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Search Results for " t25 "

Targets Recommended: HSP

4

抑制剂 & 化合物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T14905	CCT251236	HSP	Cytoskeletal Signaling; Metabolism
	CCT251236 is an orally available Pirin ligand obtained from a heat shock transcription factor 1 (hsf1) phenotypic screen. It inhibits HSF1-mediated HSP72 induction (IC50: 19 nM).
T14907	CCT251545	Wnt/beta-catenin	Cytoskeletal Signaling; Stem Cells
	CCT251545 是一种有效的、具有口服活性的WNT 抑制剂，在 7dF3 细胞中对 WNT 抑制作用的IC50值为 5 nM。它是选择性化学探针，用于探索 CDK8 和 CDK19 在人类疾病中的作用。
T14906	CCT251455	Kinesin	Cytoskeletal Signaling
	CCT251455 is an inhibitor of mitotic kinase monopolar spindle 1 (MPS1; IC50: 3 nM).
T22633	CCT251545 analogue, Compound 51	Others	Others
	CCT251545 analog is a potent and selective CDK8/19 inhibitor (IC50: 5.1 nM and 5.6 nM, respectively). Mediator complex-associated kinases CDK8 and CDK19 are involved in the regulation of multiple transcription pathways. CDK8 plays as an oncogene in gastri

化合物

Cat.No: T14905

Target: HSP

Cat.No: T14907

Target: Wnt/beta-catenin

Cat.No: T14906

Target: Kinesin

CCT251545 analogue, Compound 51

Cat.No: T22633

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01473	Thy1/CD90 Protein, Mouse, Recombinant (His) CD90,Thy-1.2,Thy-1,Thy1.2,T25,Thy-1 cell surface an...	Mouse	HEK293 Cells
	Thy1/CD90 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.2 kDa and the accession number is P01831.
TMPY-02596	GLT25D2 Protein, Human, Recombinant (His) GLT25D2,RP11-498P10.2,collagen β(1-O)galactosyltran...	Human	Baculovirus Insect Cells
	Glycosyl transferase 25 domain 2 (GLT25D2) is a glucosyltransferase enzyme expressed only at low levels in the nervous system. Glycosyltransferases are enzymes that act as a catalyst for the transfer of a monosaccharide unit from an activated nucleotide sugar (also known as the "glycosyl donor") to a glycosyl acceptor molecule, usually an alcohol. Glycosyl transferases transfer glycosyl groups onto their substrate. Localization partially defines their function. Glt25D2 enzyme showed a strong gal...
TMPH-02277	PTPN11 Protein, Human, Recombinant (T253M & Q257L, His)	Human	E. coli
	Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway. Dephosphorylates GAB1, ARHGAP35 and EGFR. Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulation of its RhoA binding activity. Dephosphorylates CDC73. Dephosphorylates SOX9 on tyrosine residues, leading to inactivate SOX9 and promote ossification.

重组蛋白

Thy1/CD90 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01473

Species: Mouse

Expression System: HEK293 Cells

GLT25D2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02596

Species: Human

Expression System: Baculovirus Insect Cells

PTPN11 Protein, Human, Recombinant (T253M & Q257L, His)

Cat.No: TMPH-02277

Species: Human

Expression System: E. coli

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