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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7947 |
FT113
|
Fatty Acid Synthase | Metabolism |
FT113 是口服具有活力的脂肪酸合酶抑制剂,对全长重组人 FASN 酶的 IC50=213 nM。在 BT474 细胞中,它抑制 FASN 的特性,IC50=90 nM。它具有抗增殖作用,在体内和体外实验中,都具有抗癌作用。 | |||
T68939 |
GT11
|
||
GT-11 is an inhibitor of dihydroceramides (DHCer) desaturase activity. | |||
T79187 |
CT1113
|
||
CT1113是一种针对USP28和USP25的高效抑制剂,能够在体内显著降低MYC水平,并在小鼠胰腺癌CDX模型中展示了其抗肿瘤活性。 | |||
T28215 |
NT113
NT 113,NT-113 |
||
NT113 is a pan-ERBB inhibitor with high brain penetrance. NT113 is active against GBM xenografts in which wild-type EGFR or EGFRvIII is highly expressed. NT113 inhibits the growth of glioblastoma xenografts with EGFR amplification. NT113 has inhibitory ac | |||
T78075 |
GBT1118
|
Others | Others |
GBT1118是一种有效的口服血红蛋白氧亲和力变构调节剂,可增强对严重缺氧的耐受性。 | |||
T23464 |
Tocrifluor T1117
|
Others | Others |
Fluorescent form of AM 251, CB1 receptor antagonist |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01255 |
CD2 Protein, Human, Recombinant (His)
LFA-2,SRBC,T11,CD2 molecule |
Human | HEK293 Cells |
CD2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is P06729. | |||
TMPY-05421 |
CD2 Protein, Human, Recombinant (hFc)
SRBC,CD2 molecule,LFA-2,T11 |
Human | HEK293 Cells |
CD2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48 kDa and the accession number is P06729. | |||
TMPK-01054 |
CD2 Protein, Cynomolgus, Recombinant (aa 25-209, His)
SRBC,T11,LFA-3 receptor,LFA-2,CD2 |
Cynomolgus | HEK293 Cells |
The CD2 family of receptors is evolutionarily conserved and widely expressed on cells within the hematopoietic compartment. In recent years several new members have been identified with important roles in the immune system. CD2 family members regulate natural killer (NK) cell lytic activity and inflammatory cytokine production when engaged by ligands on tumor cells. | |||
TMPY-00414 |
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His)
ILT-11,CD85F,LIR-9,LIR9,LILRB7,CD85,ILT11,leukocyte... |
Human | HEK293 Cells |
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is A6NI73-1. | |||
TMPY-03959 |
CHST11 Protein, Human, Recombinant (His)
carbohydrate (chondroitin 4) sulfotransferase 11,HSA269537,C... |
Human | Baculovirus Insect Cells |
CHST11, also known as C4ST-1, belongs to the sulfotransferase 2 family. CHST11 localizes to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving CHST11 gene and IgH, t(12;14)(q23;q32), has been reported in a patient with ... | |||
TMPY-04309 |
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (hFc)
LILRB7,LIR9,leukocyte immunoglobulin-like receptor, subfamil... |
Human | HEK293 Cells |
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52 kDa and the accession number is A6NI73-1. | |||
TMPY-03069 |
LILRA5/CD85f/ILT11 Protein, Rat, Recombinant (His)
leukocyte immunoglobulin-like receptor, subfamily A (with TM... |
Rat | HEK293 Cells |
LILRA5/CD85f/ILT11 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.2 kDa and the accession number is D4A6Y0. | |||
TMPY-03097 |
LILRA5/CD85f/ILT11 Protein, Rat, Recombinant (hFc)
leukocyte immunoglobulin-like receptor, subfamily A (with TM... |
Rat | HEK293 Cells |
LILRA5/CD85f/ILT11 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.8 kDa and the accession number is D4A6Y0. | |||
TMPK-00185 |
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His & Avi)
ILT11CD85f,LIR-9,ILT11,LILRA5,CD85,LILRB7,... |
Human | HEK293 Cells |
The leukocyte immunoglobulin-like receptors (LILR) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIRs). Human LILRA5, also known as ILT11, LIR-9, and CD85f, consists of a 227 amino acid (aa) extracellular domain (ECD), a 21 aa transmembrane segment, and a 10 aa cytoplasmic tail. LILRA5 may play a role in triggering innate immune responses. Does not seem to play a role for any class I MHC a... | |||
TMPY-05230 |
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His), Biotinylated
CD85,ILT11,LIR9,ILT-11,CD85F,LIR-9,leukocyte immuno... |
Human | HEK293 Cells |
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is A6NI73-1. | |||
TMPY-05605 |
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His & Avi), Biotinylated
leukocyte immunoglobulin-like receptor, subfamily A (with TM... |
Human | HEK293 Cells |
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.5 kDa and the accession number is A6NI73-1. | |||
TMPH-01712 |
TRMT112 Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
TRMT112 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.2 kDa and the accession number is Q9UI30. |