Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8866 |
GW779439X
|
Apoptosis; Antibacterial; CDK; Aurora Kinase | Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Microbiology/Virology |
GW779439X 属于吡唑并吡啶类,是一种金黄色葡萄球菌 PASTA 激酶 Stk1抑制剂。它是一种AURKA 抑制剂,可通过 caspases 3/7 诱导细胞凋亡。 | |||
T16944 |
STK16-IN-1
|
Others | Others |
STK16-IN-1是一种STK16激酶抑制剂(IC50:295 nM)。 | |||
T60946 |
SLK/STK10-IN-1
|
||
SLK/STK10-IN-1 是具有纳摩尔效力的 SLK 和 STK10选择性抑制剂。 | |||
T69551 |
SGC-STK17B-1
|
||
SGC-STK17B-1 is a potent and selective inhibitor of STK17B/DRAK2 kinase. | |||
T9473 |
4SC-203
|
FLT | Angiogenesis; Tyrosine Kinase/Adaptors |
4SC-203 是一种具有潜在的抗肿瘤活性的多激酶抑制剂。它对 FLT3/STK1、 FLT3 的突变形式以及 VEGFRs 具有选择性抑制作用。 | |||
T71400 |
Quizartinib HCl
|
||
Quizartinib, also know as AC220 and AC010220, is an orally available FLT3 / STK1 inhibitor with potential antineoplastic activity. Class III receptor tyrosine kinase inhibitor AC220 selectively inhibits class III receptor tyrosine kinases, including FMS-related tyrosine kinase 3 (FLT3/STK1), colony-stimulating factor 1 receptor (CSF1R/FMS), stem cell factor receptor (SCFR/KIT), and platelet derived growth factor receptors (PDGFRs), resulting in inhibition of ligand-independent leukemic cell pro... |