搜索结果

Search Results for " rasagiline "

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T1119	Rasagiline 雷沙吉兰,AGN1135,TVP1012	BCL; MAO; Monoamine Oxidase	Apoptosis; Metabolism; Neuroscience
	Rasagiline (AGN1135) 是不可逆的、高效的、选择性的线粒体单胺氧化酶 (MAO) 抑制剂，抑制大鼠脑 MAO B 和 MAO A 的 IC50分别为 4.43 nM 和 412 nM。
T6962	Rasagiline Mesylate TVP1012,甲磺酸雷沙吉兰,AGN1135,Azilect	Apoptosis; MAO; Autophagy; Monoamine Oxidase	Apoptosis; Autophagy; Metabolism; Neuroscience
	Rasagiline Mesylate (AGN1135) 是一种高效的，不可逆的选择性线粒体单胺氧化酶 (MAO) 抑制剂，抑制大鼠脑 MAO B 和 MAO A 的IC50分别为 4.43 nM 和 412 nM。
T36903	Rasagiline-13C3 (mesylate) Rasagiline-13C3 (mesylate)
	Rasagiline-13C3is intended for use as an internal standard for the quantification of rasagiline by GC- or LC-MS. Rasagiline is an inhibitor of monoamine oxidase B (MAO-B; IC50= 4.43 nM for the rat brain enzyme).1It is selective for MAO-B over MAO-A (IC50= 412 nM for the rat brain enzyme). It inhibits serum and NGF withdrawal-induced apoptosis of PC12 cells when used at concentrations ranging from 0.01 to 100 μM.2Rasagiline inhibits rat brain MAO-Bin vivo(ED50= 0.1 mg/kg).1It reduces cerebral ede...
T71910	Racemic rasagiline
	Racemic rasagiline，也称为 AGN-1135，是一种单胺氧化酶 B 型抑制剂(MAOI)。然而，在食用富含酪胺的食物的患者中，这种药物的应用可能导致致命的高血压危象。TVP-1022是雷沙吉兰的(S)异构体，具有心脏保护剂的作用。
T13252	(S)-Rasagiline TVP1022,(S)-雷沙吉兰,S-PAI	Others	Others
	(S)-Rasagiline is rasagiline S-isomer, and is an agent of anti-Parkinson.
T13252L	(S)-Rasagiline mesylate TVP1022 (mesylate),(S)-雷沙吉兰甲磺酸,S-PAI mesylate	Others	Others
	(S)-Rasagiline mesylate is rasagiline S-isomer, and is an agent of anti-Parkinson.
T12693	Rasagiline 13C3 mesylate racemic TVP1012 13C3 racemic,AGN1135 13C3 racemic	Others	Others
	Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible monoamine oxidase inhibitor.
T73530	2-PAT
	2-PAT 是一种 Rasagiline 和 Selegiline 的类似物，也是可逆的 MAO-A 抑制剂，IC50为 0.721 µM。2-PAT 是 MAO-B 的灭活剂，IC50为 14.6 µM。2-PAT 具有用于帕金森病和抑郁症研究的潜力。