Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1815 |
Dapivirine
R147681,达匹维林,TMC120 |
Apoptosis; HIV Protease; Reverse Transcriptase; Autophagy | Apoptosis; Autophagy; Microbiology/Virology; Proteases/Proteasome |
Dapivirine (R147681) 是一种二芳基嘧啶非核苷类逆转录酶抑制剂。 | |||
T69627 | Dapivirine HCl | ||
Dapivirine HCl is the salt form of Dapivirine, also known as TMC120, a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM. The HIV-1 replication inhibitor dapivirine (DPV) is one of the most promising drug candidates being used in topical microbicide products for prevention of HIV-1 sexual transmission. |