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Targets Recommended: GPR

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T2701	GSK1292263	GPR	Endocrinology/Hormones; GPCR/G Protein
	GSK1292263 是口服具有活性的 GPR119 激动剂，对人和大鼠 GPR119的pEC50分别为 6.9 和 6.7，它可用于研究 2 型糖尿病 (T2DM) 。
T24105	GSK121 GSK-121,GSK 121	PAD	Chromatin/Epigenetic
	GSK121 Trifluoroacetate 是PAD4的选择性抑制剂。
T2079	GSK126 GSK2816126A,EZH2 inhibitor	Histone Methyltransferase	Chromatin/Epigenetic
	GSK126 (GSK2816126A) 是一种选择性的EZH2甲基转移酶抑制剂，IC50为 9.9 nM。
T32001	GSK124576A GSK-124576A,GSK 124576A
	GSK124576A is a bioactive chemical.
T35897	ASK120067
	ASK120067 is a potent and orally active inhibitor of EGFRT790M (IC50:0.3 nM) with selectivity over EGFRWT (IC50:6.0 nM). ASK120067 is a third-generation EGFR-TKI for the research of non-small cell lung cancer (NSCLC)[1]. In the in vitro kinase assay ASK120067 potently inhibits the EGFR L858R/T790M and EGFR T790M resistant mutants with IC50 values of 0.3 nM and 0.5 nM, respectively, as well as the EGFRexon19del sensitizing mutant (IC50= 0.5 nM). The 50 of ASK120067 against wild-type EGFR (EGFRWT...

化合物

Synonym: GSK-121,GSK 121

Target: PAD

GSK126

Cat.No: T2079

Synonym: GSK2816126A,EZH2 inhibitor

Target: Histone Methyltransferase

GSK124576A

Cat.No: T32001

Synonym: GSK-124576A,GSK 124576A

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-05579	PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated PRR1,ED4,PVRR,nectin-1,OFC7,SK-12,CD111,CL...	Human	HEK293 Cells
	PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and the accession number is Q15223-1.
TMPK-00313	Nectin-1 Protein, Human, Recombinant (His & Avi), Biotinylated HIgRPVRR,OFC7,CLPED1,SK-12,MGC142031,HIgR,...	Human	HEK293 Cells
	Nectin-1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 36.9 kDa and the accession number is Q15223-1.
TMPK-00312	Nectin-1 Protein, Human, Recombinant (His & Avi) PVRR1,HIgRPVRR,PVRL1,CLPED1,MGC142031,SK-12	Human	HEK293 Cells
	Nectin-1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 36.9 kDa and the accession number is Q15223.
TMPY-01572	PVRL1/NECTIN1 Protein, Human, Recombinant (His) HVEC,ED4,PRR1,PVRR1,nectin-1,HIgR,poliovirus receptor-relate...	Human	HEK293 Cells
	PVRL1/NECTIN1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.4 kDa and the accession number is Q15223-1.
TMPY-01571	PVRL1/NECTIN1 Protein, Human, Recombinant (hFc) HV1S,ED4,poliovirus receptor-related 1 (herpesvirus entry me...	Human	HEK293 Cells
	PVRL1/NECTIN1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and the accession number is Q15223-1.