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Cat. No. | Product Name | Target | Signaling Pathways |
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T0939 |
Phenytoin
苯妥英,Diphenylhydantoin,5,5-Diphenylhydantoin |
Virus Protease; Sodium Channel | Membrane transporter/Ion channel; Microbiology/Virology |
Phenytoin (5,5-Diphenylhydantoin) 是一种有效的电压门控钠离子通道阻滞剂,可减少小鼠乳腺肿瘤的生长和转移,具有抗癫痫活性。 | |||
T0008 |
Phenytoin sodium
5,5-Diphenylhydantoin sodium salt,Diphantoine,苯妥英钠,Dilantin sodium,Diphenylhydantoin Sodium |
Virus Protease; Sodium Channel | Membrane transporter/Ion channel; Microbiology/Virology |
Phenytoin sodium (Diphantoine) 是一种有效的电压门控钠离子通道阻滞剂,可减少小鼠乳腺肿瘤的生长和转移,具有抗癫痫活性。 | |||
T68918 |
Phenytoin-d10
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Phenytoin-d10 is intended for use as an internal standard for the quantification of phenytoin by GC- or LC-MS. Phenytoin is an anticonvulsant agent and active metabolite of fosphenytoin. Phenytoin is formed from fosphenytoin by tissue phosphatases. It inhibits neuronal voltage-gated sodium channels in a voltage-dependent manner. Phenytoin reduces the neuronal firing frequency and decreases the amplitude of excitatory post-synaptic potentials (EPSPs) in electrically stimulated rat corticostriatal... | |||
T7066 |
Fosphenytoin disodium
Fosphenytoin sodium,ACC-9653,磷苯妥英钠 |
Sodium Channel | Membrane transporter/Ion channel |
Fosphenytoin disodium (ACC-9653) 是 phenytoin 的前体药物,具有抗惊厥等活性。它是电压门控钠通道阻滞剂。 | |||
T61354 |
Fosphenytoin
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Others | Others |
Fosphenytoin 是一种磷酸酯前药,可替代静脉注射苯妥英,用于急性干预癫痫发作。Fosphenytoin 在肠胃外给药可水解成具有抗惊厥作用的苯妥英。Fosphenytoin 可用于多种给药方式,如静脉注射和腹腔注射。 | |||
T21425 |
Mephenytoin
Mesantoin,Methoin,Insulton,Phenantoin,美芬妥因,Methylphenetoin |
P450 | Metabolism |
Mephenytoin (Phenantoin) 是 CYP2C19 及 CYP2B6 的底物,是一种抗惊厥剂。 | |||
T21529 |
(S)-Mephenytoin
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Others | Others |
(S)-Mephenytoin 是一种抗惊厥剂。(S)-Mephenytoin 作为细胞色素 P450 (CYP) 同种型 CYP2C19 的底物,可用于分析细胞色素 P450 代谢。 | |||
T36839 |
(R)-Mephenytoin
R-Mephenytoin,(R)-Mephenytoin,(–)-Mephenytoin |
Others | Others |
(R)-Mephenytoin ((–)-Mephenytoin) 是 Mephenytoin 的 R-对映体,Mephenytoin 是一种抗惊厥药。 | |||
T29410 |
3-Hydroxymephenytoin
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3-Hydroxymephenytoin is a bioactive chemical. | |||
TD1228 |
ETHOTOIN
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Ethotoin (Peganone) 是一种用于癫痫研究的,具有口服活性的抗惊厥剂。Ethotoin 是一种海因类化合物,与苯妥英相似。 | |||
T25307 |
Denzimol hydrochloride
REC 15-1533 |
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Denzimol hydrochloride 是一种新型抗惊厥药物,能抑制电性和化学性诱发的强直性癫痫发作,但不能阻止阵挛性癫痫发作。其表现与苯妥英和卡马西平相似,但与巴比妥类和苯二氮卓类不同。 |
Cat. No. | Product Name | Target | Signaling Pathways |
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T10147 |
4-Hydroxymephenytoin
(+/-)-4'-Hydroxymephenytoin |
Others; Drug Metabolite | Metabolism; Others |
4-Hydroxymephenytoin ((+/-)-4'-Hydroxymephenytoin) 是抗癫痫药 mephenytoin 的代谢产物。Mephenytoin 是 CYP2C19的配体。 |