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Cat. No. Product Name Target Signaling Pathways
TP1070L PACAP (1-27), human, ovine, rat acetate

PACAP 1-27 acetate,PACAP (1-27), human, ovine, rat acetate(127317-03-7 free base)

PACAP GPCR/G Protein
PACAP (1-27), human, ovine, rat acetate (PACAP 1-27 acetate)(127317-03-7 free base) 是一种新的神经肽,最初从牛下丘脑中分离出来,也存在于人和大鼠中。
TP1878L PACAP 1-38 acetate

PACAP GPCR/G Protein
PACAP 1-38 acetate 是一种垂体腺苷酸环化酶激活多肽 (PACAP) 类似物。它与 PACAP I 型受体 (IC50 = 4 nM) 和 PACAP II 型 VIP2 受体 (IC50 = 1 nM) 结合,但不与 PACAP II 型 VIP1 受体结合。
TP1618L PACAP-38 (31-38), human, mouse, rat acetate

PACAP-38 (31-38), human, mouse, rat acetate(138764-85-9 Free base)

PACAP GPCR/G Protein
PACAP-38 (31-38), human, mouse, rat acetate 是 PAC1 受体的激活剂。PACAP-38 (31-38), human, mouse, rat acetate 对交感神经元 NPY 和儿茶酚胺的产生具有强效、有效和持续的刺激作用,可用于神经营养和神经保护研究。
TP1722L PACAP (6-38), human, ovine, rat acetate

PACAP GPCR/G Protein
PACAP (6-38), human, ovine, rat acetate 是一种有效的 PACAP 受体拮抗剂。PACAP (6-38) 作用于 PACAP I 型受体,PACAP II 型受体 VIP1 和 PACAP II 型受体 VIP2,IC50 分别为 30 nM,600 nM 和 40 nM。
TP1070 PACAP (1-27), human, ovine, rat

PACAP 1-27

PACAP (1-27) (the N-terminal fragment of PACAP-38) is a novel neuropeptides originally isolated from bovine hypothalamus, also found in humans and rats.
TP1069 PACAP (1-27), human, ovine, rat TFA

PACAP 1-27 TFA

PACAP (1-27), human, ovine, rat TFA (PACAP 1-27 TFA) is an N-terminal fragment of pacap-38 and an effective PACAP receptor antagonist. The IC50s for rat PAC1, rat VPAC1 and human VPAC2 are 3nm, 2nm and 5nm respectively.
T83510 [Arg-15,20,21,Leu17]-PACAP-Gly-Lys-Arg-NH2

BM-PACAP

[Arg-15,-20,-21,Leu17]-PACAP-Gly-Lys-Arg-NH2 (BM-PACAP) 为合成PACAP 1-27 类似物,展现出明显的松弛效应。
T36428 PACAP-related Peptide (human) (trifluoroacetate salt)

PACAP GPCR/G Protein
PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin , glucagon , glucagon-like peptide-1 , GLP-2 , and pituitary adenylate cyclase-activating polypeptide . It is expressed in normal human pancreas and adrenal gland tissue and in some tumors that produce vasoactive intestinal peptide (VIP). PRP (1-29) is secreted by CHO-K1 cells that express human recombinant preproPACAP.
TP1878 PACAP (1-38), human, ovine, rat

Pituitary Adenylate Cyclase Activating Polypeptide 38,腺苷酸环化酶激活肽-38(抗原),PACAP 1-38

PACAP GPCR/G Protein
PACAP (1-38), human, ovine, rat (Pituitary Adenylate Cyclase Activating Polypeptide 38) 是含有 38 个氨基酸残基的神经肽。它能够结合 PACAP I 型受体(IC50:4 nM)、PACAP II 型受体 VIP1(IC50:2 nM)、PACAP II 型受体 VIP2(IC50:1 nM)。
TP1722 PACAP (6-38), human, ovine, rat

PACAP (6-38), human, ovine, rat is a potent antagonist of PACAP 38. PACAP (6-38) is much more potent and selective than PACAP (6-27) in the inhibition of PACAP-27-stimulated pituitary adenylate cyclase.
T37435 PACAP-related Peptide (rat) (trifluoroacetate salt)

PACAP GPCR/G Protein
PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin , glucagon , glucagon-like peptide-1 , GLP-2 , and pituitary adenylate cyclase-activating polypeptide . It is expressed in rat hypothalamus as well as within the nerves of the median eminence, the anterior pituitary, bed nucleus of the stria terminalis, cerebellum, cerebral cortex, and amygdala. PRP is also expressed in vaginal, uterine cervica...
TP1850 PACAP-Related Peptide (PRP), human

PACAP-Related Peptide (PRP), human,a 29 amino-acid region of the PACAP precursor protein, is synthesized in quantities sufficient for biological and structural studies.
T36427 PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)

PACAP GPCR/G Protein
Pituitary adenylate cyclase-activating peptide (PACAP) (6-27) is a PACAP receptor antagonist with IC50 values of 1,500, 600, and 300 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors expressed in CHO cells. It binds to PACAP receptors on SH-SY5Y and SK-N-MC human neuroblastoma and T47D human breast cancer cells (IC50s = 24.5, 106, and 105 nM, respectively) and inhibits cAMP accumulation induced by PACAP (1-38) (Kis = 457, 102, and 283 nM, respectively, in SH-SY5Y, ...
TP1438 PACAP (6-38), human, ovine, rat TFA

PACAP (6-38), human, ovine, rat TFA is a potent PACAP receptor antagonist with IC50s of 30, 600, and 40 nM for PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2, respectively.
TP1618 PACAP-38 (31-38), human, mouse, rat

PACAP-38 (31-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production.
TP1619 PACAP-38 (16-38), human, mouse, rat

PACAP-38 (16-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production.
TP1054 PACAP (1-38), human, ovine, rat TFA

Pituitary Adenylate Cyclase Activating Polypeptide 38 (TFA)

PACAP (1-38), a novel neuropeptide isolated from the bovine hypothalamus is more active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50=7 nM). PACAP 1-38 (10-9 M) increased substance P (SP), gastrin releasing peptide (GRP),
TP1414 PACAP-38 (31-38), human, mouse, rat TFA

PACAP-38 (31-38), human, mouse, rat (TFA) demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal.
T81572 PACAP (1-38) free acid

PACAP (1-38) free acid 是一种具有多重生物功能的内源性神经肽,主要作用包括刺激胃窦运动、增进体液蛋白分泌、抑制胃泌素分泌,以及促进血管活性肠肽、胃泌素释放肽和P 物质的释放。此外,PACAP (1-38) free acid 通过与RACK1互作,可以增强N-甲基-D-天门冬氨酸受体的功能并促进脑源性神经营养因子的表达。
T80069 PACAP (6-27) (human, ovine, rat)

Pituitary adenylate cyclase-activating peptide (6-27)

PACAP (6-27) (human, ovine, rat) 是一种对PACAP受体具有拮抗作用的化合物,可以抑制犬肾上腺对外源性VIP的反应。此化合物在心血管疾病和神经系统疾病研究中展现出应用潜力。
T81571 PACAP (1-38) free acid TFA

PACAP (1-38) free acid TFA,一种内源性神经肽,能有效促进胃窦运动,增强体液蛋白分泌,同时抑制胃泌素释放。此外,它刺激血管活性肠肽、胃泌素释放肽和P物质的释放,并通过RACK1增强N-甲基-D-天门冬氨酸受体功能及脑源性神经营养因子表达。
T41005 PA-8

PACAP GPCR/G Protein
PA-8是一种小分子的的 PACAP I 型(PAC1)受体拮抗剂,有 选择性、有效性和口服活性。PA-8抑制PACAP 诱导的CREB 在PAC1-受体上的磷酸化,但对VPAC11或VPAC2受体无抑制作用。PA-8也抑制pacap 诱导的体外cAMP 水平升高(IC50 = 2 nM)和体内鞘内注射后pacap 诱导的厌恶反应和机械异位性痛。
T78105 PAC1R antagonist 1

PACAP GPCR/G Protein
PAC1R antagonist 1为一种具有口服活性的 PAC1 受体拮抗剂,可抑制由垂体腺苷酸环化酶激活多肽(PACAP)及神经损伤所诱导的异常性疼痛,可用于研究肿瘤和与免疫相关的疾病。
T76949 Zelminemab

Zelminemab (AMG-301) 是一种人单克隆抗体,可抑制 I 型 PACAP (PAC1) 受体。

化合物

PACAP (1-27), human, ovine, rat acetate
Cat.No: TP1070L
Synonym: PACAP 1-27 acetate,PACAP (1-27), human, ovine, rat acetate(127317-03-7 free base)
Target: PACAP
PACAP 1-38 acetate
Cat.No: TP1878L
Synonym:
Target: PACAP
PACAP-38 (31-38), human, mouse, rat acetate
Cat.No: TP1618L
Synonym: PACAP-38 (31-38), human, mouse, rat acetate(138764-85-9 Free base)
Target: PACAP
PACAP (6-38), human, ovine, rat acetate
Cat.No: TP1722L
Synonym:
Target: PACAP
PACAP (1-27), human, ovine, rat
Cat.No: TP1070
Synonym: PACAP 1-27
Target:
PACAP (1-27), human, ovine, rat TFA
Cat.No: TP1069
Synonym: PACAP 1-27 TFA
Target:
[Arg-15,20,21,Leu17]-PACAP-Gly-Lys-Arg-NH2
Cat.No: T83510
Synonym: BM-PACAP
Target:
PACAP-related Peptide (human) (trifluoroacetate salt)
Cat.No: T36428
Synonym:
Target: PACAP
PACAP (1-38), human, ovine, rat
Cat.No: TP1878
Synonym: Pituitary Adenylate Cyclase Activating Polypeptide 38,腺苷酸环化酶激活肽-38(抗原),PACAP 1-38
Target: PACAP
PACAP (6-38), human, ovine, rat
Cat.No: TP1722
Synonym:
Target:
PACAP-related Peptide (rat) (trifluoroacetate salt)
Cat.No: T37435
Synonym:
Target: PACAP
PACAP-Related Peptide (PRP), human
Cat.No: TP1850
Synonym:
Target:
PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)
Cat.No: T36427
Synonym:
Target: PACAP
PACAP (6-38), human, ovine, rat TFA
Cat.No: TP1438
Synonym:
Target:
PACAP-38 (31-38), human, mouse, rat
Cat.No: TP1618
Synonym:
Target:
PACAP-38 (16-38), human, mouse, rat
Cat.No: TP1619
Synonym:
Target:
PACAP (1-38), human, ovine, rat TFA
Cat.No: TP1054
Synonym: Pituitary Adenylate Cyclase Activating Polypeptide 38 (TFA)
Target:
PACAP-38 (31-38), human, mouse, rat TFA
Cat.No: TP1414
Synonym:
Target:
PACAP (1-38) free acid
Cat.No: T81572
Synonym:
Target:
PACAP (6-27) (human, ovine, rat)
Cat.No: T80069
Synonym: Pituitary adenylate cyclase-activating peptide (6-27)
Target:
PACAP (1-38) free acid TFA
Cat.No: T81571
Synonym:
Target:
PA-8
Cat.No: T41005
Synonym:
Target: PACAP
PAC1R antagonist 1
Cat.No: T78105
Synonym:
Target: PACAP
Zelminemab
Cat.No: T76949
Synonym:
Target:
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