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Search Results for " stk1 "

Targets Recommended: Apoptosis Antibacterial CDK Aurora Kinase

6

抑制剂 & 化合物

16

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T8866	GW779439X	Apoptosis; Antibacterial; CDK; Aurora Kinase	Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Microbiology/Virology
	GW779439X 属于吡唑并吡啶类，是一种金黄色葡萄球菌 PASTA 激酶 Stk1抑制剂。它是一种AURKA 抑制剂，可通过 caspases 3/7 诱导细胞凋亡。
T16944	STK16-IN-1	Others	Others
	STK16-IN-1是一种STK16激酶抑制剂(IC50:295 nM)。
T60946	SLK/STK10-IN-1
	SLK/STK10-IN-1 是具有纳摩尔效力的 SLK 和 STK10选择性抑制剂。
T69551	SGC-STK17B-1
	SGC-STK17B-1 is a potent and selective inhibitor of STK17B/DRAK2 kinase.
T9473	4SC-203	FLT	Angiogenesis; Tyrosine Kinase/Adaptors
	4SC-203 是一种具有潜在的抗肿瘤活性的多激酶抑制剂。它对 FLT3/STK1、 FLT3 的突变形式以及 VEGFRs 具有选择性抑制作用。
T71400	Quizartinib HCl
	Quizartinib, also know as AC220 and AC010220, is an orally available FLT3 / STK1 inhibitor with potential antineoplastic activity. Class III receptor tyrosine kinase inhibitor AC220 selectively inhibits class III receptor tyrosine kinases, including FMS-related tyrosine kinase 3 (FLT3/STK1), colony-stimulating factor 1 receptor (CSF1R/FMS), stem cell factor receptor (SCFR/KIT), and platelet derived growth factor receptors (PDGFRs), resulting in inhibition of ligand-independent leukemic cell pro...

化合物

Cat.No: T8866

Target: Apoptosis, Antibacterial, CDK, Aurora Kinase

Cat.No: T16944

Target: Others

SLK/STK10-IN-1

Cat.No: T60946

Cat.No: T69551

Cat.No: T9473

Target: FLT

Quizartinib HCl

Cat.No: T71400

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01247	FLT3 Protein, Human, Recombinant (T227M, His) FLK2,FLK-2,CD135,STK1,fms-related...	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD prot...
TMPY-05738	FLT3 Protein, Human, Recombinant (hFc) FLK2,CD135,fms-related tyrosine kinase 3,FLK-2,...	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD prot...
TMPY-01954	TIE2 Protein, Mouse, Recombinant (hFc) Tie-2,STK1,Tie2,Hyk,Cd202b,AA5170...	Mouse	HEK293
	TEK, or TIE-2, is an endothelial cell-specific receptor tyrosine kinase (RTK) that is known as a functioning molecule of vascular endothelial cells. TEK comprises a subfamily of RTK with TIE, and these two receptors play critical roles in vascular maturation, maintenance of integrity and remodeling. Targeted mutagenesis of both Tek and its agonistic ligand, Angiopoietin-1, result in embryonic lethality, demonstrating that the signal transduction pathways mediated by this receptor are crucial for...
TMPY-04575	TIE2 Protein, Mouse, Recombinant (aa 770-1122, His & GST) Cd202b,AA517024,STK1,Tie2,Tie-2,T...	Mouse	Baculovirus-Insect Cells
	TEK, or TIE-2, is an endothelial cell-specific receptor tyrosine kinase (RTK) that is known as a functioning molecule of vascular endothelial cells. TEK comprises a subfamily of RTK with TIE, and these two receptors play critical roles in vascular maturation, maintenance of integrity and remodeling. Targeted mutagenesis of both Tek and its agonistic ligand, Angiopoietin-1, result in embryonic lethality, demonstrating that the signal transduction pathways mediated by this receptor are crucial for...
TMPY-06938	FLT3 Protein, Human, Recombinant (hFc & Avi), Biotinylated fms-related tyrosine kinase 3,CD135,STK	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD prot...
TMPY-04449	CDK7 & CCNH & MNAT1 Protein, Human, Recombinant (His) HCAK,CAK1,cyclin-dependent kinase 7,p39MO1...	Human	Baculovirus-Insect Cells
	CDK7 & CCNH & MNAT1 Protein, Human, Recombinant (His) is expressed in Baculovirus-Insect Cells with His tag. The predicted molecular weight is 118.8 kDa. Accession number: P50613&P51946&P51948
TMPY-06974	TIE2 Protein, Mouse, Recombinant (His), Biotinylated AA517024,Tie2,STK1,Hyk,Tie-2,TEK ...	Mouse	HEK293
	TEK, or TIE-2, is an endothelial cell-specific receptor tyrosine kinase (RTK) that is known as a functioning molecule of vascular endothelial cells. TEK comprises a subfamily of RTK with TIE, and these two receptors play critical roles in vascular maturation, maintenance of integrity and remodeling. Targeted mutagenesis of both Tek and its agonistic ligand, Angiopoietin-1, result in embryonic lethality, demonstrating that the signal transduction pathways mediated by this receptor are crucial for...
TMPH-01172	CDK7 Protein, Human, Recombinant (His) 39 kDa protein kinase,Cyclin-dependent kinase 7,CDK-activati...	Human	Baculovirus
	CDK7 Protein, Human, Recombinant (His) is expressed in Baculovirus.
TMPH-01173	CDK7 Protein, Human, Recombinant Cyclin-dependent kinase 7,Cell division protein kinase 7,Ser...	Human	E. coli
	CDK7 Protein, Human, Recombinant is expressed in E. coli.
TMPK-00523	FLT3 Protein, Cynomolgus, Recombinant (hFc) FLT-3,FLK2,STK-1,CD135	Cynomolgus	HEK293
	The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and Stk-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes KIT, the receptor for SCF and FMS, the receptor for M-CSF. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 ...
TMPK-00416	FLT3 Protein, Human, Recombinant (His & Avi), Biotinylated STK-1,FLK2,CD135,FLT-3	Human	CHO
	The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and Stk-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes KIT, the receptor for SCF and FMS, the receptor for M-CSF. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 ...
TMPH-02094	STK11 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	STK11 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPY-03450	GSTK1 Protein, Human, Recombinant glutathione S-transferase κ1,GST,glutathione S-tran...	Human	E. coli
	GSTK1 gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. Glutathione S-transferases (GSTs) are a family of enzymes that catalyze a variety of reactions in both eukaryotes and prokaryotes. They catalyze the conjugation of reduced glutathione with potentially toxic, xenobiotic substrates, thus aiding excretion from the body. GSTK1(glutathione S-transferase kappa 1) is localized to the peroxisome and catalyzes the...
TMPY-04468	STK16 Protein, Human, Recombinant (His & NusA) MPSK,serine/threonine kinase 16,TSF1,KRCT,...	Human	E. coli
	Serine/threonine-protein kinase 16, also known as myristoylated and palmitoylated serine/threonine-protein kinase, Protein kinase PKL12, TGF-beta-stimulated factor 1, TSF-1, MPSK1 and STK16, is a membrane protein that is ubiquitously expressed at very low levels. STK16 / MPSK1 belongs to the protein kinase superfamily and Ser/Thr protein kinase family. It contains one protein kinase domain. Transforming growth factor-beta (TGF-beta) shows a variety of biological activities in various organs or c...
TMPH-01396	GSTK1 Protein, Human, Recombinant (GST)	Human	E. coli
	Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB).
TMPY-04407	LOK Protein, Human, Recombinant (His) serine/threonine kinase 10,PRO2729,LOK	Human	E. coli
	Serine / threonine-protein kinase 1, also known as Lymphocyte-oriented kinase, STK1 and LOK, belongs to the protein kinase superfamily, STE Ser / Thr protein kinase family and STE2 subfamily. Protein kinases constitute a large superfamily of enzymes with key regulatory functions in nearly all signal transmission processes of eukaryotic cells. The Ste2 family of serine/threonine kinases plays an important role in numerous cellular functions such as growth, apoptosis, and morphogenesis. STK1 is si...

重组蛋白

FLT3 Protein, Human, Recombinant (T227M, His)

Cat.No: TMPY-01247

Species: Human

Expression System: HEK293

FLT3 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05738

Species: Human

Expression System: HEK293

TIE2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-01954

Species: Mouse

Expression System: HEK293

TIE2 Protein, Mouse, Recombinant (aa 770-1122, His & GST)

Cat.No: TMPY-04575

Species: Mouse

Expression System: Baculovirus-Insect Cells

FLT3 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPY-06938

Species: Human

Expression System: HEK293

CDK7 & CCNH & MNAT1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04449

Species: Human

Expression System: Baculovirus-Insect Cells

TIE2 Protein, Mouse, Recombinant (His), Biotinylated

Cat.No: TMPY-06974

Species: Mouse

Expression System: HEK293

CDK7 Protein, Human, Recombinant (His)

Cat.No: TMPH-01172

Species: Human

Expression System: Baculovirus

CDK7 Protein, Human, Recombinant

Cat.No: TMPH-01173

Species: Human

Expression System: E. coli

FLT3 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPK-00523

Species: Cynomolgus

Expression System: HEK293

FLT3 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00416

Species: Human

Expression System: CHO

STK11 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02094

Species: Human

Expression System: E. coli

GSTK1 Protein, Human, Recombinant

Cat.No: TMPY-03450

Species: Human

Expression System: E. coli

STK16 Protein, Human, Recombinant (His & NusA)

Cat.No: TMPY-04468

Species: Human

Expression System: E. coli

GSTK1 Protein, Human, Recombinant (GST)

Cat.No: TMPH-01396

Species: Human

Expression System: E. coli

LOK Protein, Human, Recombinant (His)

Cat.No: TMPY-04407

Species: Human

Expression System: E. coli

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