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Cat. No.	Product Name	Target	Signaling Pathways
T34775	TAK285-Iodo TAK-285-Iodo,TAK 285-Iodo,TAK285 derative
	TAK285-IODO, similar to TAK285 in which the trifluoro group is replaced by iodo, is a novel dual erbB protein kinase inhibitor that specifically targets human epidermal growth factor receptor (EGFR) and HER2.
T6039	TAK-285 TAK285,TAK 285	EGFR; MEK; HER; Aurora Kinase	Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; JAK/STAT signaling; MAPK; Tyrosine Kinase/Adaptors
	TAK-285 是一种新型 HER2 和 EGFR(HER1) 双重抑制剂，IC50 分别为 17 和 23 nM。它可穿过血脑屏障，有抗肿瘤活性，对 HER1/2 的选择性是 HER4 的 10 倍以上。