3
1
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12691 |
Rapamycin-d3
AY-22989-d3,Sirolimus-d3 |
Others | Others |
Rapamycin-d3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific inhibitor of mTOR(IC50 of 0.1 nM in HEK293 cells). | |||
T2145 |
Temsirolimus
NSC 683864,CCI-779,西罗莫司脂化物 |
Apoptosis; mTOR; Autophagy | Apoptosis; Autophagy; PI3K/Akt/mTOR signaling |
Temsirolimus (CCI-779) 是一种mTOR 抑制剂,IC50值为 1.76 μM。它能激活自噬,可防止心脏功能恶化。 | |||
T26309 |
Umirolimus
Biolimus-A9,TRM-986,TRM 986,TRM986,Biolimus A9 |
||
Umirolimus is a sirolimus derivative from a biodegradable polylactic acid polymer. It has enhanced anti-inflammatory and antiproliferative activity with an improved pharmacokinetic profile. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1537 |
Rapamycin
Sirolimus,AY 22989,雷帕霉素,NSC-2260804 |
Others; Endogenous Metabolite; Antibiotic; mTOR; Autophagy; Antifungal | Autophagy; Metabolism; Microbiology/Virology; Others; PI3K/Akt/mTOR signaling |
Rapamycin (AY 22989) 属于大环内酯类天然产物,是一种 mTOR 抑制剂,具有特异性(HEK293 细胞:IC50=0.1 nM)。Rapamycin 具有免疫抑制活性,并能诱导自噬。 |