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Targets Recommended: mTOR Autophagy

9

抑制剂 & 化合物

1

天然产物

6

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T67914	Insecticidal agent 364	mTOR; Autophagy	Autophagy; PI3K/Akt/mTOR signaling
	Insecticidal agent 364是一种雷帕霉素激酶靶蛋白的选择性小分子抑制剂。Insecticidal agent 364具有抗肿瘤活性，通过抑制mTOR, Insecticidal agent 364旨在破坏参与癌细胞生长和存活的信号通路，从而潜在地抑制肿瘤生长。
T82064	Insecticidal agent 6	Parasite	Microbiology/Virology
	Insecticidal agent 6（化合物 Im）是昆虫兰尼碱受体（RyRs）的抑制剂，该化合物对 S. frugiperda RyRs 具有强效的抑制作用，其 EC50 值为0.6308 µM。该化合物在鳞翅目害虫中展现出卓越的杀虫效果，适用于病虫害研究。
T32164	Insect repellent M 3535
	Insect repellent M 3535 is a bug repellant.
T81087	Stick Insect Hypertrehalosaemic Factor II
	Stick Insect Hypertrehalosaemic Factor II为合成肽，展现出与天然样品一致的FAB光谱、反相高效液相色谱特性以及生物活性，适用于高海藻糖效应的研究。
T79122	Insecticidal agent 2	Parasite	Microbiology/Virology
	Insecticidal agent 2 (example 2)为一种杀虫剂，展现对害虫的强效生长延迟效能。
T79762	Insecticidal agent 4
	4 (IA-8) 是一款针对分枝杆菌具有显著杀虫效果的芳基异恶唑啉衍生物。
T82066	Insecticidal agent 1
	Insecticidal agent 1 展示出比叶绿酮和川楝素更高的杀虫效力。
T82065	Insecticidal agent 3
	Insecticidal agent 3 是一种昆虫生长调节剂 (IGRs)，特别针对 OfChtI, OfChtII 和 OfChi-h 的多几丁质酶抑制剂，Ki 值分别为 0.8 μM，11.9 μM 和 2.3 μM。该化合物通过扰乱正常生长和蜕皮过程，对两种鳞翅目害虫具有显著的杀虫活性。
T38357	1,3,6,8-Pyrenetetrasulfonic Acid (sodium salt hydrate)
	1,3,6,8-Pyrenetetrasulfonic acid is an intermediate in the synthesis of the color additive pyranine.1It has been used to stabilize intermolecular interactions for the crystallization ofL. mexicanapyruvate kinase.2 1.Jitian, S., White, S.R., Yang, H.-H.W., et al.Conventional high-performance liquid chromatography versus derivative spectrophotometry for the determination of 1,3,6-pyrenetrisulfonic acid trisodium salt and 1,3,6,8-pyrenetetrasulfonic acid tetrasodium salt in the color additive D&C G...

化合物

Insecticidal agent 364

Cat.No: T67914

Target: mTOR, Autophagy

Insecticidal agent 6

Cat.No: T82064

Target: Parasite

Insect repellent M 3535

Cat.No: T32164

Stick Insect Hypertrehalosaemic Factor II

Cat.No: T81087

Insecticidal agent 2

Cat.No: T79122

Target: Parasite

Insecticidal agent 4

Cat.No: T79762

Insecticidal agent 1

Cat.No: T82066

Insecticidal agent 3

Cat.No: T82065

1,3,6,8-Pyrenetetrasulfonic Acid (sodium salt hydrate)

Cat.No: T38357

Cat. No.	Product Name	Target	Signaling Pathways
TN6027	Pedatisectine F 2-Methyl-6-(1,2,3,4-tetrahydroxybutyl)pyrazine
	Pedatisectine F是一种天然产物，属于天南星科半夏属，其产品编号为 TN6027，CAS号为 206757-32-6。Pedatisectine F可用作对照参考。

天然产物

Pedatisectine F

Cat.No: TN6027

Synonym: 2-Methyl-6-(1,2,3,4-tetrahydroxybutyl)pyrazine

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00817	Granzyme B/GZMB Protein, Human, Recombinant (His) CGL1,CTLA1,CSP-B,CTSGL1,HLP,SECT,CSPB,granzyme B (g...	Human	HEK293 Cells
	Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the target cells depending on another membrane-binding granule protein, perforin, results in the activation of effector caspases and mitochondrial depolarization through caspase-dependent and -independent pathways, and consequently induces rapid cell apoptosis. Over 3 substrates of G...
TMPK-00596	SECTM1 Protein, Human, Recombinant (hFc) SECTM1,K-12	Human	HEK293 Cells
	SECTM1 is a T/NK cell "co-stimulatory" molecule that is expressed in the peripheral blood by neutrophils and monocytes.Human monocytic cells also displayed a pronounced negative regulation of SECTM1 mRNA expression by LPS, while at the protein level SECTM1 expression was also shown to be regulated by IFN and LPS. This tight regulation of SECTM1 gene expression and rapid upregulation highlights its relevance in the innate immune response.
TMPH-03626	Beta-mammal/insect toxin Ts1 Protein, Tityus serrulatus, Recombinant (His & Myc) Toxin II-11,Beta-like toxin Ts1,Ts7,Beta-mammal/insect	Tityus serrulatus	Baculovirus Insect Cells
	Beta-mammal/insect toxin Ts1 Protein, Tityus serrulatus, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 10.8 kDa and the accession number is P15226.
TMPH-03627	Beta-mammal/insect toxin Ts1 Protein, Tityus serrulatus, Recombinant (E. coli, His & Myc) Ts VII,Beta-like toxin Ts1,Toxin II-11,Ts7,Tityustoxin VII,P...	Tityus serrulatus	E. coli
	Beta-mammal/insect toxin Ts1 Protein, Tityus serrulatus, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 14.3 kDa and the accession number is P15226.
TMPY-02045	SECTM1 Protein, Human, Recombinant (His) K12,secreted and transmembrane 1	Human	HEK293 Cells
	Secreted and transmembrane 1 (SECTM1), also known as K12, is a transmembrane and secreted protein with characteristics of a type 1a transmembrane protein of SECTM family. It is found in a perinuclear Golgi-like pattern and thought to be involved in hematopoietic and/or immune system processes. The human K12 protein has been shown to be primarily expressed in spleen, prostate, testis, small intestine, and in peripheral blood leukocytes. The K12 protein is expressed on the cell surface in such sma...
TMPJ-00438	SECTM1A Protein, Mouse, Recombinant (His) Sectm1a	Mouse	HEK293 Cells
	SECTM1A (secreted and transmembrane 1A), is 192 amino acid (aa) protein, appears to share structural and functional characteristics with other SECTM1 proteins. Human SECTM1 can be found either found as an approximately 27 kDa intracellular type I transmembrane protein that shows a perinuclear, Golgi like staining pattern, or as a 20 kDa soluble, secreted form, and is produced by some myeloid cells and by thymic epithelia and fibroblasts. Stimulation with IFN gamma is often necessary to detect h...

重组蛋白

Granzyme B/GZMB Protein, Human, Recombinant (His)

Cat.No: TMPY-00817

Species: Human

Expression System: HEK293 Cells

SECTM1 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00596

Species: Human

Expression System: HEK293 Cells

Beta-mammal/insect toxin Ts1 Protein, Tityus serrulatus, Recombinant (His & Myc)

Cat.No: TMPH-03626

Species: Tityus serrulatus

Expression System: Baculovirus Insect Cells

Beta-mammal/insect toxin Ts1 Protein, Tityus serrulatus, Recombinant (E. coli, His & Myc)

Cat.No: TMPH-03627

Species: Tityus serrulatus

Expression System: E. coli

SECTM1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02045

Species: Human

Expression System: HEK293 Cells

SECTM1A Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00438

Species: Mouse

Expression System: HEK293 Cells

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