Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7370 |
Talarozole
R115866,他拉罗唑 |
Others; P450; Retinoid Receptor; Autophagy | Autophagy; Metabolism; Others |
Talarozole (R115866) 是一种口服性全反式维甲酸代谢阻断剂,可抑制 CYP26A1 和 CYP26B1,IC50 分别为 5.4 和 0.46 nM。它用于治疗痤疮、牛皮癣和其他角化疾病。 | |||
T13422 | (-)-Talarozole | Others | Others |
(-)-Talarozole is a potent retinoic acid metabolism inhibitor. | |||
T13422L |
Talarozole (R enantiomer)
(R)-Talarozole,Talarozole R enantiomer |
Others | Others |
Talarozole R enantiomer is a potent and selective inhibitor of cytochrome P450 26-mediated breakdown of endogenous all-trans retinoic acid. |