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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T10111	3-Deazaadenosine hydrochloride	Others; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	3-Deazaadenosine hydrochloride 是 S-腺苷高半胱氨酸水解酶的抑制剂，Ki 值为 3.9 µM。它具有抗炎、抗增殖和抗 HIV 活性。
T22231	Adenosine Dialdehyde (ADOX) 腺苷二醛,Periodate-oxidized adenosine,Adenosine, periodate oxidized,Adenox,Adenosinedialdehyde	Others	Others
	Adenosine Dialdehyde (Periodate-oxidized adenosine) 是嘌呤核苷类似物，是S-腺苷高半胱氨酸水解酶（SAHH）的有效抑制剂（Ki=3.3nM）。Adenosine Dialdehyde 在体内具有较强的抗肿瘤活性。
T6360	3-deazaneplanocin A HCl	Others; Histone Methyltransferase	Chromatin/Epigenetic; Others
	3-deazaneplanocin A HCl 是组蛋白甲基转移酶 (EZH2) 和 S-腺苷同型半胱氨酸水解酶 (AHCY) 抑制剂。
T10111L	3-Deazaadenosine	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 µM, and it has anti-inflammatory, anti-proliferative and anti-HIV activity.
T69264	Aristeromycin diphosphate
	Aristeromycin diphosphate is an inhibitor of S-adenosylhomocysteine hydrolase (AHCY), inducing miR-26a and regulating oncogenic EZH2 expression, showing high inhibitory activity against AHCY, and causing growth inhibition of prostate cancer.
T35766	SAHO
	SAHO is a sulfoxide form of the methyl donor S-(5'-adenosyl)-L-methionine chloride and a substrate for radical SAM enzymes.1It is reductively cleaved to S-adenosylhomocysteine , 5'-deoxyadenosine , and 5'-thioadenosine sulfenic acid by the radical SAM enzymes NosL or NosN. 1.Mandalapu, D., Ji, X., and Zhang, Q.Reductive cleavage of sulfoxide and sulfone by two radical S-adenosyl-L-methionine enzymesBiochemistry58(1)36-39(2019)
T74764	Adenosylhomocysteinase
	Adenosylhomocysteinase (SAHH; AHCY) 是一种高度保守的酶。Adenosylhomocysteinase 可逆催化 S-腺苷同型半胱氨酸 (SAH) 生成腺苷和 L-同型半胱氨酸。血清外泌体 Adenosylhomocysteinase 水平可作为 HBV-LC 患者预后的生物标志物。

化合物

3-Deazaadenosine hydrochloride

Cat.No: T10111

Synonym:

Target: Others, HIV Protease

Adenosine Dialdehyde (ADOX)

Cat.No: T22231

Synonym: 腺苷二醛,Periodate-oxidized adenosine,Adenosine, periodate oxidized,Adenox,Adenosinedialdehyde

Target: Others

3-deazaneplanocin A HCl

Cat.No: T6360

Synonym:

Target: Others, Histone Methyltransferase

3-Deazaadenosine

Cat.No: T10111L

Synonym:

Target: HIV Protease

Aristeromycin diphosphate

Adenosylhomocysteinase

Cat.No: T74764

Synonym:

Target:

Cat. No.	Product Name	Target	Signaling Pathways
TQ0208	SAH SAH (S-Adenosylhomocysteine),S-(5'-腺苷)-L-高半胱氨酸	Others; Endogenous Metabolite	Metabolism; Others
	SAH (SAH (S-Adenosylhomocysteine)) 是氨基酸衍生物，是几种代谢途径中的调节剂。SAH 是腺苷和半胱氨酸合成的中间体。SAH 是 METTL3-METTL14 异二聚体复合物的抑制剂，IC50=0.9 µM。
T10369	Aristeromycin	Others	Others
	Aristeromycin is an adenosine analog and an antibiotic and. It is a potent S-adenosylhomocysteine hydrolase (AHCY) inhibitor.