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Search Results for " tgfbr2 "

2

抑制剂 & 化合物

11

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T77189	Sudubrilimab
	Sudubrilimab (HS636) 是一种针对 PDL1的 Ig G1-kappa 单克隆抗体。Sudubrilimab 在重链的 C 末端与 TGF-β1受体 Ⅱ 胞外域 (TGFBR2-ECD) 融合，可在免疫抑制性肿瘤微环境中隔离 PD-1/PD-L1通路和 TGF-β 生物活性。
T83770	Klotho-derived Peptide 1 (56-87) (human) TFA KP1 (56-87)
	Klotho衍生肽1（KP1）(56-87)是从人类Klotho蛋白质中衍生的肽，具有扰乱TGF-β信号传导的作用。它与TGF-β受体类型1（TGFBR2）和TGF-β受体类型2（TGFBR2；Kds分别为1.41和14.6µM）结合。KP1（10 µg/ml）的预孵育抑制TGF-β在NRK-49F大鼠成纤维细胞中诱导的纤维连接蛋白和α-平滑肌肌动蛋白（α-SMA）水平的增加。在体内，KP1（每天1 mg/kg）选择性地定位于受损的肾脏，并减少血清肌酐和血尿素氮水平，这些是肾功能的标志物，同时也减少了小鼠单侧输尿管阻塞（UUO）和单侧缺血-再灌注损伤诱导的肾脏纤维化模型中的肾纤维化。

化合物

Cat.No: T77189

Klotho-derived Peptide 1 (56-87) (human) TFA

Cat.No: T83770

Synonym: KP1 (56-87)

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00335	TGFBR2 Protein, Mouse, Recombinant (His) TGFR-2,TGF-beta type II receptor,Transforming growt...	Mouse	HEK293 Cells
	TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2.
TMPK-00328	TGFBR2 Protein, Human, Recombinant (mFc & Avi) TAAD2,LDS2B,LDS2,MFS2,	Human	HEK293 Cells
	The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects activities inside the cell such as stimulation of cell growth and division. TGFBR2 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The pred...
TMPY-05157	TGFBR2 Protein, Human, Recombinant (His) LDS2B,FAA3,TAAD2,MFS2,TGFR-2<...	Human	Baculovirus Insect Cells
	TGFBR2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.8 kDa and the accession number is P37173.
TMPK-00329	TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated LDS2B,TbetaR-II,TGFβR2,LDS2,RIIC,...	Human	HEK293 Cells
	The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects activities inside the cell such as stimulation of cell growth and division. TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-mFc-Avi...
TMPJ-00333	TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) Transforming growth factor-β receptor type II,TbetaR-II,TGF-...	Mouse	HEK293 Cells
	TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-75 KDa and the accession number is Q62312.
TMPJ-00334	TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) TGF-β receptor type II,Tgfbr2,TGF-β recept...	Mouse	HEK293 Cells
	TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-65 KDa and the accession number is Q62312-2.
TMPY-05508	TGFBR2 Protein, Human, Recombinant (hFc) TGFβ-RII,TGFbeta-RII,MFS2,AAT3,transforming growth ...	Human	HEK293 Cells
	TGFBR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.2 kDa and the accession number is P37173.
TMPY-03082	TGFBR2 Protein, Rat, Recombinant (hFc) transforming growth factor, β receptor II,transforming growt...	Rat	HEK293 Cells
	TGFBR2 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43 kDa and the accession number is P38438.
TMPY-03171	TGFBR2 Protein, Rhesus, Recombinant (hFc) transforming growth factor, β receptor II,transforming growt...	Rhesus	HEK293 Cells
	TGFBR2 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.4 kDa and the accession number is H9YUL0.
TMPY-05810	TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated RIIC,TAAD2,AAT3,TGFβ-RII,FAA3,transforming growth f...	Human	HEK293 Cells
	TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 43.4 kDa and the accession number is P37173.
TMPJ-00361	Endoglin Protein, Human, Recombinant (Trx & His) CD105,END,Endoglin,ENG	Human	E. coli
	Endoglin is a single-pass type I membrane protein which restricted to endothelial cells in all tissues except bone marrow. Endoglin as major glycoprotein of vascular endothelium, it has been found on endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. Furthermore, Homodimer forms a heteromeric complex with the signaling receptors for transforming growth factor-beta: TGFBR1 and/or TGFBR2. It may have an important role in the binding of endothelial cells to integrins an...

重组蛋白

TGFBR2 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00335

Species: Mouse

Expression System: HEK293 Cells

TGFBR2 Protein, Human, Recombinant (mFc & Avi)

Cat.No: TMPK-00328

Species: Human

Expression System: HEK293 Cells

TGFBR2 Protein, Human, Recombinant (His)

Cat.No: TMPY-05157

Species: Human

Expression System: Baculovirus Insect Cells

TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated

Cat.No: TMPK-00329

Species: Human

Expression System: HEK293 Cells

TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)

Cat.No: TMPJ-00333

Species: Mouse

Expression System: HEK293 Cells

TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)

Cat.No: TMPJ-00334

Species: Mouse

Expression System: HEK293 Cells

TGFBR2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05508

Species: Human

Expression System: HEK293 Cells

TGFBR2 Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-03082

Species: Rat

Expression System: HEK293 Cells

TGFBR2 Protein, Rhesus, Recombinant (hFc)

Cat.No: TMPY-03171

Species: Rhesus

Expression System: HEK293 Cells

TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated

Cat.No: TMPY-05810

Species: Human

Expression System: HEK293 Cells

Endoglin Protein, Human, Recombinant (Trx & His)

Cat.No: TMPJ-00361

Species: Human

Expression System: E. coli

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