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Search Results for " tnfa "

6

抑制剂 & 化合物

20

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T71726	TNFalpha-IN-S10
	TNFalpha-IN-S10 is an inhibitor of TNF-α.
T20168	Aurothiomalate sodium 金硫丁二钠,Myocrisin,Myocrisine,Miochrysin,Sodium aurothiomalate,Myochrysine,gold sodium thiomalate	Others; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Others
	Aurothiomalate sodium (Miochrysin) 是一种选择性的致癌 PKCι信号传导抑制剂，可抑制肿瘤细胞增殖。它是一种硫氧还蛋白还原酶 (TrxR) 抑制剂，也是一种抗风湿剂。
T80601	Pegsunercept PEG sTNF-RI
	Pegsunercept (PEG sTNF-RI)，一种偶联有pegol结构的特异性靶向TNFA单克隆抗体。
T62959	LRH-1 modulator-1
	LRH-1 modulator-1 是一种有效的 LRH-1 (肝受体同源物 -1) 调节剂/激动剂。LRH-1 modulator-1 能够诱导抗炎细胞因子 IL-10，对炎症细胞因子 IL-1b 和 TNFa 表现出抑制作用。LRH-1 modulator-1 在肠道类器官中具有抗炎活性。
T8996	AQX-016A
	AQX-016A 是一种口服有效的 SHIP1激动剂。AQX-016A 是 Pelorol 的结构类似物，在相同摩尔浓度下，其效力是海洋天然产物 Pelorol 的 3 倍。AQX-016A 可以在体外激活重组 SHIP1酶并刺激 SHIP1活性。AQX-016A 还可抑制 PI3K 通路和 TNFa 的产生，可用于各种炎症疾病的研究。
T71510	MF-592
	MF-592 is a potent and selective antagonists of the EP4 receptor. MF-592 demonstrated good functional potency (hEP4 IC50 = 3 nM) and potent inhibition of PGE2 modulated TNFa release in LPS stimulated human whole blood (hWB) (IC50 = 78nM). In addition, it showed an excellent oral pharmacokinetic (PK) profile and in vivo efficacy in a rat chronic adjuvant-induced-arthritis model (ED50 = 0.1 mg/kg/day).. MF-592 has a desirable overall preclinical profile that suggests it is suitable for further de...

化合物

TNFalpha-IN-S10

Cat.No: T71726

Aurothiomalate sodium

Cat.No: T20168

Synonym: 金硫丁二钠,Myocrisin,Myocrisine,Miochrysin,Sodium aurothiomalate,Myochrysine,gold sodium thiomalate

Target: Others, PKC

Cat.No: T80601

Synonym: PEG sTNF-RI

LRH-1 modulator-1

Cat.No: T62959

Cat.No: T8996

Cat.No: T71510

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04146	TNF alpha Protein, Human, Recombinant (hFc) DIF,TNFA,tumor necrosis factor,TNFSF2,TNF-α,TNF-alp...	Human	HEK293 Cells
	TNF alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.8 kDa and the accession number is P01375.
TMPY-00936	TNF alpha Protein, Human, Recombinant TNFA,TNFSF2,TNF-alpha,TNF-α,DIF,肿瘤坏死因子,tumor necros...	Human	E. coli
	TNF alpha Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P01375.
TMPY-01294	TNF alpha Protein, Mouse, Recombinant TNF-α,Tnfsf1a,TNF-alpha,TNF-a,Tnfa,tumor necrosis f...	Mouse	E. coli
	TNF alpha Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.39 kDa and the accession number is P06804.
TMPJ-00779	TNF alpha Protein, Rabbit, Recombinant TNF-a,Tumor Necrosis Factor,TNF-α,TNF α,Cachectin,肿瘤坏死因子,Tum...	Rabbit	E. coli
	Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNFα is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other ...
TMPK-00583	TNF alpha Protein, Ferret, Recombinant (His) TNF-α,DIF,TNFα,TNF-alpha,TNF α,Cachectin,APC1 protein,TNF,	Ferret	E. coli
	TNF alpha Protein, Ferret, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 18.88 kDa and the accession number is A3FBF1.
TMPY-05237	TNF alpha Protein, Human, Recombinant, Biotinylated TNFSF2,DIF,TNF-α,tumor necrosis factor,肿瘤坏死因子,TNF-alpha,...	Human	E. coli
	TNF alpha Protein, Human, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P01375.
TMPY-05187	TNF alpha Protein, Mouse, Recombinant, Biotinylated Tnfa,TNFSF2,肿瘤坏死因子,Tnfsf1a,TNF-alpha,TNFal...	Mouse	E. coli
	TNF alpha Protein, Mouse, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 17.4 kDa and the accession number is P06804.
TMPK-00119	TNF alpha Protein, Cynomolgus, Recombinant (His) TNF α,TNFα,APC1 protein,TNF-alpha,TNFA,TNF-α,TN...	Cynomolgus	HEK293 Cells
	TNF alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 18.35 kDa and the accession number is P79337.
TMPK-00120	TNF alpha Protein, Human, Recombinant (His & Avi) TNFα,APC1 protein,肿瘤坏死因子,TNFSF2,TNF,TNF α,TNF-alpha,TNF-α,TN...	Human	HEK293 Cells
	TNF alpha Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 20.3 kDa and the accession number is P01375.
TMPK-00121	TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated TNF,TNF-alpha,TNFATNF,DIF,TNFalpha,TNFα,	Human	HEK293 Cells
	TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 20.3 kDa and the accession number is P01375.
TMPJ-00124	TNF alpha Protein, Human, Recombinant (aa 77-233, His) TNF-a,TNF-α,Tumor Necrosis Factor,TNFA,Tumor Necros...	Human	E. coli
	TNF alpha Protein, Human, Recombinant (aa 77-233, His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 16 KDa and the accession number is P01375.
TMPJ-00125	TNF alpha Protein, Human, Recombinant (aa 57-233, His) TNFA,TNF-α,Cachectin,肿瘤坏死因子,TNF-Alpha,TNF-a,TNF α,T...	Human	E. coli
	TNF alpha Protein, Human, Recombinant (aa 57-233, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18 KDa and the accession number is P01375.
TMPY-01697	TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (His) Tnfr-1,TNFR80,TNF-R-II,TNF-αR2,tumor necrosis factor recepto...	Mouse	HEK293 Cells
	TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is P25119.
TMPY-02535	TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc) TNFalpha-R1,TNFAR,TNF-R-I,TNF-R,TNFRp55,FP...	Mouse	HEK293 Cells
	TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.4 kDa and the accession number is P25118.
TMPY-01696	TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (hFc) TNF-αR2,TNF-R-II,Tnfr2,TNFalpha-R2,TNFBR,tumor necr...	Mouse	HEK293 Cells
	TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.3 kDa and the accession number is P25119.
TMPY-01639	TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (His) TNFalpha-R1,TNFRp55,CD120a,TNF-alphaR1,FPF,p55-R,TN...	Mouse	HEK293 Cells
	TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.8 kDa and the accession number is P25118.
TMPH-02265	TNFAIP6 Protein, Human, Recombinant (His)	Human	E. coli
	Possibly involved in cell-cell and cell-matrix interactions during inflammation and tumorigenesis. TNFAIP6 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33.1 kDa and the accession number is P98066.
TMPH-02266	TNFAIP6 Protein, Human, Recombinant (His & Myc)	Human	Baculovirus Insect Cells
	Possibly involved in cell-cell and cell-matrix interactions during inflammation and tumorigenesis.
TMPY-03416	TNFAIP8 Protein, Human, Recombinant (His) GG2-1,tumor necrosis factor, alpha-induced protein 8,SCCS2,S...	Human	E. coli
	Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8) family is a newly identified protein with vital roles in maintaining immune homeostasis. Tumor necrosis factor-alpha-inducible protein 8 (TNFAIP8) is a TNF-alpha inducible anti-apoptotic protein with multiple roles in tumor growth and survival. by the creation of cellular autophagy events, TNFAIP8 promotes cell survival and drug resistance in prostate cancer cells. TNFAIP8 regulates Hippo pathway through interacting with LATS1 to prom...
TMPK-00090	NKp30/NCR3 Protein, Human, Recombinant (His & Avi) NKp30,1C7,MALS,CD337,LY117,NCR3	Human	HEK293 Cells
	NKp30, along with NKp44 and NKp46, constitute a group of receptors termed "Natural Cytotoxicity Receptors". These receptors play a major role in triggering NK-mediated killing of most tumor cells lines.NKp30 stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature ph...

重组蛋白

TNF alpha Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04146

Species: Human

Expression System: HEK293 Cells

TNF alpha Protein, Human, Recombinant

Cat.No: TMPY-00936

Species: Human

Expression System: E. coli

TNF alpha Protein, Mouse, Recombinant

Cat.No: TMPY-01294

Species: Mouse

Expression System: E. coli

TNF alpha Protein, Rabbit, Recombinant

Cat.No: TMPJ-00779

Species: Rabbit

Expression System: E. coli

TNF alpha Protein, Ferret, Recombinant (His)

Cat.No: TMPK-00583

Species: Ferret

Expression System: E. coli

TNF alpha Protein, Human, Recombinant, Biotinylated

Cat.No: TMPY-05237

Species: Human

Expression System: E. coli

TNF alpha Protein, Mouse, Recombinant, Biotinylated

Cat.No: TMPY-05187

Species: Mouse

Expression System: E. coli

TNF alpha Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00119

Species: Cynomolgus

Expression System: HEK293 Cells

TNF alpha Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00120

Species: Human

Expression System: HEK293 Cells

TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00121

Species: Human

Expression System: HEK293 Cells

TNF alpha Protein, Human, Recombinant (aa 77-233, His)

Cat.No: TMPJ-00124

Species: Human

Expression System: E. coli

TNF alpha Protein, Human, Recombinant (aa 57-233, His)

Cat.No: TMPJ-00125

Species: Human

Expression System: E. coli

TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01697

Species: Mouse

Expression System: HEK293 Cells

TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02535

Species: Mouse

Expression System: HEK293 Cells

TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-01696

Species: Mouse

Expression System: HEK293 Cells

TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01639

Species: Mouse

Expression System: HEK293 Cells

TNFAIP6 Protein, Human, Recombinant (His)

Cat.No: TMPH-02265

Species: Human

Expression System: E. coli

TNFAIP6 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02266

Species: Human

Expression System: Baculovirus Insect Cells

TNFAIP8 Protein, Human, Recombinant (His)

Cat.No: TMPY-03416

Species: Human

Expression System: E. coli

NKp30/NCR3 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00090

Species: Human

Expression System: HEK293 Cells

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