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Targets Recommended: FAAH

40

抑制剂 & 化合物

1

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T28353	PDP-EA	FAAH	Metabolism; Neuroscience
	PDP-EA 是脂肪酸酰胺水解酶 (FAAH) 的激活剂，可增强 FAAH 的酰胺水解酶活性。
T18531	PDP-Pfp	Others	Others
	PDP-Pfp is a reducible ADC linker primarily utilized for targeting agents aimed at the extracellular loop 1 (ECL1) of TM4SF1, a member of the transmembrane 4 L6 family, as supported by reference [1].
T18530	PDP-C1-Ph-Val-Cit	Others	Others
	PDP-C1-Ph-Val-Cit is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
T74302	DSPE-PEG-PDP
	DSPE-PEG-PDP 是一种磷脂 PEG 偶联物，可用于药物递送应用。
TP2036L	DPDPE TFA (88373-73-3 free base) DPDPE TFA	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	DPDPE TFA 是选择性 δ-阿片受体激动剂肽，在体内具有镇痛作用。
T19955	Biotin-HPDP Pyridyldisulfide-biotin,Pyridyldithiol-biotin	Others	Others
	Biotin-HPDP (Pyridyldithiol-biotin) 是一种巯基反应性生物素化试剂。
T6741	SPDP SPDP Crosslinker	Others	Others
	SPDP 是一种短链交联剂，用于通过 NHS 酯和吡啶基二硫醇反应基团与半胱氨酸巯基形成可切割（可还原）的二硫键，实现胺与巯基的共轭。它是一种可降解的 ADC 连接剂，可用于合成抗体偶联药物。
T18709	SPDP-PEG12-acid	Others	Others
	SPDP-PEG12-acid is a cleavable 12-unit polyethylene glycol (PEG) linker utilized for the synthesis of antibody-drug conjugates (ADCs)[1].
T18711	SPDP-PEG24-acid	Others	Others
	SPDP-PEG24-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T77286	DSPE-SPDP
	DSPE-SPDP，一种磷脂分子，能够在水中自行定向并形成脂质双层，适用于多种生化研究。
T37235	(±)16(17)-EpDPA (±)16,17-EpDPE,(±)16,17 EDP,(±)16,17-epoxy Docosapentaenoic Acid,(±)16,17-epoxy DPA,(±)16(17)-EpDPA
	EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators.[1],[2]Cytochrome P450 (CYP450) metabolism of polyunsaturated fatty acids produces epoxides such as (±)14(15)-EET which are prime candidates for the actual active mediator.[3] However, the CYP450 metabolites of eicosapentaenoic acid and docosahex...
T37241	(±)4(5)-EpDPA methyl ester
	(±)4(5)-EpDPA methyl ester is a derivative of (±)4(5)-EpDPA which is stable enough to ship and handle routinely. The active free acid can be regenerated from the methyl ester by careful base hydrolysis. (±)4(5)EpDPA is a CYP450 metabolite of DHA which can be further metabolized to the diol metabolite. There are no published reports on the biological activity of (±)4(5)-EpDPA methyl ester at this time.
T16915	SPDP-C6-NHS ester	Others	Others
	SPDP-C6-NHS ester is an alkyl/ether-based linker utilized in the synthesis of PROTACs[1].
T18715	SPDP-PEG7-acid	Others	Others
	SPDP-PEG7-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T16918	SPDP-PEG6-NHS ester	Others	Others
	SPDP-PEG6-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18714	SPDP-PEG5-acid	Others	Others
	SPDP-PEG5-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T15724	LC-PEG8-SPDP	Others	Others
	LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].
T36218	19R(20S)-EpDPA
	19R(20S)-EpDPA is an oxylipin and a metabolite of docosahexaenoic acid .1,2It is formed from DHA by various cytochrome P450 (CYP) isoforms in a stereoselective manner.219R(20S)-EpDPA (30 nM) prevents calcium-induced increases in the spontaneous beating of isolated neonatal rat cardiomyocytes (NRCMs).3 1.Cinelli, M.A., Yang, J., Scharmen, A., et al.Enzymatic synthesis and chemical inversion provide both enantiomers of bioactive epoxydocosapentaenoic acidsJ. Lipid Res.59(11)2237-2252(2018) 2.Lucas...
T18535	PEG4-SPDP	Others	Others
	PEG4-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).
TP2036	DPDPE	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	DPDPE 是选择性 δ-阿片受体激动剂肽，在体内具有镇痛作用。
T17834	DM4-SPDP	Others	Others
	DM4-SPDP, a drug-linker conjugate, integrates the antitubulin agent DM4 with the linker SMCC, facilitating the creation of antibody drug conjugates[1]. Additionally, SPDP serves as a short-chain crosslinker enabling amine-to-sulfhydryl conjugation, leveraging NHS-ester and pyridyldithiol groups to establish cleavable (reducible) disulfide bonds with cysteine sulfhydryls[2][3].
T35493	(±)10(11)-EpDPA
	Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)10(11)-EpDPA is a docosahexaenoic acid epoxygenase metabolite, derived via epoxidation of the 10,11-double bond of DHA. It has been detected in rat brain and spinal cord, as well as human serum, and acts as a substrate for soluble epoxide hydrolase with a Km value of 5.1 μM. (±)10(11)-EpDPA and other epoxy metabolites of DHA are reported to demonstrate antihyperalgesic activity in infla...
T18733	Sulfo-SPDP-C6-NHS sodium	Others	Others
	Sulfo-SPDP-C6-NHS sodium is a sodium salt form of a cleavable ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
T18710	SPDP-PEG12-NHS ester	Others	Others
	SPDP-PEG12-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18716	SPDP-PEG9-acid	Others	Others
	SPDP-PEG9-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T16916	SPDP-PEG4-acid	Others	Others
	SPDP-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18712	SPDP-PEG24-NHS ester	Others	Others
	SPDP-PEG24-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T16917	SPDP-PEG4-NHS ester	Others	Others
	SPDP-PEG4-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T37238	(±)19(20)-EpDPA
	EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators. Cytochrome P450 (CYP450) metabolism of polyunsaturated fatty acids produces epoxides such as (±)14(15)-EpETrE which are prime candidates for the actual active mediator. However, the CYP450 metabolites of eicosapentaenoic acid and docosahexaenoic...
T35497	(±)7(8)-EpDPA
	Docosahexaenoic acid is the most abundant ω-3 fatty acid in neural tissues, especially in the brain and retina. (±)7(8)-EpDPA is an epoxide derivative of DHA that is generated by the action of cytochrome P450 epoxygenases. It is naturally occurring in plasma and brain and spinal cord tissues and is increased following dietary supplementation with ω-3 fatty acids. (±)7(8)-EpDPA and other epoxy metabolites of DHA modulate receptor and channel activities to evoke diverse effects, such as promoting ...
T18725	Sulfo-LC-SPDP	Others	Others
	Sulfo-LC-SPDP is a heterobifunctional crosslinker characterized by its thiol-cleavable and membrane impermeable properties.
T60528	PDPOB
	PDPOB 是一种苯基羧酸衍生物，具有用于脑缺血研究的潜力。PDPOB 被证明可以防止 SH-SY5Y 细胞中 OGD/R 诱发的多方面神经元退化，减轻的线粒体功能障碍、氧化应激和细胞凋亡证明了这一点。
T18525	PC SPDP-NHS carbonate ester	Others	Others
	PC SPDP-NHS carbonate ester is a cleavable linker compound utilized in the synthesis of antibody-drug conjugates (ADCs)[1].
T38597	SPDP-sulfo
	SPDP-sulfo is a cleavable linker vital in ADC synthesis. SPDP-sulfo joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
T33904	PDPH Crosslinker PDPH Cross linker,SPDP Hydrazide,PDPH Cross-linker
	PDPH crosslinker(SPDP Hydrazide) is a lytic heterobisfunctional protein crosslinker.
T35496	(±)13(14)-EpDPA
	Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)13(14)-EpDPA is a docosahexaenoic acid epoxygenase metabolite, derived via epoxidation of the 13,14-double bond of DHA. It has been detected in rat brain and spinal cord and is a preferred substrate for soluble epoxide hydrolase with a Km value of 3.2 μM. (±)13(14)-EpDPA demonstrates antihyperalgesic activity in inflammatory and neuropathic pain models. (±)13(14)-EpDPA and other epoxy m...
T18708	SPDP-C6-Gly-Leu-NHS ester	Others	Others
	SPDP-C6-Gly-Leu-NHS ester is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
T18713	SPDP-PEG36-NHS ester	Others	Others
	SPDP-PEG36-NHS ester is a PEG ADC linker consisting of 36 units, characterized by cleavability. It plays a crucial role in the synthesis of antibody-drug conjugates (ADCs)[1].
T14908	CCT367766	PROTACs	PROTAC
	CCT367766 是一种强效的、基于 PROTAC 的第三代异多功能 pirin 靶向蛋白降解探针（PDP），能在低浓度下消耗 pirin 蛋白的表达。CCT367766 对 CRBN-DDB1 复合物的IC50 值为 490 nM。CCT367766 与重组 pirin 和 CRBN 具有良好的亲和力，Kd 值分别为 55 nM 和 120 nM。CCT367766 是一种有效的口服活性蛋白，在低浓度时就可以减少 pirin 蛋白的表达。
T77915	CCT367766 formic	PROTACs	PROTAC
	CCT367766 formic 是一款有效的口服第三代异功能蛋白降解探针(PROTAC)，基于Cereblon配体，能在低浓度降低pirin蛋白表达。该化合物对CRBN-DDB1复合物具中等亲和力，IC50值为490 nM；同时，对重组pirin和CRBN的亲和力良好，Kd值分别为55 nM和120 nM。CCT367766 formic作为化学工具，对研究某些未开发蛋白质具有重要价值。

化合物

Cat.No: T28353

Target: FAAH

Cat.No: T18531

Target: Others

PDP-C1-Ph-Val-Cit

Cat.No: T18530

Target: Others

Cat.No: T74302

DPDPE TFA (88373-73-3 free base)

Cat.No: TP2036L

Synonym: DPDPE TFA

Target: Opioid Receptor

Cat.No: T19955

Synonym: Pyridyldisulfide-biotin,Pyridyldithiol-biotin

Target: Others

Cat.No: T6741

Synonym: SPDP Crosslinker

Target: Others

SPDP-PEG12-acid

Cat.No: T18709

Target: Others

SPDP-PEG24-acid

Cat.No: T18711

Target: Others

Cat.No: T77286

(±)16(17)-EpDPA

Cat.No: T37235

Synonym: (±)16,17-EpDPE,(±)16,17 EDP,(±)16,17-epoxy Docosapentaenoic Acid,(±)16,17-epoxy DPA,(±)16(17)-EpDPA

(±)4(5)-EpDPA methyl ester

Cat.No: T37241

SPDP-C6-NHS ester

Cat.No: T16915

Target: Others

Cat.No: T18715

Target: Others

SPDP-PEG6-NHS ester

Cat.No: T16918

Target: Others

Cat.No: T18714

Target: Others

Cat.No: T15724

Target: Others

Cat.No: T36218

Cat.No: T18535

Target: Others

Cat.No: TP2036

Target: Opioid Receptor

Cat.No: T17834

Target: Others

(±)10(11)-EpDPA

Cat.No: T35493

Sulfo-SPDP-C6-NHS sodium

Cat.No: T18733

Target: Others

SPDP-PEG12-NHS ester

Cat.No: T18710

Target: Others

Cat.No: T18716

Target: Others

Cat.No: T16916

Target: Others

SPDP-PEG24-NHS ester

Cat.No: T18712

Target: Others

SPDP-PEG4-NHS ester

Cat.No: T16917

Target: Others

(±)19(20)-EpDPA

Cat.No: T37238

Cat.No: T35497

Cat.No: T18725

Target: Others

Cat.No: T60528

PC SPDP-NHS carbonate ester

Cat.No: T18525

Target: Others

Cat.No: T38597

PDPH Crosslinker

Cat.No: T33904

Synonym: PDPH Cross linker,SPDP Hydrazide,PDPH Cross-linker

(±)13(14)-EpDPA

Cat.No: T35496

SPDP-C6-Gly-Leu-NHS ester

Cat.No: T18708

Target: Others

SPDP-PEG36-NHS ester

Cat.No: T18713

Target: Others

Cat.No: T14908

Target: PROTACs

CCT367766 formic

Cat.No: T77915

Target: PROTACs

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00714	CD5L Protein, Mouse, Recombinant (His) 42010,AAC-11,Sp-alpha,Pdp,Api6,AI047839,CT2,CD5 mol...	Mouse	HEK293 Cells
	CD5L Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is Q9QWK4.

重组蛋白

CD5L Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00714

Species: Mouse

Expression System: HEK293 Cells

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