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Targets Recommended: Fatty Acid Synthase

6

抑制剂 & 化合物

12

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T7947 FT113

Fatty Acid Synthase Metabolism
FT113 是口服具有活力的脂肪酸合酶抑制剂,对全长重组人 FASN 酶的 IC50=213 nM。在 BT474 细胞中,它抑制 FASN 的特性,IC50=90 nM。它具有抗增殖作用,在体内和体外实验中,都具有抗癌作用。
T68939 GT11

GT-11 is an inhibitor of dihydroceramides (DHCer) desaturase activity.
T79187 CT1113

CT1113是一种针对USP28和USP25的高效抑制剂,能够在体内显著降低MYC水平,并在小鼠胰腺癌CDX模型中展示了其抗肿瘤活性。
T28215 NT113

NT 113,NT-113

NT113 is a pan-ERBB inhibitor with high brain penetrance. NT113 is active against GBM xenografts in which wild-type EGFR or EGFRvIII is highly expressed. NT113 inhibits the growth of glioblastoma xenografts with EGFR amplification. NT113 has inhibitory ac
T78075 GBT1118

Others Others
GBT1118是一种有效的口服血红蛋白氧亲和力变构调节剂,可增强对严重缺氧的耐受性。
T23464 Tocrifluor T1117

Others Others
Fluorescent form of AM 251, CB1 receptor antagonist

化合物

FT113
Cat.No: T7947
Synonym:
Target: Fatty Acid Synthase
GT11
Cat.No: T68939
Synonym:
Target:
CT1113
Cat.No: T79187
Synonym:
Target:
NT113
Cat.No: T28215
Synonym: NT 113,NT-113
Target:
GBT1118
Cat.No: T78075
Synonym:
Target: Others
Tocrifluor T1117
Cat.No: T23464
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPY-01255 CD2 Protein, Human, Recombinant (His)

LFA-2,SRBC,T11,CD2 molecule

Human HEK293 Cells
CD2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is P06729.
TMPY-05421 CD2 Protein, Human, Recombinant (hFc)

SRBC,CD2 molecule,LFA-2,T11

Human HEK293 Cells
CD2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48 kDa and the accession number is P06729.
TMPK-01054 CD2 Protein, Cynomolgus, Recombinant (aa 25-209, His)

SRBC,T11,LFA-3 receptor,LFA-2,CD2

Cynomolgus HEK293 Cells
The CD2 family of receptors is evolutionarily conserved and widely expressed on cells within the hematopoietic compartment. In recent years several new members have been identified with important roles in the immune system. CD2 family members regulate natural killer (NK) cell lytic activity and inflammatory cytokine production when engaged by ligands on tumor cells.
TMPY-00414 LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His)

ILT-11,CD85F,LIR-9,LIR9,LILRB7,CD85,ILT11,leukocyte...

Human HEK293 Cells
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is A6NI73-1.
TMPY-03959 CHST11 Protein, Human, Recombinant (His)

carbohydrate (chondroitin 4) sulfotransferase 11,HSA269537,C...

Human Baculovirus Insect Cells
CHST11, also known as C4ST-1, belongs to the sulfotransferase 2 family. CHST11 localizes to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving CHST11 gene and IgH, t(12;14)(q23;q32), has been reported in a patient with ...
TMPY-04309 LILRA5/CD85f/ILT11 Protein, Human, Recombinant (hFc)

LILRB7,LIR9,leukocyte immunoglobulin-like receptor, subfamil...

Human HEK293 Cells
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52 kDa and the accession number is A6NI73-1.
TMPY-03069 LILRA5/CD85f/ILT11 Protein, Rat, Recombinant (His)

leukocyte immunoglobulin-like receptor, subfamily A (with TM...

Rat HEK293 Cells
LILRA5/CD85f/ILT11 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.2 kDa and the accession number is D4A6Y0.
TMPY-03097 LILRA5/CD85f/ILT11 Protein, Rat, Recombinant (hFc)

leukocyte immunoglobulin-like receptor, subfamily A (with TM...

Rat HEK293 Cells
LILRA5/CD85f/ILT11 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.8 kDa and the accession number is D4A6Y0.
TMPK-00185 LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His & Avi)

ILT11CD85f,LIR-9,ILT11,LILRA5,CD85,LILRB7,...

Human HEK293 Cells
The leukocyte immunoglobulin-like receptors (LILR) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIRs). Human LILRA5, also known as ILT11, LIR-9, and CD85f, consists of a 227 amino acid (aa) extracellular domain (ECD), a 21 aa transmembrane segment, and a 10 aa cytoplasmic tail. LILRA5 may play a role in triggering innate immune responses. Does not seem to play a role for any class I MHC a...
TMPY-05230 LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His), Biotinylated

CD85,ILT11,LIR9,ILT-11,CD85F,LIR-9,leukocyte immuno...

Human HEK293 Cells
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is A6NI73-1.
TMPY-05605 LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His & Avi), Biotinylated

leukocyte immunoglobulin-like receptor, subfamily A (with TM...

Human HEK293 Cells
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.5 kDa and the accession number is A6NI73-1.
TMPH-01712 TRMT112 Protein, Human, Recombinant (His & SUMO)

Human E. coli
TRMT112 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.2 kDa and the accession number is Q9UI30.

重组蛋白

CD2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01255
Species: Human
Expression System: HEK293 Cells
CD2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05421
Species: Human
Expression System: HEK293 Cells
CD2 Protein, Cynomolgus, Recombinant (aa 25-209, His)
Cat.No: TMPK-01054
Species: Cynomolgus
Expression System: HEK293 Cells
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His)
Cat.No: TMPY-00414
Species: Human
Expression System: HEK293 Cells
CHST11 Protein, Human, Recombinant (His)
Cat.No: TMPY-03959
Species: Human
Expression System: Baculovirus Insect Cells
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04309
Species: Human
Expression System: HEK293 Cells
LILRA5/CD85f/ILT11 Protein, Rat, Recombinant (His)
Cat.No: TMPY-03069
Species: Rat
Expression System: HEK293 Cells
LILRA5/CD85f/ILT11 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03097
Species: Rat
Expression System: HEK293 Cells
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00185
Species: Human
Expression System: HEK293 Cells
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05230
Species: Human
Expression System: HEK293 Cells
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05605
Species: Human
Expression System: HEK293 Cells
TRMT112 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01712
Species: Human
Expression System: E. coli
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