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Cat. No. Product Name Target Signaling Pathways
T9845 Thrombin inhibitor 5

Thrombin inhibitor 5 (compound 385) 是一种凝血酶抑制剂,IC50范围为 0.1 μM~1 μM,可用于静脉血栓栓塞的研究。
T7496 Thrombin Receptor Activator for Peptide 5 (TRAP-5)

Thrombin Receptor Activator for Peptide

Protease-activated Receptor GPCR/G Protein
Thrombin Receptor Activator for Peptide 5 (TRAP-5) 也称为凝血因子 II 受体 (1-5) 或蛋白酶激活受体 1 (1-5),用于研究冠心病 (CHD)。
T10951 Dabigatran ethyl ester hydrochloride

N-[[2-[[[4-(氨基亚氨甲基)苯基]氨基]甲基]-1-甲基-1H-苯并咪唑-5-基]羰基]-N-(2-吡啶基)-BETA-丙氨酸乙酯盐酸盐

Others; Thrombin Others; Proteases/Proteasome
Dabigatran ethyl ester hydrochloride 是一种核糖基二氢烟酰胺脱氢酶抑制剂,IC50=0.8 μM,也是一种凝血酶的抑制剂。
T72322 R 59-022 hydrochloride

DKGI-I hydrochloride,Diacylglycerol kinase inhibitor I hydrochloride,DKGI-I hydrochloride ; Diacylglycerol kinase inhibitor I hydrochloride

5-HT Receptor; PKC Chromatin/Epigenetic; Cytoskeletal Signaling; GPCR/G Protein; Neuroscience
R 59-022 hydrochloride (DKGI-I hydrochloride) 是一种 5-HT Receptor 拮抗剂,可激活蛋白激酶 C (PKC)。R 59-022 hydrochloride 是一种 DGK 抑制剂 (IC50:2.8 µM),可抑制 OAG 磷酸化为 OAPA。R 59-022 增强血小板中凝血酶诱导的甘油二酯的产生,并抑制嗜中性粒细胞中磷脂酸的产生。
T16709 R 59-022

Diacylglycerol kinase inhibitor I,DKGI-I

Others Others
R 59-022 is a 5-HTR antagonist and activates protein kinase C (PKC). R 59-022 is a diacylglycerol kinase inhibitor (IC50=2.8 μM). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neu
T36777 Thrombin Receptor Agonist Peptide (trifluoroacetate salt)

Thrombin receptor agonist peptide (TRAP-14) is a 14-amino acid peptide agonist of the α-thrombin receptor. It induces aggregation of washed platelets as well as platelets in citrated and hirudin plasma. TRAP-14 (100 μM) increases the cytosolic calcium concentration in isolated guinea pig pulmonary smooth muscle cells 5-fold over baseline. It increases pulmonary arterial pressure in isolated guinea pig lung when used at a concentration of 1 μM, which is comparable to the effect induced by 10 nM α...
T75242 Bivalirudin TFA

Bivalirudin TFA 是20个氨基多肽,可逆地抑制凝血酶。

化合物

Thrombin inhibitor 5
Cat.No: T9845
Synonym:
Target:
Thrombin Receptor Activator for Peptide 5 (TRAP-5)
Cat.No: T7496
Synonym: Thrombin Receptor Activator for Peptide
Target: Protease-activated Receptor
Dabigatran ethyl ester hydrochloride
Cat.No: T10951
Synonym: N-[[2-[[[4-(氨基亚氨甲基)苯基]氨基]甲基]-1-甲基-1H-苯并咪唑-5-基]羰基]-N-(2-吡啶基)-BETA-丙氨酸乙酯盐酸盐
Target: Others, Thrombin
R 59-022 hydrochloride
Cat.No: T72322
Synonym: DKGI-I hydrochloride,Diacylglycerol kinase inhibitor I hydrochloride,DKGI-I hydrochloride ; Diacylglycerol kinase inhibitor I hydrochloride
Target: 5-HT Receptor, PKC
R 59-022
Cat.No: T16709
Synonym: Diacylglycerol kinase inhibitor I,DKGI-I
Target: Others
Thrombin Receptor Agonist Peptide (trifluoroacetate salt)
Cat.No: T36777
Synonym:
Target:
Bivalirudin TFA
Cat.No: T75242
Synonym:
Target:
TargetMol Loading
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