GITR配体-Fc融合蛋白。

化合物

Efaprinermin alfa
Cat.No: T82502
Synonym: OMP-336B11
Target:
Cat. No. Product Name Species Expression System
TMPK-01260 GITR/TNFRSF18 Protein, Cynomolgus, Recombinant (aa 20-156, His)

TNFRSF18,GITR-D,AITR,CD357,GITR

Cynomolgus HEK293 Cells
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. GITR/TNFRSF18 Protein, Cynomolgus, Recombinant (aa 20-156, His) is expressed in HEK293 ...
TMPK-00132 GITR/TNFRSF18 Protein, Human, Recombinant (aa 26-161, His & Avi), Biotinylated

GITR-D,CD357,AITR,GITR,TNFRSF18

Human HEK293 Cells
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. GITR/TNFRSF18 Protein, Human, Recombinant (aa 26-161, His & Avi), Biotinylated is expre...
TMPK-00133 GITR/TNFRSF18 Protein, Human, Recombinant (aa 26-161, His)

GITR-D,AITR,GITR,CD357,TNFRSF18

Human HEK293 Cells
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. GITR/TNFRSF18 Protein, Human, Recombinant (aa 26-161, His) is expressed in HEK293 mamma...
TMPK-01086 GITR/TNFRSF18 Protein, Mouse, Recombinant (aa 22-153, His)

TNFRSF18,AITR,GITR-D,CD357,GITR

Mouse HEK293 Cells
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. GITR/TNFRSF18 Protein, Mouse, Recombinant (aa 22-153, His) is expressed in HEK293 mamma...
TMPY-00072 GITR/TNFRSF18 Protein, Human, Recombinant (His)

AITR,GITR-D,tumor necrosis factor receptor superfamily, memb...

Human HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is Q9Y5U5-3.
TMPJ-00110 GITR/TNFRSF18 Protein, Mouse, Recombinant (hFc & His)

Tnfrsf18,GITR-D,CD357,AITR,Tumor necrosis ...

Mouse HEK293 Cells
Tumor necrosis factor receptor superfamily member 18(Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA、isformB and isformC is single-pass type I membrane protein and isformD is a secreted protein. The protein is the receptor for TNFSF18.It seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. It mediated NF-kappa-B activation via the TRAF2/NIK pathway.It binds to TRAF1, TRAF2, and...
TMPY-05155 GITR/TNFRSF18 Protein, Cynomolgus, Recombinant (His)

tumor necrosis factor receptor superfamily, member 18

Cynomolgus HEK293 Cells
GITR/TNFRSF18 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.1 kDa and the accession number is XP_005545180.1.
TMPY-05253 GITR/TNFRSF18 Protein, Mouse, Recombinant (mFc)

AITR,tumor necrosis factor receptor superfamily, member ...

Mouse HEK293 Cells
GITR/TNFRSF18 Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 41 kDa and the accession number is O35714-1.
TMPY-03232 GITR/TNFRSF18 Protein, Rat, Recombinant (hFc)

tumor necrosis factor receptor superfamily, member 18

Rat HEK293 Cells
GITR/TNFRSF18 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 37.7 kDa and the accession number is Q5M835.
TMPY-05233 GITR/TNFRSF18 Protein, Human, Recombinant (His), Biotinylated

GITR-D,CD357,AITR,GITR,tumor necrosis factor receptor superf...

Human HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is Q9Y5U5-3.
TMPY-06017 GITR/TNFRSF18 Protein, Mouse, Recombinant (His)

Gitr,AITR,tumor necrosis factor receptor superfamily, member...

Mouse HEK293 Cells
GITR/TNFRSF18 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.5 kDa and the accession number is O35714-1.
TMPY-04265 GITR/TNFRSF18 Protein, Human, Recombinant (hFc)

GITR-D,tumor necrosis factor receptor superfamily, member

Human HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.5 kDa and the accession number is Q9Y5U5-1.
TMPY-05602 GITR/TNFRSF18 Protein, Human, Recombinant (hFc & Avi), Biotinylated

AITR,GITR,tumor necrosis factor receptor superfamily, member...

Human HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 43.1 kDa and the accession number is Q9Y5U5-3.
TMPY-06411 GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated

CD357,GITR-D,tumor necrosis factor receptor superfamily, mem...

Human HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.79 kDa and the accession number is Q9Y5U5-3.
TMPK-00053 GITR Ligand/TNFSF18 Protein, Human, Recombinant (His & Flag)

AITRL,TNFSF18,TL6,GITR Ligand,GITRL

Human HEK293 Cells
Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept. GITR Ligand/TNFSF18 Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecula...
TMPK-01064 GITR Ligand/TNFSF18 Protein, Mouse, Recombinant (hFc)

GITRL,GITR Ligand,TL6,TNFSF18,AITRL

Mouse HEK293 Cells
Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept. GITR Ligand/TNFSF18 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is ...
TMPK-00054 GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated

TL6,GITR Ligand,TNFSF18,AITRL,GITRL

Human HEK293 Cells
Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept. GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated is expressed in HEK293 mammalian cells with...
TMPJ-00432 GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His)

GITRL,TNFSF18,Activation-inducible TNF-related liga...

Cynomolgus HEK293 Cells
TNFSF18 is a single-pass type II membrane protein. It is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 cytokine binds to TNFRSF18/AITR/GITR. It regulates T-cell responses, and functions as costimulator and lower the threshold for T-cell activation and T-cell proliferation. It is Important for interactions between activated T-lymphocytes and endothelial cells and Promotes leukocyte adhesion to endothelial cells. TNFSF18 mediates activation ...

重组蛋白

GITR/TNFRSF18 Protein, Cynomolgus, Recombinant (aa 20-156, His)
Cat.No: TMPK-01260
Species: Cynomolgus
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (aa 26-161, His & Avi), Biotinylated
Cat.No: TMPK-00132
Species: Human
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (aa 26-161, His)
Cat.No: TMPK-00133
Species: Human
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Mouse, Recombinant (aa 22-153, His)
Cat.No: TMPK-01086
Species: Mouse
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His)
Cat.No: TMPY-00072
Species: Human
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Mouse, Recombinant (hFc & His)
Cat.No: TMPJ-00110
Species: Mouse
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-05155
Species: Cynomolgus
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Mouse, Recombinant (mFc)
Cat.No: TMPY-05253
Species: Mouse
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03232
Species: Rat
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05233
Species: Human
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-06017
Species: Mouse
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04265
Species: Human
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-05602
Species: Human
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06411
Species: Human
Expression System: HEK293 Cells
GITR Ligand/TNFSF18 Protein, Human, Recombinant (His & Flag)
Cat.No: TMPK-00053
Species: Human
Expression System: HEK293 Cells
GITR Ligand/TNFSF18 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-01064
Species: Mouse
Expression System: HEK293 Cells
GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
Cat.No: TMPK-00054
Species: Human
Expression System: HEK293 Cells
GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-00432
Species: Cynomolgus
Expression System: HEK293 Cells
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